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701“…The extent of nucleosome shifting is closely related to the dynamic range of gene transcription and generally related to DNA sequence properties and use of the coactivators TFIID or SAGA. However, dynamic gene expression is not limited to SAGA-regulated promoters and is an inherent feature of most genes. …”
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702por Zhang, Jing, Luo, Nan, Tian, Yu, Li, Jiazhi, Yang, Xiaozhou, Yin, Huimin, Xiao, Congshu, Sheng, Jie, Li, Yang, Tang, Bo, Li, Rongkuan“…USP22, a member of the deubiquitinases (DUBs) family, is known to be a key subunit of the human Spt-Ada-Gcn5 acetyltransferase (hSAGA) transcriptional cofactor complex. Within hSAGA, USP22 removes ubiquitin from histone proteins, thus regulating the transcription and expression of downstream genes. …”
Publicado 2017
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703por Kawachi, Kojiro, Sakata, Yasuhisa, Hara, Megumi, Takeshita, Eri, Kawakubo, Hiroharu, Yamaguchi, Daisuke, Okamoto, Norihiro, Shimoda, Ryo, Iwakiri, Ryuichi, Tsuruoka, Nanae, Kusano, Motoyasu, Fujimoto, Kazuma“…Among them, 3505 subjects (M/F: 1922/1583) were underwent a routine medical checkup at one of five hospitals in Saga, Japan from January 2013 to December 2013. The others were 581 (M/F: 322/259) healthy young volunteers at the Saga Medical School from April 2007 to March 2013. …”
Publicado 2017
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704por van Welsem, Tibor, Korthout, Tessy, Ekkebus, Reggy, Morais, Dominique, Molenaar, Thom M, van Harten, Kirsten, Poramba-Liyanage, Deepani W, Sun, Su Ming, Lenstra, Tineke L, Srivas, Rohith, Ideker, Trey, Holstege, Frank C P, van Attikum, Haico, El Oualid, Farid, Ovaa, Huib, Stulemeijer, Iris J E, Vlaming, Hanneke, van Leeuwen, Fred“…Increased Dot1 dosage was found to promote H2Bub1 in a dose-dependent manner and this was exacerbated by the loss of SAGA-DUB activity, which also caused a negative genetic interaction. …”
Publicado 2018
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705por Zhu, Hongling, Liu, Lianyong, Ren, Li, Ma, Junhua, Hu, Shuanggang, Zhu, Zhaohui, Zhao, Xuemei, Shi, Chao, Wang, Xing, Zhang, Chaobao, Gu, Mingjun, Li, Xiangqi“…In the GO category cellular component, the co-expressed genes were accumulated in ‘Spt-Ada-Gcn5 acetyltransferase (SAGA)-type complex’ and ‘SAGA complex’, and in the category molecular function, they were concentrated in ‘hexosaminidase activity’, ‘cytoskeletal adaptor activity’, ‘cyclin binding’ and ‘β-N-acetylhexosaminidase activity’. …”
Publicado 2020
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706por Kimura, Sakiko, Emoto, Akiko, Yoshimura, Mariko, Arimizu, Kota, Kamura, Tomoko, Sogawa, Rintaro, Mizuta, Kikumi, Tagomori, Yasuhiro, Natsuaki, Masahiro, Kajiwara, Masataka, Tsuruoka, Nanae, Yakushiji, Yusuke, Tanigawa, Yoshinori, Takamatsu, Chihiro, Danjo, Atsushi, Kamohara, Keiji, Hirakawa, Naomi, Sakaguchi, Yoshiro, Noguchi, Mitsuru, Noshiro, Hirokazu, Kawaguchi, Atsushi, Sueoka, Eisaburo, Narisawa, Yutaka, Kimura, Shinya“…We have therefore developed an online application for perioperative drug discontinuation and resumption management, named Saga Application for Management of Drug Holidays in PeriOperative Periods (SAMPOP). …”
Publicado 2020
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707“…The mitochondrial genome of M. costalis from Saga Prefecture was identified as a circular molecule of 15,488 bp, similar to that found in other M. costalis populations. …”
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708por Dülfer, Jasmin, Yan, Hao, Brodmerkel, Maxim N., Creutznacher, Robert, Mallagaray, Alvaro, Peters, Thomas, Caleman, Carl, Marklund, Erik G., Uetrecht, Charlotte“…While the almost identical strains GII.4 Saga and GII.4 MI001 share glycan-induced dynamics, the dynamics differ in the emerging GII.17 Kawasaki 308 and rare GII.10 Vietnam 026 strain. …”
Publicado 2021
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709“…This study extends the evidence for a link between pleomorphism and virulence in Cryptococcus, with a likely role for epigenetic mechanisms mediated by SAGA-induced histone acetylation.…”
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710por Daneshpajouh, Habib, Chen, Bowen, Shokraneh, Neda, Masoumi, Shohre, Wiese, Kay C, Libbrecht, Maxwell W“…MOTIVATION: Segmentation and genome annotation (SAGA) algorithms are widely used to understand genome activity and gene regulation. …”
Publicado 2022
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711
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712
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713“…Here, we use several MSA tools such as ClustalX, Align-m, T-Coffee, SAGA, ProbCons, MAFFT, MUSCLE and DIALIGN to illustrate comparative phylogenetic trees analysis for two datasets. …”
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714por Bowers, J. Z.“…This is a description, based largely on personal discussions, of the contributions of men from the Yale University School of Medicine to the saga of the immediate and long-term studies on the medical effects of the atomic bombs at Hiroshima and Nagasaki. …”
Publicado 1983
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715“…To effectively develop systems medicine, we should take advantage of the lessons of the HLA saga, emphasizing the importance of exploring a fascinating but mysterious biology, now using systems principles, pioneering new technology developments and creating shared biological and information resources.…”
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716por Van Overwalle, Geertrui“…– Patents for genes and genetic tests – Patent thickets and refusal to license – Facilitating access to patents – Research exemption, licensing, patent pools, clearing houses – Compulsory licenses – BRCA saga…”
Publicado 2010
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717por Niewiadomska-Cimicka, Anna, Hache, Antoine, Le Gras, Stéphanie, Keime, Céline, Ye, Tao, Eisenmann, Aurelie, Harichane, Imen, Roux, Michel J., Messaddeq, Nadia, Clérin, Emmanuelle, Léveillard, Thierry, Trottier, Yvon“…SCA7 is caused by a polyglutamine expansion in the ATXN7 protein, a subunit of the transcriptional coactivator SAGA that acetylates histone H3 to deposit narrow H3K9ac mark at DNA regulatory elements of active genes. …”
Publicado 2022
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718por Sahu, S K, Ebara, S, Nozaki, T, Behari, S, Fujimoto, H, Kobayashi, S, Murakami, A, Yang, M, Matsumoto, S, Abe, K, Fujii, Y, Kurihara, Y, Lee, M H, Liu, F, Mäki, A, Omori, T, Sagawa, H, Sakai, Y, Sasaki, T, Sugimoto, Y, Takaiwa, Y, Terada, S, Kirk, P, Wang, T J, Abashian, Alexander, Gotow, K, Mattson, M E, Piilonen, L E, Sterner, K L, Choi, S K, Rosenfeld, C, Zheng, L Y, Breedon, R E, Winston, K, Lander, R L, Rowe, J, Smith, J R, Stuart, D, Kanda, S, Olsen, S L, Ueno, K, Tanaka, R, Kajino, F, Aso, T, Miyano, K, Miyata, H, Nakajima, N, Ohkubo, K, Oyoshi, M, Sato, M, Shirai, M, Takashimizu, N, Yamashita, Y, Schnetzer, S R, Vinson, J F, Bodek, Arie, Kim, B J, Velissaris, C, Kang, J S, Kim, D Y, Lee, K B, Kim, S K, Myung, S S, Son, DEnlace del recurso
Publicado 1995
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719por Weill, Kurt, 1900-1950Tabla de Contenidos: “…One life to live (3:09) ; A saga of Jenny (4:55) ; My ship (2:59) / Weill ; Hart ; Gershwin.…”
Publicado 1993
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720por Lynch, Rebekka, Flores-Torres, Mario H., Hinojosa, Gabriela, Aspelund, Thor, Hauksdóttir, Arna, Kirschbaum, Clemens, Catzin-Kuhlmann, Andres, Lajous, Martín, Valdimarsdottir, Unnur“…We collected hair samples from 881 women from the Mexican Teachers’ Cohort (MTC) and 398 women from the Icelandic SAGA pilot-cohort following identical protocols. …”
Publicado 2022
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