Crystallographic analysis of human hemoglobin elucidates the structural basis of the potent and dual antisickling activity of pyridyl derivatives of vanillin. Corrigendum

por Abdulmalik, Osheiza, Ghatge, Mohini S., Musayev, Faik N., Parikh, Apurvasena, Chen, Qiukan, Yang, Jisheng, Nnamani, Ijeoma, Danso-Danquah, Richmond, Eseonu, Dorothy N., Asakura, Toshio, Abraham, Donald J., Venitz, Jurgen, Safo, Martin K.
Publicado 2011

VZHE-039, a novel antisickling agent that prevents erythrocyte sickling under both hypoxic and anoxic conditions

por Abdulmalik, Osheiza, Pagare, Piyusha P., Huang, Boshi, Xu, Guoyan G., Ghatge, Mohini S., Xu, Xiaomeng, Chen, Qiukan, Anabaraonye, Nancy, Musayev, Faik N., Omar, Abdelsattar M., Venitz, Jürgen, Zhang, Yan, Safo, Martin K.
Publicado 2020

Proteomic pathways associated with developing severe disease for patients with COVID-19: A biologic analysis of data from two multicenter randomized controlled trials encompassing...

por Samorodnitsky, Sarah, Castro-Pearson, Sandra, Yang, Kaifeng, Lotfi-Emran, Sahar, Ingraham, Nicholas E., Bramante, Carolyn, Geising, Sarah, Jones, Emma K., Wacker, David, Puskarich, Michael, Lusczek, Elizabeth, Safo, Sandra, Tignanelli, Christopher J.
Publicado 2023

Identification of a Small Molecule that Increases Hemoglobin Oxygen Affinity and Reduces SS Erythrocyte Sickling

por Nakagawa, Akito, Lui, Francine E., Wassaf, Dina, Yefidoff-Freedman, Revital, Casalena, Dominick, Palmer, Michelle A., Meadows, Jacqueline, Mozzarelli, Andrea, Ronda, Luca, Abdulmalik, Osheiza, Bloch, Kenneth D., Safo, Martin K., Zapol, Warren M.
Publicado 2014

Antimicrobial and in silico studies of the triterpenoids of Dichapetalum albidum

por Chama, Mary A., Dziwornu, Godwin A., Popli, Elizabeth, Mas-Claret, Eduard, Egyir, Beverly, Ayine-Tora, Daniel M., Owusu, Kofi B-A., Reid, David G., Osei-Safo, Dorcas, Duer, Melinda, Mulholland, Dulcie, Bender, Andreas
Publicado 2023

Improving the Solubility and Oral Bioavailability of a Novel Aromatic Aldehyde Antisickling Agent (PP10) for the Treatment of Sickle Cell Disease

por Ahmed, Tarek A., El-Say, Khalid M., Abd-Allah, Fathy I., Omar, Abdelsattar M., El-Araby, Moustafa E., Muhammad, Yosra A., Pagare, Piyusha P., Zhang, Yan, Mohmmad, Khadijah A., Abdulmalik, Osheiza, Safo, Martin K.
Publicado 2021

Mechanistic Analysis of the VirA Sensor Kinase in Agrobacterium tumefaciens Using Structural Models

por Swackhammer, Addison, Provencher, Edward A. P., Donkor, Akua K., Garofalo, Jessica, Dowling, Sinead, Garchitorena, Kathleen, Phyo, Ahkar, Ramírez Veliz, Nicky, Karen, Matthew, Kwon, Annie, Diep, Rich, Norris, Michael, Safo, Martin K., Pierce, B. Daniel
Publicado 2022

Antischistosomal, antionchocercal and antitrypanosomal potentials of some Ghanaian traditional medicines and their constituents

por Twumasi, Emmanuella Bema, Akazue, Pearl Ihuoma, Kyeremeh, Kwaku, Gwira, Theresa Manful, Keiser, Jennifer, Cho-Ngwa, Fidelis, Flint, Adrian, Anibea, Barbara, Bonsu, Emmanuel Yeboah, Amewu, Richard K., Amoah, Linda Eva, Appiah-Opong, Regina, Osei-Safo, Dorcas
Publicado 2020

Correction: Antischistosomal, antionchocercal and antitrypanosomal potentials of some Ghanaian traditional medicines and their constituents

por Twumasi, Emmanuella Bema, Akazue, Pearl Ihuoma, Kyeremeh, Kwaku, Gwira, Theresa Manful, Keiser, Jennifer, Cho-Ngwa, Fidelis, Flint, Adrian, Anibea, Barbara, Bonsu, Emmanuel Yeboah, Amewu, Richard K., Amoah, Linda Eva, Appiah-Opong, Regina, Osei-Safo, Dorcas
Publicado 2023

Glycine/NMDA Receptor Pathway Mediates the Rapid-onset Antidepressant Effect of Alkaloids From Trichilia Monadelpha

por Kukuia, Kennedy Kwami Edem, Mensah, Jeffrey Amoako, Amoateng, Patrick, Osei-Safo, Dorcas, Koomson, Awo Efua, Torbi, Joseph, Adongo, Donatus Wewura, Ameyaw, Elvis Ofori, Ben, Inemesit Okon, Amponsah, Seth Kwabena, Bugyei, Kwasi Agyei, Asiedu-Gyekye, Isaac Julius
Publicado 2021

Design, Synthesis, and Investigation of Novel Nitric Oxide (NO)-Releasing Aromatic Aldehydes as Drug Candidates for the Treatment of Sickle Cell Disease

por Huang, Boshi, Ghatge, Mohini S., Donkor, Akua K., Musayev, Faik N., Deshpande, Tanvi M., Al-Awadh, Mohammed, Alhashimi, Rana T., Zhu, Hongmei, Omar, Abdelsattar M., Telen, Marilyn J., Zhang, Yan, McMahon, Tim J., Abdulmalik, Osheiza, Safo, Martin K.
Publicado 2022

Characterization of the Escherichia coli pyridoxal 5′‐phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability

por Tramonti, Angela, Ghatge, Mohini S., Babor, Jill T., Musayev, Faik N., di Salvo, Martino Luigi, Barile, Anna, Colotti, Gianni, Giorgi, Alessandra, Paredes, Steven D., Donkor, Akua K., Al Mughram, Mohammed H., de Crécy‐Lagard, Valérie, Safo, Martin K., Contestabile, Roberto
Publicado 2022

“Who needs an app? Fertility patients’ use of a novel mobile health app”

por Miner, Skye A, Gelgoot, Eden N, Lahuec, Alix, Wunderlich, Samantha, Safo, Darryl, Brochu, Felicia, Dawadi, Shrinkhala, Robins, Stephanie, Bernadette, Siobhan, O’Connell, Laura, Chan, Peter, Ells, Carolyn, Holzer, Hananel, Lo, Kirk, Mahutte, Neal, Ouhilal, Sophia, Rosberger, Zeev, Tulandi, Togas, Zelkowitz, Phyllis
Publicado 2022

Drug discovery research in Ghana, challenges, current efforts, and the way forward

por Amewu, Richard Kwamla, Amoateng, Patrick, Arthur, Patrick Kobina, Asare, Prince, Asiamah, Isaac, Boamah, Daniel, Darko Otchere, Isaac, Dzidzor Amengor, Cedric, Ekuadzi, Edmund, Chibale, Kelly, Farrell, Susan Jane, Appiah-Oppong, Regina, Osei-Safo, Dorcas, David Read, Kevin, Hugh Gilbert, Ian, Yeboah-Manu, Dorothy
Publicado 2022

Development of a proteomic signature associated with severe disease for patients with COVID-19 using data from 5 multicenter, randomized, controlled, and prospective studies

por Castro-Pearson, Sandra, Samorodnitsky, Sarah, Yang, Kaifeng, Lotfi-Emran, Sahar, Ingraham, Nicholas E., Bramante, Carolyn, Jones, Emma K., Greising, Sarah, Yu, Meng, Steffen, Brian, Svensson, Julia, Åhlberg, Eric, Österberg, Björn, Wacker, David, Guan, Weihua, Puskarich, Michael, Smed-Sörensen, Anna, Lusczek, Elizabeth, Safo, Sandra E., Tignanelli, Christopher J.
Publicado 2023

Rapid and reproducible characterization of sickling during automated deoxygenation in sickle cell disease patients

por Rab, Minke A.E., van Oirschot, Brigitte A., Bos, Jennifer, Merkx, Tesy H., van Wesel, Annet C.W., Abdulmalik, Osheiza, Safo, Martin K., Versluijs, Birgitta A., Houwing, Maite E., Cnossen, Marjon H., Riedl, Jurgen, Schutgens, Roger E.G., Pasterkamp, Gerard, Bartels, Marije, van Beers, Eduard J., van Wijk, Richard
Publicado 2019

Sphingosine-1-phosphate promotes erythrocyte glycolysis and oxygen release for adaptation to high-altitude hypoxia

por Sun, Kaiqi, Zhang, Yujin, D'Alessandro, Angelo, Nemkov, Travis, Song, Anren, Wu, Hongyu, Liu, Hong, Adebiyi, Morayo, Huang, Aji, Wen, Yuan E., Bogdanov, Mikhail V., Vila, Alejandro, O'Brien, John, Kellems, Rodney E., Dowhan, William, Subudhi, Andrew W., Jameson-Van Houten, Sonja, Julian, Colleen G., Lovering, Andrew T., Safo, Martin, Hansen, Kirk C., Roach, Robert C., Xia, Yang
Publicado 2016