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621por Hoke, Stephen M. T., Irina Mutiu, A., Genereaux, Julie, Kvas, Stephanie, Buck, Michael, Yu, Michael, Gloor, Gregory B., Brandl, Christopher J.“…Tra1 is a component of the Saccharomyces cerevisiae SAGA and NuA4 complexes and a member of the PIKK family, which contain a C-terminal phosphatidylinositol 3-kinase-like (PI3K) domain followed by a 35-residue FATC domain. …”
Publicado 2010
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622por Kalfopoulou, Ermioni, Laverde, Diana, Miklic, Karmela, Romero-Saavedra, Felipe, Malic, Suzana, Carboni, Filippo, Adamo, Roberto, Lenac Rovis, Tihana, Jonjic, Stipan, Huebner, Johannes“…From this process, two highly specific IgG1(κ) MAbs were obtained, one against the polysaccharide (DHG.01) and one against the protein (SagA.01). Both MAbs exhibited good opsonic killing against the target bacterial strains: DHG.01 showed 90% killing against E. faecalis type 2, and SagA.01 showed 40% killing against E. faecium 11231/6. …”
Publicado 2019
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623por Itakura, Alan K., Chan, Kher Xing, Atkinson, Nicky, Pallesen, Leif, Wang, Lianyong, Reeves, Gregory, Patena, Weronika, Caspari, Oliver, Roth, Robyn, Goodenough, Ursula, McCormick, Alistair J., Griffiths, Howard, Jonikas, Martin C.“…We find that the mutant’s phenotypes are due to disruption of a gene, which we call StArch Granules Abnormal 1 (SAGA1) because starch sheath granules, or plates, in mutants lacking SAGA1 are more elongated and thinner than those of wild type. …”
Publicado 2019
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624por Badmos, Hammed, Cobbe, Neville, Campbell, Amy, Jackson, Richard, Bennett, Daimark“…Nonstop is a component of the Spt-Ada-Gcn5-acetyltransferase (SAGA) transcriptional coactivator complex, but SAGA’s histone acetyltransferase module, which does not bind to expanded or merlin, is dispensable for migration. …”
Publicado 2021
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625“…Suppression of TBP dynamics via removal of the Mot1 ATPase partially restores normal transcriptional activity to Med16-depleted cells, suggesting that cMed/tail separation results in an imbalance in the levels of PIC formation at SAGA-requiring and TFIID-dependent genes. We propose that the preferential regulation of SAGA-requiring genes by tailed Mediator helps maintain a proper balance of transcription between these genes and those more dependent on TFIID.…”
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626por Oda, Yasutomo, Onishi, Hirotaka, Sakemi, Takanobu, Fujimoto, Kazuma, Koizumi, Shunzo“…Fifteen years of undergraduate medical education curriculum reform at Saga Medical School was evaluated by measuring medical students’ communication and interpersonal skills with a patient satisfaction questionnaire developed by the American Board of Internal Medicine. …”
Publicado 2014
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627Distinct patterns of histone acetyltransferase and Mediator deployment at yeast protein-coding genespor Bruzzone, Maria Jessica, Grünberg, Sebastian, Kubik, Slawomir, Zentner, Gabriel E., Shore, David“…The transcriptional coactivators Mediator and two histone acetyltransferase (HAT) complexes, NuA4 and SAGA, play global roles in transcriptional activation. …”
Publicado 2018
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628“…The epigenetic modulatory SAGA complex is involved in various developmental and stress responsive pathways in plants. …”
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629“…METHODS: We evaluated the feasibility and effectiveness of SAGA in a hybrid phase 1/2, randomized controlled trial. …”
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631“…Coactivator recruitment was highly interdependent such that mutations disrupting SAGA impaired recruitment of SWI/SNF and vice versa. …”
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632“…Here, we show that Gad8 physically interacts with proteins that regulate transcription, including subunits of the Spt-Ada-Gcn5-acetyltransferase (SAGA) complex and the BET bromodomain protein Bdf2. …”
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633“…Here, we report that the SAGA DUB module and TREX-2 distinctly regulate yeast replicative lifespan in a Sir2-dependent and -independent manner, respectively. …”
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634por Essaadia, Adaze, Abdellah, Algouti, Ahmed, Algouti, Abdelouahed, Farah, Kamal, Elbadaoui“…In addition, the presented results underline that open-source software, such as SAGA GIS and SNAP can provide satisfactory results for vegetation coverage dynamics.…”
Publicado 2022
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635por Güler, Olcay, Mahirogulları, Mahir, Mutlu, Serhat, Çerci, Mehmet Halis, Şeker, Ali, Çakmak, Selami“…Statistically significant difference was detected between SAGA and FAGA values of operated knees in both groups (p<0.05). …”
Publicado 2014
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636por Bastone, Antonella L., Dziadek, Violetta, John-Neek, Philipp, Mansel, Friederike, Fleischauer, Jenni, Agyeman-Duah, Eric, Schaudien, Dirk, Dittrich-Breiholz, Oliver, Schwarzer, Adrian, Schambach, Axel, Rothe, Michael“…We previously developed the In Vitro Immortalization Assay (IVIM) and Surrogate Assay for Genotoxicity Assessment (SAGA) for pre-clinical genotoxicity prediction of integrating vectors. …”
Publicado 2023
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637por Bharati, Akhilendra Pratap, Kashif, Mohd, Chaturvedi, Sumit Kumar, Khan, Rizwan Hasan, Ahmad, Abrar“…Sus1 is a transcription export factor and part of both the SAGA and the TREX-2 complex. The competitive exchange of Sus1 molecule between SAGA and TREX-2 complex modulates their function which is credited to structural plasticity of Sus1. …”
Publicado 2020
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