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821“…Mutations that cause lethality in combination with spt10Δ include particular components of the SAGA complex as well as asf1Δ and hir1Δ. Partial suppressors of the spt10Δ growth defect include mutations that perturb cell-cycle progression through the G1/S transition, S phase, and G2/M. …”
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822“…We found that deletion of ubp8, encoding the Spt-Ada-Gcn5-Acetyl transferase (SAGA) complex associated DUB, suppressed temperature-sensitive phenotypes of APC/C mutants cut9-665, lid1-6, cut4-533, and slp1-362. …”
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823por Nguyen, Thi Thuy Trang, Lim, Julia Sze Lynn, Tang, Richard Ming Yi, Zhang, Louxin, Chen, Ee Sin“…Our findings show that the chromatin-regulating RSC and SAGA complexes act with Top2 in a cluster that is functionally distinct from the Ino80 complex. …”
Publicado 2015
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824por Mason, Amanda G., Garza, Renee M., McCormick, Mark A., Patel, Bhumil, Kennedy, Brian K., Pillus, Lorraine, La Spada, Albert R.“…Sgf73, a core component of SAGA, is the yeast orthologue of ataxin‐7, which undergoes CAG–polyglutamine repeat expansion leading to the human neurodegenerative disease spinocerebellar ataxia type 7 (SCA7). …”
Publicado 2017
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825por Shibuki, Taro, Otsuka, Taiga, Isoda, Hiroshi, Araki, Norimasa, Kubotsuv, Yoshihito, Kawaguchi, Yasunori, Nakashita, Shunya, Yoshioka, Wataru, Kawazoe, Seiji, Kawasoe, Hiroaki, Ide, Yasushi, Mizuta, Toshihiko“…MATERIAL/METHODS: We reviewed the records of 53 patients diagnosed with type 1 AIH based on the revised scoring system proposed by the International Autoimmune Hepatitis Group (IAIHG) between 2009 and 2014 at 4 hospitals belonging to the Saga Study Group of Liver Diseases (SASLD). We analyzed the differences in background characteristics between patients with or without relapse. …”
Publicado 2017
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826por Nonaka, Sayuri, Fujii, Susumu, Hara, Megumi, Morita, Shigeki, Sueoka, Eisaburo, Node, Koichi, Fujimoto, Kazuma“…The Diagnosis Procedure Combination data were gathered from 2010 through to 2015 with 63,390 cases at Saga University Hospital. The occurrence of concern factors of aspiration pneumonia during hospitalization were compared in the two time periods set (2010–2012 and 2013–2015). …”
Publicado 2018
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827por Gong, Zhen, Liu, Jianyun, Xie, Xin, Xu, Xiaoyuan, Wu, Ping, Li, Huimin, Wang, Yaqin, Li, Weidong, Xiong, Jianjun“…In the nucleus, USP22 functions as one subunit of the SAGA to regulate gene transcription. However, the genome-wide USP22 binding sites and its direct target genes are yet clear. …”
Publicado 2018
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828por Chen, Yun, Wang, Jing, Yang, Nan, Wen, Ziyue, Sun, Xuepeng, Chai, Yunrong, Ma, Zhonghua“…We show that a compound secreted by the bacteria (phenazine-1-carboxamide) directly affects the activity of fungal protein FgGcn5, a histone acetyltransferase of the SAGA complex. This leads to deregulation of histone acetylation at H2BK11, H3K14, H3K18, and H3K27 in F. graminearum, as well as suppression of fungal growth, virulence, and mycotoxin biosynthesis. …”
Publicado 2018
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829por Esvelt, Kevin M.“…Whether or not the benefits justified the risks, the horsepox saga provides ample reason to upgrade the current system for screening synthesized DNA for hazardous sequences, which does not cover the majority of firms and cannot reliably prevent the assembly of potentially pandemic pathogens. …”
Publicado 2018
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830por Elsayed, Ayman Khamis, Skuhravá, Marcela, Ohta, Kazuki, Yoshida, Satoshi, Tokuda, Makoto“…In 2018, an undescribed Massalongia species was discovered forming leaf galls on the midveins of B. grossa on Mount Tara, Saga Prefecture, Kyushu, Japan. In this study the species is described as M. nakamuratetsui Elsayed & Tokuda, sp. nov., and a DNA barcode provided for it. …”
Publicado 2020
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831por Caydasi, Ayse Koca, Khmelinskii, Anton, Darieva, Zoulfia, Kurtulmus, Bahtiyar, Knop, Michael, Pereira, Gislene“…This mitotic slippage required the Cdc14-early anaphase release pathway and other factors including the SAGA (Spt-Ada-Gcn5 acetyltransferase) histone acetyltransferase complex, proteasome components and the mitotic cyclin-dependent kinase inhibitor Sic1. …”
Publicado 2023
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832por Chau, Sabrina, Gao, Jie, Diao, Annette J., Cao, Shi Bo, Azhieh, Amirahmad, Davidson, Alan R., Meneghini, Marc D.“…Using a complementary loss of function approach, we identify new antiviral functions for the conserved RNA exonucleases REX2 and MYG1; the SAGA and PAF1 chromatin regulatory complexes; and HSF1, the master transcriptional regulator of the proteostatic stress response. …”
Publicado 2023
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833por Yague-Sanz, Carlo, Migeot, Valérie, Larochelle, Marc, Bachand, François, Wéry, Maxime, Morillon, Antonin, Hermand, Damien“…The Pcr1 transcription factor participates in the recruitment of Pol II, which affects local histone occupancy through the associated SAGA complex and a Pol II phospho-S2 CTD / Mst2 pathway. …”
Publicado 2023
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834“…Among the histone acetyltransferases, ELP3 and KAT5 and members of the ATAC, NSL, and SAGA acetyltransferase complexes are affected in uninvolved skin. …”
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835por Gaillard, Hélène, Tous, Cristina, Botet, Javier, González-Aguilera, Cristina, Quintero, Maria José, Viladevall, Laia, García-Rubio, María L., Rodríguez-Gil, Alfonso, Marín, Antonio, Ariño, Joaquín, Revuelta, José Luis, Chávez, Sebastián, Aguilera, Andrés“…Our data provide evidence that subunits of the SAGA and Ccr4-Not complexes, Mediator, Bre1, Bur2, and Fun12 affect transcription elongation to different extents. …”
Publicado 2009
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836“…RESULTS: Using 81 mutant yeast strains, we have evaluated the effect of deleting components of the ADA, COMPASS, CSR, INO80, ISW1, NuA3, NuA4, Mediator, PAF, RSC, SAGA, SAS, SLIK, SWI/SNF and SWR1 transcriptional regulatory complexes on E1A dependent transcription. …”
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837por Sansó, Miriam, Vargas-Pérez, Itzel, Quintales, Luis, Antequera, Francisco, Ayté, José, Hidalgo, Elena“…In a genetic search, we have isolated the histone H3 acetyltransferase Gcn5, a component of the SAGA complex, as being essential for oxidative stress survival and activation of those genes. …”
Publicado 2011
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838“…To test the performance of our algorithm, we have compared it with existing well-known methods, namely PRRP, CLUSTALX, DIALIGN, HMMT, SB_PIMA, ML_PIMA, MULTALIGN, and PILEUP8, and also other methods, based on Genetic Algorithms (GA), such as SAGA, MSA-GA and RBT-GA, by solving a number of benchmark datasets from BAliBase 2.0. …”
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839por Cuenca-Bono, Bernardo, García-Molinero, Varinia, Pascual-García, Pau, Dopazo, Hernan, Llopis, Ana, Vilardell, Josep, Rodríguez-Navarro, Susana“…Sus1/ENY2, a component of the SAGA and TREX-2 complexes, is involved in both transcription and mRNA export. …”
Publicado 2011
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840por Klocko, Andrew D., Rountree, Michael R., Grisafi, Paula L., Hays, Shan M., Adhvaryu, Keyur K., Selker, Eric U.“…GCN-5, a member of the SAGA histone acetyltransferase complex, also shows altered localization in dim-3, raising the possibility that NUP-6 is necessary to localize multiple chromatin complexes following nucleocytoplasmic transport.…”
Publicado 2015
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