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1por Weickhmann, A Katharina, Keller, Heiko, Wurm, Jan P, Strebitzer, Elisabeth, Juen, Michael A, Kremser, Johannes, Weinberg, Zasha, Kreutz, Christoph, Duchardt-Ferner, Elke, Wöhnert, Jens“…In addition, a highly specific riboswitch class recognizes S-adenosylhomocysteine (SAH)—the product of SAM-dependent methyl group transfer reactions—and regulates enzymes responsible for SAH hydrolysis. …”
Publicado 2019
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2por Schmidbauer, Moritz L., Lanz, Hugo, Maskos, Andreas, Putz, Timon, Kunst, Stefan, Dimitriadis, Konstantinos“…As a mean duration of sedation before attempting an awakening trial in patients with unfavorable biomarkers, neurointensivists suggested 4.5 days (SD 1.8) for good-grade SAH and 5.6 days (SD 2.8) for poor-grade SAH, respectively. …”
Publicado 2023
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4“…Acute SAH from a ruptured intracranial aneurysm contributes for 30% of all hemorrhagic strokes. …”
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5por Chaudhry, Shafqat Rasul, Kahlert, Ulf Dietrich, Kinfe, Thomas Mehari, Endl, Elmar, Dolf, Andreas, Niemelä, Mika, Hänggi, Daniel, Muhammad, Sajjad“…Aneurysmal subarachnoid hemorrhage (SAH) is associated with high morbidity and mortality. …”
Publicado 2021
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6“…Subarachnoid hemorrhage (SAH) denotes a serious type of hemorrhagic stroke that often leads to a poor prognosis and poses a significant socioeconomic burden. …”
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8por Darkwah Oppong, Marvin, Bastias, Marcela Jara, Pierscianek, Daniela, Droste, Leonie, Dinger, Thiemo F., Ahmadipour, Yahya, Rauschenbach, Laurèl, Quesada, Carlos, Chihi, Mehdi, Dammann, Philipp, Forsting, Michael, Wrede, Karsten H., Sure, Ulrich, Jabbarli, Ramazan“…This study aimed to analyze the predictors and the impact of SAO in aSAH. METHODS: All aSAH patients from the institutional observational cohort (01/2003–06/2016) were retrospectively reviewed. …”
Publicado 2020
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9por Weiland, Judith, Beez, Alexandra, Westermaier, Thomas, Kunze, Ekkehard, Sirén, Anna-Leena, Lilla, Nadine“…Aneurysmal subarachnoid hemorrhage (aSAH) remains a disease with high mortality and morbidity. …”
Publicado 2021
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10“…Although the number of reported SAH-domains is steadily increasing, genome-wide analyses of SAH-domains in eukaryotic genomes are still missing. …”
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11The Role of Arterioles and the Microcirculation in the Development of Vasospasm after Aneurysmal SAHpor Naraoka, Masato, Matsuda, Naoya, Shimamura, Norihito, Asano, Kenichiro, Ohkuma, Hiroki“…Recent studies have focused on microcirculatory disturbance, such as microthrombosis and arteriolar constriction, as a factor affecting cerebral ischemia after SAH. Reports detecting microthrombosis and arteriolar constriction will be reviewed, and the role of the microcirculation on cerebral ischemia during vasospasm after SAH will be discussed.…”
Publicado 2014
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12por Kamp, Marcel A., Dibué, Maxine, Sommer, Clemens, Steiger, Hans-Jakob, Schneider, Toni, Hänggi, Daniel“…A valid murine SAH injection model is not yet available but would be the prerequisite for further transgenic studies assessing the mechanisms following SAH. …”
Publicado 2014
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13por Lapteva, K, Sazonova, O, Podlepich, V, Troshina, E, Savin, I, Goryachev, A, Sokolova, E, Tyurina, A, Vasil'chenko, VEnlace del recurso
Publicado 2015
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14por Kunze, Ekkehard, Lilla, Nadine, Stetter, Christian, Ernestus, Ralf-Ingo, Westermaier, Thomas“…BACKGROUND: To analyze whether magnesium has a neuroprotective effect during episodes that indicate a critical brain perfusion after aneurysmal subarachnoid hemorrhage (SAH). METHODS: 107 patients with aSAH were randomized to continuously receive intravenous magnesium sulfate with target serum levels of 2.0 – 2.5 mmol/l (n = 54) or isotonic saline (n = 53). …”
Publicado 2018
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16por Torné, Ramon, Culebras, Diego, Sanchez-Etayo, Gerard, García-García, Sergio, Muñoz, Guido, Llull, Laura, Amaro, Sergio, Heering, Christian, Blasco, Jordi, Zavala, Elizabeth, Enseñat, Joaquim“…Delayed cerebral ischemia (DCI) is a dreadful complication present in 30% of subarachnoid hemorrhage (SAH) patients. DCI prediction and prevention are burdensome in poor grade SAH patients (WFNS 4–5). …”
Publicado 2020
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17por Jarocka-Karpowicz, Iwona, Syta-Krzyżanowska, Anna, Kochanowicz, Jan, Mariak, Zenon Dionizy“…Subarachnoid hemorrhage (SAH) accounts for 3% of all strokes. As more and more data indicates the role of oxidative stress in acute brain damage caused by SAH, an attempt was made to correlate the clinical status of patients with systemic level of antioxidants and lipid peroxidation products. …”
Publicado 2020
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18“…While most SAM riboswitches strongly discriminate between SAM and SAH, the SAM/SAH riboswitch responds to both ligands with similar apparent affinities. …”
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19por Rhim, Ha-Young, Won, Sae-Yeon, Kashefiolasl, Sepide, Brawanski, Nina, Hattingen, Elke, Berkefeld, Joachim, Seifert, Volker, Konczalla, Juergen“…We evaluated the impact of infection with MDROs on outcomes in patients with subarachnoid hemorrhage (SAH). A single-center retrospective analysis of SAH cases involving patients treated in the neuro-ICU was performed. …”
Publicado 2021
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