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301por Medawar, E, Djinbachian, R, Popescu Crainic, I, Lakatos, P, Barkun, A, Bernard, E -J, von Renteln, D“…BACKGROUND: The risk of total metachronous advanced neoplasia (TMAN) in patients with serrated lesions (SL) and IBD is unknown. It is also unclear whether colonic inflammation in IBD contributes to serrated neoplasia. …”
Publicado 2023
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305por Shang, Baoshuan, Wang, Lin, Yan, Xingxing, Li, Yanjun, Li, Changhao, Wu, Chaohua, Wang, Tian, Guo, Xiang, Choi, Suk Won, Zhang, Tianru, Wang, Ziying, Tong, Chun-Yip, Oh, Taerin, Zhang, Xiao, Wang, Zhiye, Peng, Xu, Zhang, Xiuren“…Here, we identified SAID1/2 as negative regulators of SERRATE (SE), a core factor in miRNA biogenesis complex (microprocessor). …”
Publicado 2023
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306“…Signaling by the Notch ligands Delta (Dl) and Serrate (Ser) regulates a wide variety of essential cell-fate decisions during animal development. …”
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307por Roberts, Aedan, Nancarrow, Derek, Clendenning, Mark, Buchanan, Daniel D., Jenkins, Mark A., Duggan, David, Taverna, Darin, McKeone, Diane, Walters, Rhiannon, Walsh, Michael D., Young, Bruce W., Jass, Jeremy R., Rosty, Christophe, Gattas, Michael, Pelzer, Elise, Hopper, John L., Goldblatt, Jack, George, Jill, Suthers, Graeme K., Phillips, Kerry, Parry, Susan, Woodall, Sonja, Arnold, Julie, Tucker, Kathy, Muir, Amanda, Drini, Musa, Macrae, Finlay, Newcomb, Polly, Potter, John D., Pavluk, Erika, Lindblom, Annika, Young, Joanne P.“…The recent identification of families with a heritable predisposition to malignancies arising through the serrated pathway (familial serrated neoplasia or Jass syndrome) provides an opportunity to study a subset of familial CRC in which heterogeneity may be greatly reduced. …”
Publicado 2010
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308“…Approximately 7.5% of all colorectal cancers are considered to originate from the alternative, serrated route. Here, we investigate the expression of the c-MYC oncogene and the SIRT1 protein deacetylase by immunohistochemical staining in subgroups of colorectal serrated lesions that were characterized by different molecular alterations. …”
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309por Heigh, Russell I., Yab, Tracy C., Taylor, William R., Hussain, Fareeda T. N., Smyrk, Thomas C., Mahoney, Douglas W., Domanico, Michael J., Berger, Barry M., Lidgard, Graham P., Ahlquist, David A.“…OBJECTIVES: Precursors to 1/3 of colorectal cancer (CRC), serrated polyps have been under-detected by screening due to their inconspicuous, non-hemorrhagic, and proximal nature. …”
Publicado 2014
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310por Kurihara, Hiroyoshi, Maruyama, Reo, Ishiguro, Kazuya, Kanno, Shinichi, Yamamoto, Itaru, Ishigami, Keisuke, Mitsuhashi, Kei, Igarashi, Hisayoshi, Ito, Miki, Tanuma, Tokuma, Sukawa, Yasutaka, Okita, Kenji, Hasegawa, Tadashi, Imai, Kohzoh, Yamamoto, Hiroyuki, Shinomura, Yasuhisa, Nosho, Katsuhiko“…Regarding premalignant lesions, negative EZH2 expression was frequently detected in sessile serrated adenomas/polyps (SSA/Ps) (76%; P < 0.0001) compared with hyperplastic polyps, traditional serrated adenomas, and non-serrated adenomas (25–36%). …”
Publicado 2016
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311por Väyrynen, Juha P., Mutt, Shivaprakash J., Herzig, Karl-Heinz, Väyrynen, Sara A., Kantola, Tiina, Karhu, Toni, Karttunen, Tuomo J., Klintrup, Kai, Mäkelä, Jyrki, Mäkinen, Markus J., Tuomisto, Anne“…Interestingly, among the patients mismatch repair deficiency, serrated morphology, and high body mass index associated with lowest serum 25(OH)D levels. …”
Publicado 2016
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312“…The concept of CIMP as a molecular carcinogenesis mechanism was consolidated by the identification of the serrated neoplasia pathway, in which CIMP participates in the initiation and progression of serrated adenomas. …”
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313por Lewitowicz, Piotr, Gluszek, Stanislaw, Koziel, Dorota, Horecka-Lewitowicz, Agata, Chrapek, Magdalena, Wolak, Przemyslaw, Klusek, Justyna, Nasierowska-Guttmejer, Anna“…In addition, we found a presence of micro-serration foci more often within tubular adenomas, where focal MSI took place more often. …”
Publicado 2017
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314“…Patient: Male, 66 Final Diagnosis: Serrated polyposis syndrome Symptoms: Positive fecal occult blood test Medication: — Clinical Procedure: — Specialty: Gastroenterology and Hepatology OBJECTIVE: Unusual setting of medical care BACKGROUND: Serrated polyposis syndrome (SPS) is characterized by numerous hyperplastic polyps and sessile serrated adenoma/polyp (SSA/P) in the large intestine. …”
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315por Yoon, Hyuk, Kim, Nayoung, Park, Ji Hyun, Kim, Yong Sung, Lee, Jongchan, Kim, Hyoung Woo, Choi, Yoon Jin, Shin, Cheol Min, Park, Young Soo, Lee, Dong Ho, Jung, Hyun Chae“…BACKGROUND: Studies on gut microbiota regarding colorectal carcinogenesis, including sessile serrated adenoma (SSA), have been scarce. The aim of this study is to investigate the role of mucosa-associated gut microbiota in the colorectal carcinogenesis. …”
Publicado 2017
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316por Ogawa, Yushi, Kudo, Shin-ei, Mori, Yuichi, Ikehara, Nobunao, Maeda, Yasuharu, Wakamura, Kunihiko, Misawa, Masashi, Kudo, Toyoki, Hayashi, Takemasa, Miyachi, Hideyuki, Katagiri, Atsushi, Ishida, Fumio, Inoue, Haruhiro“…BACKGROUND AND STUDY AIMS: Recent studies that used magnifying chromoendoscopy and endocytoscopy (EC) to investigate endoscopic features of sessile serrated adenoma/polyps (SSA/Ps) suggested that a dilated crypt opening was an important indicator of SSA/Ps. …”
Publicado 2017
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317por Sato, Koki, Banshodani, Masataka, Nishihara, Masahiro, Nambu, Junko, Kawaguchi, Yasuo, Shimamoto, Fumio, Dohi, Kiyohiko, Sugino, Keizo, Ohdan, Hideki“…INTRODUCTION: Although appendicitis is a common disease, appendicitis concurrent with liver abscesses and sessile serrated adenoma/polyp (SSA/P) is rare. PRESENTATION OF CASE: A 69-year-old man presented with symptoms of abdominal pain and fever. …”
Publicado 2017
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318por Bond, Catherine E., Liu, Cheng, Kawamata, Futoshi, McKeone, Diane M., Fernando, Winnie, Jamieson, Saara, Pearson, Sally-Ann, Kane, Alexandra, Woods, Susan L., Lannagan, Tamsin R. M., Somashekar, Roshini, Lee, Young, Dumenil, Troy, Hartel, Gunter, Spring, Kevin J., Borowsky, Jennifer, Fennell, Lochlan, Bettington, Mark, Lee, Jason, Worthley, Daniel L., Leggett, Barbara A., Whitehall, Vicki L. J.“…Colorectal cancer is a major cause of cancer death and approximately 20% arises within serrated polyps, which are under-recognized and poorly understood. …”
Publicado 2018
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319“…The south-west Palaearctic Graphipterus serrator group is revised. The systematic concept of the G. serrator group has undergone many changes during the last two centuries, and several different classifications have been published in recent decades. …”
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320por García-Solano, José, Turpin, María C., Torres-Moreno, Daniel, Huertas-López, Francisco, Tuomisto, Anne, Mäkinen, Markus J., Conesa, Ana, Conesa-Zamora, Pablo“…BACKGROUND: Altered methylation patterns are driving forces in colorectal carcinogenesis. The serrated adenocarcinoma (SAC) and sporadic colorectal carcinoma showing histological and molecular features of microsatellite instability (hmMSI-H) are two endpoints of the so-called serrated pathological route sharing some characteristics but displaying a totally different immune response and clinical outcome. …”
Publicado 2018
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