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741por Zhang, Qian, Wang, Junsong, Liao, Shanting, Li, Pei, Xu, Dingqiao, Lv, Yan, Yang, Minghua, Kong, Lingyi“…These results complemented with neurobehavioral evaluations, cerebral infarct assessments, biochemical evaluations, histological inspections and immunohistochemistry observations strongly demonstrated that HLJDD with optimal proportion of 6 (Rhizoma coptidis): 4 (Radix scutellariae): 1 (Cortex phellodendr): 3 (Fructus Gardeniae) had the best efficacy on ischemic stroke, which could be ascribed to its modulation on AA metabolism. …”
Publicado 2017
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742“…The aim of this study was to evaluate the no-observed-adverse-effect-level (NOAEL) of HVC1 (Gamisamhwangsasim-tang, a 30% ethanol extract of a mixture of Pruni Cortex, Scutellariae Radix, Coptidis Rhizoma, and Rhei Rhizoma) and identify its target organs after oral administration to Sprague-Dawley (SD) rats repeatedly for 13 weeks. …”
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743por Zhang, Yufeng, Lyu, Chunming, Fong, Sophia Yui Kau, Wang, Qian, Li, Chenrui, Ho, Nicolas James, Chan, Kay Sheung, Yan, Xiaoyu, Zuo, Zhong“…Potential pharmacokinetic and pharmacodynamic interaction between OS (30 mg/kg) and the selected herb, Radix Scutellariae (RS), at 300–600 mg/kg were carried out on rats. …”
Publicado 2019
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744“…San-Huang-Xie-Xin-Tang (SHXT), composed of Coptidis rhizoma, Scutellariae radix, and Rhei rhizoma, is a traditional Chinese medicine used for complementary and alternative therapy of cardiovascular and neurodegenerative diseases via its anti-inflammatory and antioxidative effects. …”
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745por Sohn, Kook Ho, Jo, Mi Jeong, Cho, Won Joon, Lee, Jong Rok, Cho, Il Je, Kim, Sang Chan, Kim, Young Woo, Jee, Seon Young“…Bojesodok-eum (BSE) is a herbal prescription consisting of Coptidis Rhizoma and Scutellariae Radix as main components. This paper investigated the effects of BSE on the induction of nitric oxide (NO), prostaglandin E(2) (PGE(2)), and proinflammatory cytokines that are caused by lipopolysaccharide (LPS) in murine macrophage cell line and on the paw edema formation in animals. …”
Publicado 2012
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746“…Gegen-Qinlian-Tang (GQT), a popular Chinese medicine prescription, consists of Puerariae Radix, Scutellariae Radix, Coptidis Rhizoma, and Glycyrrhizae Radix. …”
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747por Tan, Lirong, Su, Jiyan, Wu, Dianwei, Yu, Xiaodan, Su, Zuqing, He, Jingjin, Wu, Xiaoli, Kong, Songzhi, Lai, Xiaoping, Lin, Ji, Su, Ziren“…Baicalin (BA) is the principal component of Radix Scutellariae responsible for its pharmacological activity. …”
Publicado 2013
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748por Chen, Man-Tang, Yang, Yan-Jing, Li, Yu-Sang, Li, Xiao-Jun, Zhang, Wei K., Wang, Jin-Ping, Wang, Xu, Tian, Gui-Hua, Tang, He-Bin“…Shengfu oil is a traditional Chinese medicine formula containing 16 ingredients, including Scutellariae radix, Olibanum, and Rehmanniae radix. In this study, we aimed to enhance the wound healing of rabbit full-thickness scalded skin by Shengfu oil and to elucidate its regulatory effects on β-catenin, Dlk1, and COX-2. …”
Publicado 2017
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749por Lai, Nannan, Fu, Xiaoxiao, Hei, Guozhen, Song, Weiwei, Wei, Ran, Zhu, Xiaoxiao, Guo, Qiang, Zhang, Zhen, Chu, Chu, Xu, Ke, Li, Xia“…Baicalin from Radix Scutellariae possesses a wide range of pharmacological and biological activities. …”
Publicado 2022
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750por Huang, Xuemei, Liu, Xiaojing, Lin, Xiaoyu, Yuan, Zhihua, Zhang, Yaozhi, Wang, Zhijia, Pi, Wenmin, Zhao, Haoqiang, Lei, Haimin, Wang, Penglong“…In this paper, taking the herb pair of Coptidis Rhizoma—Scutellariae Radix and its main component berberine—baicalin as examples, the differences and mechanisms of self-assemblies originated from the co-decoction and physical mixture were studied, respectively. …”
Publicado 2022
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751“…Decreased CyA blood concentration has been shown with St John's wort in case reports and, in vivo animal studies, with ginger, liquorice, scutellariae radix, and quercetin. Increased CyA concentration has been reported in patients with grapefruit juice, chamomile, or berberine, and with cannabidiol or resveratrol in animal studies. …”
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752por Han, Sora, Oh, Ki Sook, Yoon, Yoosik, Park, Jeong Su, Park, Yun Sun, Han, Jeong Hye, Jeong, Ae Lee, Lee, Sunyi, Park, Miyoung, Choi, Yeon A, Lim, Jong Seok, Yang, Young“…Target herbal ingredient (THI) is an extract made from two herbs, Scutellariae Radix and Platycodi Radix. It has been developed as a treatment for metabolic diseases such as hyperlipidemia, atherosclerosis, and hypertension. …”
Publicado 2011
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753por Lee, Kyungjin, Kim, Bumjung, Hur, Heseung, Chinannai, Khanita Suman, Ham, Inhye, Choi, Ho-Young“…The present study was designed to evaluate the antihypertensive effect of GaMiSamHwangSaSimTang (HVC1), a 30% ethanol extract of a mixture comprising Pruni Cortex, Scutellariae Radix, Coptidis Rhizoma, and Rhei Rhizoma, on spontaneous hypertensive rats (SHRs). …”
Publicado 2015
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754por Durairajan, Siva Sundara Kumar, Iyaswamy, Ashok, Shetty, Sravan Gopalakrishna, Kammella, Ananth Kumar, Malampati, Sandeep, Shang, Wenbin, Yang, Chuanbin, Song, Juxian, Chung, Sookja, Huang, Jiandong, Ilango, Kaliappan, Han, Quan-Bin, Li, Min“…HLJDT-M is a formulation composed of Rhizoma Coptitis, Cortex Phellodendri and Fructus Gardeniae without Radix Scutellariae. Here, we assessed the efficacy of HLJDT-M on a triple transgenic mouse model of AD (3XTg-AD). …”
Publicado 2017
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755Oroxylin A activates PKM1/HNF4 alpha to induce hepatoma differentiation and block cancer progressionpor Wei, Libin, Dai, Yuanyuan, Zhou, Yuxin, He, Zihao, Yao, Jingyue, Zhao, Li, Guo, Qinglong, Yang, Lin“…Oroxylin A (OA) is the main bioactive flavonoids of Scutellariae radix, which has strong anti-hepatoma effect but low toxicity to normal tissue. …”
Publicado 2017
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756por Cheng, Ping, Wang, Tong, Li, Wei, Muhammad, Ishfaq, Wang, He, Sun, Xiaoqi, Yang, Yuqi, Li, Jiarui, Xiao, Tianshi, Zhang, Xiuying“…Baicalin is extracted from Radix Scutellariae, which possesses anti-inflammation, antioxidant and antibacterial properties. …”
Publicado 2017
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757por Shen, Le, Zhang, Lu-Lu, Li, Hui, Liu, Xiao, Yu, Xiao-Xuan, Hu, Po, Hui, Hui, Guo, Qing-Long, Zhang, Shuai“…Oroxylin A (OA), a naturally occurring monoflavonoid isolated from Scutellariae radix, has previously been reported to inhibit the proliferation of several cancer cell lines. …”
Publicado 2017
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758por Luo, Lu, Jiang, Jingwen, Wang, Cheng, Fitzgerald, Martin, Hu, Weifeng, Zhou, Yumei, Zhang, Hui, Chen, Shilin“…Glycyrrhizae Radix et Rhizome, Scutellariae Radix, and Armeniacae Semen Amarum are the most frequently utilized in clinics, most of which are antipyretic (47, 26.26%), expectorant and cough-suppressing (22, 12.29%), and dampness-resolving (21, 11.73%) from traditional descriptions. …”
Publicado 2020
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759“…Oroxylin A (OrA) is a natural mono-flavonoid that can be extracted from Scutellariae radix. The present study aimed to investigate the potential effects of OrA on interleukin (IL)-1β-induced chondrocytes inflammatory reactions. …”
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760por Chien, Jia-Ying, Lin, Shu-Fang, Chou, Yu-Yau, Huang, Chi-Ying F., Huang, Shun-Ping“…Oroxylin A (OA) (5,7-dihydroxy-6-methoxyflavone) is a bioactive flavonoid extracted from Scutellariae baicalensis Georgi. with various beneficial effects, including anti-inflammatory and neuroprotective effects. …”
Publicado 2021
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