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901por Woldegebriel, Rosa, Kvist, Jouni, Andersson, Noora, Õunap, Katrin, Reinson, Karit, Wojcik, Monica H, Bijlsma, Emilia K, Hoffer, Mariëtte J V, Ryan, Monique M, Stark, Zornitza, Walsh, Maie, Cuppen, Inge, van den Boogaard, Marie-Jose´ H, Bharucha-Goebel, Diana, Donkervoort, Sandra, Winchester, Sara, Zori, Roberto, Bönnemann, Carsten G, Maroofian, Reza, O’Connor, Emer, Houlden, Henry, Zhao, Fang, Carpén, Olli, White, Matthew, Sreedharan, Jemeen, Stewart, Murray, Ylikallio, Emil, Tyynismaa, Henna“…For example, all differentially expressed intronless genes were downregulated, including ATXN7L3B, which couples mRNA export to transcription activation by association with the TREX-2 and SAGA complexes. Our results provide insight into the molecular basis behind genotype-phenotype correlations in MCM3AP-associated disease and suggest mechanisms by which GANP defects might alter RNA metabolism.…”
Publicado 2020
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902por Yamashita, Shun, Tokushima, Midori, Nakashima, Tomotaro, E Katsuki, Naoko, Tago, Masaki, Yamashita, Shu-ichi“…METHODS: Data of inpatients of Saga University Hospital with definite IE from September 2007 to August 2017 were retrospectively analyzed. …”
Publicado 2020
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903por Oh, Sang-Ik, Kim, Jong Wan, Kim, Jongho, So, Byungjae, Kim, Bumseok, Kim, Ha-Young“…The isolates were PCR-positive for sla (100%), sagA (100%), and scpA (45.5%), and only 1 isolate amplified the emm gene (stL2764). …”
Publicado 2020
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904por Freitag, Hendrik, de Vries, Rick, Paterno, Marta, Maestri, Simone, Delledonne, Massimo, Thompson, Cameron G, Lamed, Helena, Lambert, Rebekah, Fox, Michael F, Gonzalez, Mariela C, Delocado, Emmanuel D, Sabordo, Marc R, Pangantihon, Clister V, Njunjić, Iva“…NEW INFORMATION: The new species Hydraena dinarica Freitag & de Vries, sp. n. from Durmitor Mt. is described, illustrated and compared in detail to closely-related congeners of the H. saga d'Orchymont, 1930/H. emarginata Rey, 1885 species complex. …”
Publicado 2021
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905por Lee, Sol, Nam, Miyoung, Lee, Ah-Reum, Lee, Jaewoong, Woo, Jihye, Kang, Nam Sook, Balupuri, Anand, Lee, Minho, Kim, Seon-Young, Ro, Hyunju, Choi, Youn-Woong, Kim, Dong-Uk, Hoe, Kwang-Lae“…When we studied the action mechanism of the non-essential target genes using cognate haploid deletion strains, knockout of SAGA-subunit genes caused a down-regulation in erg1 transcription compared to the control strain ED668. …”
Publicado 2021
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906por Rossi, Matthew J., Kuntala, Prashant K., Lai, William K.M., Yamada, Naomi, Badjatia, Nitika, Mittal, Chitvan, Kuzu, Guray, Bocklund, Kylie, Farrell, Nina P., Blanda, Thomas R., Mairose, Joshua D., Basting, Ann V., Mistretta, Katelyn S., Rocco, David J., Perkinson, Emily S., Kellogg, Gretta D., Mahony, Shaun, Pugh, B. Franklin“…We describe TF structural interactions with the genome and cognate cofactors, including nucleosomal and transcriptional regulators RPD3-L, SAGA, NuA4, Tup1, Mediator, and SWI-SNF. Surprisingly, we do not detect TF-TFIID interactions, suggesting that they do not stably occur. …”
Publicado 2021
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907por Sutton, Joshua A. F., Carnell, Oliver T., Lafage, Lucia, Gray, Joe, Biboy, Jacob, Gibson, Josie F., Pollitt, Eric J. G., Tazoll, Simone C., Turnbull, William, Hajdamowicz, Natalia H., Salamaga, Bartłomiej, Pidwill, Grace R., Condliffe, Alison M., Renshaw, Stephen A., Vollmer, Waldemar, Foster, Simon J.“…However, loss of the other three enzymes Atl, SagA and ScaH resulted in clustering dependent attenuation, in a zebrafish embryo, but not a murine, model of infection. …”
Publicado 2021
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908“…H3K4me3-directed H3Ac is mediated by Sgf29, a subunit of the SAGA acetyltransferase complex that interacts with H3K4me3 via a tandem tudor domain (TTD). …”
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909por Orihashi, Ryuzo, Mizoguchi, Yoshito, Imamura, Yoshiomi, Yamada, Shigeto, Monji, Akira“…METHODS: The survey was conducted twice in Kurokawa-cho, Imari, Saga Prefecture, Japan, among people aged 65 years and older. …”
Publicado 2021
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910por Kuang, Xianghong, McAndrew, Michael J., Mustachio, Lisa Maria, Chen, Ying-Jiun C., Atanassov, Boyko S., Lin, Kevin, Lu, Yue, Shen, Jianjun, Salinger, Andrew, Macatee, Timothy, Dent, Sharon Y. R., Koutelou, Evangelia“…Usp22 is the catalytic subunit of the deubiquitylation module in the SAGA histone-modifying complex, which regulates gene transcription. …”
Publicado 2021
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911“…The country has also experienced one of the largest HIV outbreaks associated with the Bulgarian nurse's saga. The effect of the armed conflict on the dynamic spread of HIV is not yet well-known. …”
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912“…METHODS: In the project for H. pylori screening and treatment in Saga Prefecture in 2019, 141 students received the stool H. pylori antigen test as a secondary test. …”
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913por Creutznacher, Robert, Maass, Thorben, Dülfer, Jasmin, Feldmann, Clara, Hartmann, Veronika, Lane, Miranda Sophie, Knickmann, Jan, Westermann, Leon Torben, Thiede, Lars, Smith, Thomas J., Uetrecht, Charlotte, Mallagaray, Alvaro, Waudby, Christopher A., Taube, Stefan, Peters, Thomas“…For structurally closely related HuNoV GII.4 Saga P-dimers a value of about 10(−6 )s(−1) is obtained from ion-exchange chromatography, suggesting essential differences in the role of GCDCA as a cofactor for MNV and HuNoV infection.…”
Publicado 2022
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914“…A 30-m Shuttle Radar Topography Mission (SRTM) Digital Elevation Model (DEM) was used for terrain spatial landslide risk analysis in ArcGis 10.8 and System for Automated Geoscientific Analyses (SAGA) tools. A one-sample t-test in Statistical Package for Social Sciences (SPSS) version 23 was used to analyse the score values on a five-point Likert scale to ascertain the perceived landslide effect on the different disability categories. …”
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915por Kurihara, Yuki, Tashiro, Hiroki, Takahashi, Koichiro, Tajiri, Ryo, Kuwahara, Yuki, Kajiwara, Kokoro, Komiya, Natsuko, Ogusu, Shinsuke, Nakashima, Chiho, Nakamura, Tomomi, Kimura, Shinya, Sueoka‐Aragane, Naoko“…METHODS: A total of 367 patients who underwent EBUS‐GS and were diagnosed with lung cancer in Saga University Hospital were investigated retrospectively. …”
Publicado 2022
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916por Boorstin, Daniel“…En chaque découverte d'importance, que ce soit celle de l'Amérique par Christophe Colomb ou celle de la relativité par Einstein, il voit un épisode d'une biographie. Les héros de la saga qu'il nous raconte sont des hommes dotés d'une insatiable frénésie de connaissance et d'un courage exemplaire pour affronter l'inconnu. …”
Publicado 1986
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917por Cuenca-Bono, Bernardo, García-Molinero, Varinia, Pascual-García, Pau, García-Oliver, Encar, Llopis, Ana, Rodríguez-Navarro, Susana“…In the nucleus, Sus1 is associated to the transcriptional co-activator SAGA and to the NPC associated complex termed TREX2/THSC. …”
Publicado 2010
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918“…Extensive experimental evaluation suggests that (i) our method reduced the running time of a single query on a database of around 300 networks from over 2 days to only 8 h; (ii) our method outperformed the state of the art method Closure Tree and SAGA by a factor of three or more; and (iii) our method successfully identified statistically and biologically significant relationships across networks and organisms. …”
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919por Grassi, Hilda Cristina, García, Lisbette C., Lobo-Sulbarán, María Lorena, Velásquez, Ana, Andrades-Grassi, Francisco A., Cabrera, Humberto, Andrades-Grassi, Jesús E., Andrades, Efrén D. J.“…Conditions of volume (100μl) and parasite density (2-4x10(4) parasites/well, in exponential growth phase), assay time (up to 204min), frame number (11 frames), algorithm and program (RCommander/SAGA) for image processing were selected to test the effect of variable concentrations of benznidazole (0.0195 to 20μg/mL / 0.075 to 76.8μM) at various times (1, 61, 128 and 204min) on the activity of the Biospeckle pattern. …”
Publicado 2016
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920“…Specifically, let-7b and let-7c bind directly and inhibit the mRNAs encoding the DUBs USP42 and USP44, and also the mRNA encoding the adapter protein ATXN7L3, which is part of the DUB module of the SAGA complex. RNF20 knockdown strongly reduces H2Bub1 levels and increases the migration of non-transformed mammary epithelial cells and breast cancer-derived cells. …”
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