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  1. 661
    “…We report here the use of the pSAM2 site-specific recombination system to delete antibiotic resistance cassettes used in gene replacement experiments or to create large genomic deletions. …”
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    Marker-Free Genome Engineering in Amycolatopsis Using the pSAM2 Site-Specific Recombination System
  2. 662
    “…Previous large-scale proteomic studies identified the RNA binding protein Sam68 as a putative target of the ATM kinase. Herein, we demonstrate that ATM phosphorylates Sam68 upon DNA damage induction, and this post-translational modification regulates both the signaling function of Sam68 in the initial phase of the DNA damage response and its RNA processing activity. …”
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    DNA Damage Regulates the Functions of the RNA Binding Protein Sam68 through ATM-Dependent Phosphorylation
  3. 663
    por Kachigan, Sam Kash
    Publicado 1991
    Libro
    Multivariate statistical analysis : a conceptual introduction /
  4. 664
    por Ho, Sam P. S.
    Publicado 1980
    Libro
    Small-scale enterprises in Korea and Taiwan /
  5. 665
    Libro
    Radical behaviorism : Willard Day on psychology and philosophy
  6. 666
    por Banks, Samuel Wallace 1905-
    Publicado 1953
    Libro
    An atlas of surgical exposures of the extremities
  7. 667
    Libro
    Crónicas de motel
  8. 668
    Publicado 1994
    Libro
    Developmental toxicology /
  9. 669
    “…Here we develop a strategy to track the structural change of RNAs during transcription at single-nucleotide and single-molecule resolution and use it to monitor individual transcripts of the SAM-VI riboswitch (riboSAM) as transcription proceeds, observing co-existence of five states in riboSAM. …”
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    Observation of structural switch in nascent SAM-VI riboswitch during transcription at single-nucleotide and single-molecule resolution
  10. 670
    “…This work identifies the first SAM-dependent reaction catalyzed by a DUF692 enzyme complex, further expanding the repertoire of remarkable reactions catalyzed by these enzymes. …”
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    Macrocyclization and Backbone Rearrangement During RiPP Biosynthesis by a SAM-Dependent Domain-of-Unknown-Function 692
  11. 671
    “…In the current study, we show that the combinational treatment with SAM-competitive EZH2 inhibitors leads to platinum resistance due to increased platinum efflux. …”
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    SAM-Competitive EZH2-Inhibitors Induce Platinum Resistance by EZH2-Independent Induction of ABC-Transporters
  12. 672
    “…Overexpression of the tylosin efflux gene tlrC, the cluster-situated S-adenosyl methionine (SAM) synthetase gene metK(cs), the SAM biosynthetic genes adoK(cs)-metF(cs), or the pathway-specific activator gene tylR enhanced tylosin production by 18%, 12%, 11%, and 11% in the respective engineered strains TLPH08-2, TLPH09, TLPH10, and TLPH12. …”
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    Enhancing tylosin production by combinatorial overexpression of efflux, SAM biosynthesis, and regulatory genes in hyperproducing Streptomyces xinghaiensis strain
  13. 673
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    Effects of gastrodin on the expression of brain aging‐related genes in SAM/P‐8 mice based on network pharmacology
  14. 674
    “…Alternative splicing in the 3′UTR of mammalian genes plays a crucial role in diverse biological processes, including cell differentiation and development. SAM68 is a key splicing regulator that controls the diversity of 3′UTR isoforms through alternative last exon (ALE) selection. …”
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    Neuronal SAM68 differentially regulates alternative last exon splicing and ensures proper synapse development and function
  15. 675
    por Cochrane, Alan
    Publicado 2009
    “…Two recent publications have explored the mechanisms by which a mutant of the host protein Sam68 blocks HIV-1 structural protein synthesis and expands its activity to encompass Nef. …”
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    Inhibition of HIV-1 gene expression by Sam68ΔC: multiple targets but a common mechanism?
  16. 676
    “…Nuclear Sam68 protein is concentrated within subnuclear organelles called SLM/Sam68 Nuclear Bodies (SNBs), which also contain some other splicing regulators, signalling components and nucleic acids. …”
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    Proteomic identification of heterogeneous nuclear ribonucleoprotein L as a novel component of SLM/Sam68 Nuclear Bodies
  17. 677
    “…The association of the TOB/SAM complex with contact sites depends on the presence of Fcj1. …”
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    The C-terminal domain of Fcj1 is required for formation of crista junctions and interacts with the TOB/SAM complex in mitochondria
  18. 678
    “…Unlike DNA photolyases, SP lyase belongs to the emerging superfamily of radical S-adenosyl-l-methionine (SAM) enzymes and uses a [4Fe–4S](1+) cluster and SAM to initiate the repair reaction. …”
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    Structural insights into recognition and repair of UV-DNA damage by Spore Photoproduct Lyase, a radical SAM enzyme
  19. 679
    “…A 9G DNAChip obtained by allowing the formation of a self-assembled monolayer (SAM) of oligonucleotides appended with nine consecutive guanines on the chip surface has been applied in the detection of biomarkers. …”
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    9G DNAChip Technology: Self-Assembled Monolayer (SAM) of ssDNA for Ultra-Sensitive Detection of Biomarkers
  20. 680
    “…Our results demonstrate that Sam68 plays an essential role in the induction and maintenance of CD25 in T cells. …”
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    Sam68 modulates the promoter specificity of NF-κB and mediates expression of CD25 in activated T cells
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