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  1. 541
    “…S-adenosylmethionine (SAM)-dependent methyltransferases regulate a wide range of biological processes through the modification of proteins, nucleic acids, polysaccharides, as well as various metabolites. …”
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    Structural and functional characterization of the TYW3/Taw3 class of SAM-dependent methyltransferases
  2. 542
    “…This study demonstrates that aptamers conjugated to an oligopeptide self-assembled monolayer (SAM) can be used to selectively trap human hepatic cancer cells from cell mixtures containing normal human hepatocytes or human fibroblasts. …”
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    Catch-and-Release of Target Cells Using Aptamer-Conjugated Electroactive Zwitterionic Oligopeptide SAM
  3. 543
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    A B(12)-dependent radical SAM enzyme involved in Oxetanocin-A biosynthesis
  4. 544
    “…[Image: see text] Pyruvate formate-lyase activating enzyme (PFL-AE) is a radical S-adenosyl-l-methionine (SAM) enzyme that installs a catalytically essential glycyl radical on pyruvate formate-lyase. …”
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    Monovalent Cation Activation of the Radical SAM Enzyme Pyruvate Formate-Lyase Activating Enzyme
  5. 545
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    Hydrogen Peroxide-Based Fluorometric Assay for Real-Time Monitoring of SAM-Dependent Methyltransferases
  6. 546
    “…We evaluate several commercially available electrodes which could be suitable for PoC testing with different SAM layers and show that electrode selection also plays an important role in overall biosensor performance.…”
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    SAM Composition and Electrode Roughness Affect Performance of a DNA Biosensor for Antibiotic Resistance
  7. 547
    “…Importantly, we identified a "hypermethylated cell" state as evidenced by an accumulation of S-adenosyl-homocysteine (SAH) and a further reduction of S-adenosylmethionine (SAM) in the hPheo1 SDHB knock out cells compared to the wild-type cells. …”
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    SUN-LB053 Metabolic Interaction of SAH and SAM in hPheo1 Cells
  8. 548
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    Asymmetric Injection in Organic Transistors via Direct SAM Functionalization of Source and Drain Electrodes
  9. 549
    “…CONCLUSIONS: The potential of this methodology is demonstrated with four genome functional annotations performed in merlin, an in-house user-friendly computational framework for genome-scale metabolic annotation and model reconstruction. For that, SamPler was implemented as a new plugin for the merlin tool. …”
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    SamPler – a novel method for selecting parameters for gene functional annotation routines
  10. 550
    por Sajwan, Suresh, Mannervik, Mattias
    Publicado 2019
    “…To date, the most efficient dCas9-based activator is the Synergistic Activation Mediator (SAM) system whereby transcription activation domains are directly fused to dCas9 as well as tethered through MS2 loops engineered into the gRNA. …”
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    Gene activation by dCas9-CBP and the SAM system differ in target preference
  11. 551
    “…Here, we characterize a SAM-I riboswitch (SAM-I(Xcc)) from the Xanthomonas campestris that regulates methionine synthesis via the met operon. …”
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    A SAM-I riboswitch with the ability to sense and respond to uncharged initiator tRNA
  12. 552
    “…The RNA-binding protein Sam68 regulates differentiation processes by modulating splicing, polyadenylation, and stability of select transcripts. …”
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    Sam68 splicing regulation contributes to motor unit establishment in the postnatal skeletal muscle
  13. 553
    “…For this purpose, we apply two different methodologies based on linear social accounting matrix (SAM) models. The linkages show that many bioeconomy products have the potential to promote the rest of the economy and the values of some product multipliers become more significant due to their import dependence. …”
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    The Role of the Foreign Sector in the Spanish Bioeconomy: Two Approaches Based on SAM Linear Models
  14. 554
    “…BACKGROUND: SAM is used as surgical prophylaxis during OLT due to its broad spectrum activity against Gram-positive,-negative and anaerobic pathogens. …”
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    1317. Pharmacokinetics (PK) of Ampicillin-Sulbactam (SAM) during Orthotopic Liver Transplantation (OLT)
  15. 555
    “…This can be achieved using S‐adenosyl‐l‐methionine (SAM)‐dependent methyltransferases and SAM analogs. …”
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    Directed Evolution of a Halide Methyltransferase Enables Biocatalytic Synthesis of Diverse SAM Analogs
  16. 556
    “…It is annotated as a cobalamin-dependent radical S-adenosylmethionine (SAM) methylase; however, TsrM does not reductively cleave SAM to the universal 5ʹ-deoxyadenosyl 5ʹ-radical intermediate, a hallmark of radical-SAM (RS) enzymes. …”
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    Structural basis for non-radical catalysis by TsrM, a radical-SAM methylase
  17. 557
    “…SAMS enhances the production of bee products, creates jobs (particularly youths/women), triggers investments, and establishes knowledge exchange through networks and initiated partnerships.…”
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    Smart apiculture management services for developing countries—the case of SAMS project in Ethiopia and Indonesia
  18. 558
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    Expression and analysis of the SAM-dependent RNA methyltransferase Rsm22 from Saccharomyces cerevisiae
  19. 559
    “…The olanzapine component of OLZ/SAM was bioequivalent to branded olanzapine (Zyprexa); adjunctive OLZ/SAM had no clinically significant effects on lithium or valproate pharmacokinetics. …”
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    An Evidence-Based Review of OLZ/SAM for Treatment of Adults with Schizophrenia or Bipolar I Disorder
  20. 560
    “…[Image: see text] Peptide-based self-assembled monolayers (SAMs) are well known to be crucial for biocompatible surface formation on inorganic substrates applied for implants, biosensors, or tissue engineering. …”
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    Odd–Even Effect in Peptide SAMs—Competition of Secondary Structure and Molecule–Substrate Interaction
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