“…Gcn5, the acetyltransferase within the SAGA complex, was found to regulate histone methylation and H2B ubiquitination. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We identified a large number of Mediator-interacting proteins and protein complexes, such as RNA polymerase II, general transcription factors, a large number of transcriptional activators, the SAGA complex, chromatin remodeling complexes, histone chaperones, highly acetylated histones, as well as proteins playing a role in co-transcriptional processes, such as splicing, mRNA decapping and mRNA decay. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We provide genetic and cellular evidence that AP-2 interacts with endocytic markers SlaB(End4) and SagA(End3) and the lipid flippases DnfA and DnfB in the sub-apical collar region of hyphae. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…METHODS: Between November 2015 and February 2016, we conducted chart reviews of 315 patients hospitalized between April 2014 and March 2015 in four middle-sized acute-care hospitals in Shizuoka, Kochi, Fukuoka, and Saga Prefectures and used them as reference standards. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The segregation defect of a ts histone H2B mutant is rescued if it fails to be deubiquitinated by the SAGA complex, because H2B is stabilized by monoubiquitination.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The absence of a body and any associated post burial decay fauna implies its exhumation and disposal elsewhere and this is discussed in the context of other exhumed medieval burials and Saga and other sources.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…EPA Storm Water Management Model (SWMM), QGis, PostgreSQL, PostGIS, SagaGIS, and GrassGIS. Each of these tools alone cannot provide all the necessary functionalities for large-scale projects, but once linked to GISWATER, a unique, fast, efficient, and accurate work methodology results. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This paper proposes a partitioning technique SAGA (Skew-Aware Grid pArtitioning) based on the hotspots, which is more appropriate to adjust the domain size of the dataset. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In yeast, H2B-Ub is deubiquitinated by Ubp8, a subunit of SAGA, and Ubp10. Although they target the same substrate, loss of Ubp8 and Ubp10 cause different phenotypes and alter the transcription of different genes. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In this study, we analyzed the complete mitochondrial genome of the Mnais pruinosa Selys, 1853 from Saga Prefecture, Japan. The mitochondrial genome of M. pruinosa was identified as a circular molecule of 15,494 bp, and was found to be similar to that of other damselfly species. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…[Participants and Methods] In total, 235 questionnaires were distributed to parents at special support schools, pediatric hospitals, home-visit nursing stations, and after-school daycare services in Tokyo, Gunma, Hiroshima, and Saga prefectures in Japan. Data related to the Participation and Environment Measure for Children and Youth, age, height, weight, gross motor function, presence of medical care, diagnosis, and parental age were recorded for school-aged children. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Furthermore, we find that the repressor Rpd3 remains associated with Ume6 after the transactivator Ime1 has joined the complex and that the Gcn5 and Tra1 components of the SAGA complex bind to the promoter of IME2 in an Ime1-dependent fashion to induce transcription of the early meiosis-specific genes. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Understanding the history of RTX in SLE would be instructive in the hydroxychloroquine (HCQ) saga in COVID-19. Three steps would be necessary and sufficient before definitively closing the debate: 1) determine the effective and safe dose of HCQ, as well as the minimum duration of treatment in COVID-19; 2) define the profile of patients in whom HCQ would be more likely to be effective (especially in asymptomatic patients and/or at the onset of the first signs of the disease) and 3) conduct one or more multicentre RCT to evaluate the efficacy and safety of HCQ in COVID-19 in SSA.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here we report that upon deletion of ADA2, encoding a component of the ADA and SAGA transcriptional adaptor/histone acetyltransferase complexes, the efficiency of AMT significantly increased regardless of whether integration of T‐DNA was mediated by homologous or non‐homologous recombination. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The personal experience of the author's teachings in rehabilitation medicine at Saga University medical school is described. Emphasis is placed on experiential learning on subjects that are current and state-of-the-art in Japan including robotics. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…As Jayawardhana recounts a captivating saga of scientific discovery and celebrates a glorious human quest, he reveals why the next decade of neutrino hunting will redefine how we think about physics, cosmology, and our lives on Earth.…”
Enlace del recurso

“…In this study, a viral metagenomic approach was employed to investigate the fecal virome of black-necked cranes in Saga County, Shigatse City, Tibet, China. The identified virus families carried by black-necked cranes mainly include Genomoviridae, Parvoviridae, and Picornaviridae. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…RESULTS: Two-dimensional representations of the 19S and 20S proteasome, mediator, and SAGA complexes were generated and overlaid with high quality pairwise interaction data, core-module-attachment classifications from affinity purifications of complexes and predicted domain-domain interactions. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…FINDINGS: A cross-sectional, self-administered anonymous questionnaire was distributed to 60 resident staffs at Saga University Hospital in Japan. Forty residents completed and returned the questionnaire. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In the nucleus we observed that the subunits of the Ino80, RSC, and SAGA complexes function in the similar epistatic group that shares significant overlap with the homologous recombination genes. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso