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1561Publicado 1996“…To address these issues, we have examined the mouse immune response to La autoantigen (mLa) and the homologous human La antigen (hLa), which are components of the La(SS-B)/Ro(SS-A) ribonucleoprotein (RNP) complex targeted in systemic lupus erythematosus and primary Sjogren's syndrome. …”
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1562por Labrecque, Douglas R.“…Preliminary experiments are presented which show that SS stimulates non-proliferating adult hepatocytes to incorporate increased amounts of (3)HT dr into DNA when SS is added to the culture medium. …”
Publicado 1979
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1563por Wang, Yuan-yuan, Ma, Zhi-Yong, Li, Xiao-Dong, Wang, Jian-chun, Zhang, Wei, Li, Li, Zhang, Yun“…A low concentration of positive serum (1/100) had a small inhibitory effect on I (ss). However, positive serum at 1 : 10, 1 : 20, and 1 : 50 significantly decreased I (ss). …”
Publicado 2011
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1564por Pasieka, Tracy Jo, Collins, Lynne, O'Connor, Megan A., Chen, Yufei, Parker, Zachary M., Berwin, Brent L., Piwnica-Worms, David R., Leib, David A.“…Mice deficient for Stat1 and IFNR (Stat1(−/−) and IFNαßγR(−/−) mice) lack responsiveness to IFN and exhibit high sensitivity to various pathogens. …”
Publicado 2011
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1565“…Here we demonstrate the ability of a secreted/released T. cruzi factor to antagonize ctgf/ccn2 expression in dermal fibroblasts in response to TGF-ß, lysophosphatidic acid or serum, where agonist-induced phosphorylation of the mitogen-activated protein (MAP) kinases Erk1/2, p38 and JNK was also inhibited. …”
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1566“…A novel positive-sense, single-stranded RNA (+ssRNA) virus (Halastavi árva RNA virus, HalV; JN000306) with di-cistronic genome organization was serendipitously identified in intestinal contents of freshwater carps (Cyprinus carpio) fished by line-fishing from fishpond “Lőrinte halastó” located in Veszprém County, Hungary. …”
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1567“…In the present investigation, a Penicillum sp. SS1 isolated from degrading woody material was found to produce moderately thermoactive and alkalistable endo-β-1,4-xylanase (xylanase). …”
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1568por Koga, Hironori, Tsedensodnom, Orkhontuya, Tomimaru, Yoshito, Walker, Evan J., Lee, Han Chu, Kim, Kang Mo, Yano, Hirohisa, Wands, Jack R., Kim, Miran“…Here, we show the oncogenic potential of human TCF-4 isoforms based on the expression of a single conserved SxxSS motif. METHODS: We investigated the TCF-4J and K isoform pair characterized by the presence (K) or absence (J) of the SxxSS motif. …”
Publicado 2012
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1569“…Commercial pure titanium (Ti), titanium alloy (Ti6Al4V), and stainless steel 316L (SS) in particulate form with <20 μm in size were used. …”
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1570por Forget, Marie-Andrée, Huon, Yannick, Reuben, Alexandre, Grange, Cécile, Liberman, Moïshe, Martin, Jocelyne, Mes-Masson, Anne-Marie, Arbour, Nathalie, Lapointe, Réjean“…It is possible to differentiate mouse CD8(+) T cells towards stem cell-like memory (T(SCM)) phenotype upon TCR stimulation with Wnt/ß-catenin pathway activation. Here, we evaluated if T(SCM) can be obtained from human mature CD8(+) T cells following TCR and Wnt/ß-catenin activation through treatment with the chemical agent 4,6-disubstituted pyrrolopyrimidine (TWS119), which inhibits the glycogen synthase kinase-3β (GSK-3β), key inhibitor of the Wnt pathway. …”
Publicado 2012
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1571“…The alternative sigma factor RpoN is an essential colonization factor of Vibrio cholerae and controls important cellular functions including motility and type VI secretion (T6SS). The RpoN regulon has yet to be clearly defined in T6SS-active V. cholerae isolates, which use T6SS to target both bacterial competitors and eukaryotic cells. …”
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1572“…T4SS was once believed to be present only in Gram-negative bacteria. …”
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1573“…Based on the capsular type, 33 serotypes of S. suis have been described, with serotype 2 (SS2) being the most frequently isolated from diseased piglets. …”
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1574“…Redox-coupled folding pathways of bovine pancreatic ribonuclease A (RNase A) with four intramolecular disulfide (SS) bonds comprise three phases: (I) SS formation to generate partially oxidized intermediate ensembles with no rigid folded structure; (II) SS rearrangement from the three SS intermediate ensemble (3S) to the des intermediates having three native SS linkages; (III) final oxidation of the last native SS linkage to generate native RNase A. …”
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1575por de Souza, Dziedzom K., Koudou, Benjamin G., Bolay, Fatorma K., Boakye, Daniel A., Bockarie, Moses J.Enlace del recurso
Publicado 2014
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1576por Lind, Andreas, Brekke, Kristin, Pettersen, Frank Olav, Mollnes, Tom Eirik, Trøseid, Marius, Kvale, DagEnlace del recurso
Publicado 2014
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1577“…Kisspeptins are products of KiSS-1 gene. Leptin and adiponectin are modulators of KiSS-1 expression in the hypothalamus. …”
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1579“…Pharmacological inhibition of NADPH oxidase, PKC-a, PKC-ß or PKC-ß(I) via their specific inhibitors and neutralisation of O(2)(•-) by a cell-permeable superoxide dismutase mimetic, MnTBAP normalised all the aforementioned increases induced by hyperglycaemia. …”
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1580“…To foster the translation of these models to clinical practice, they have been incorporated into a web-based application, the Cardiac Health Risk Stratification System (CHRiSS). As clinical experience with LVAD therapy continues to grow, and additional data is collected, we aim to continually update these BN models to improve their accuracy and maintain their relevance. …”
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