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961por Zhang, Bei-ying, Wang, Bing-yun, Li, Shao-chuan, Luo, Dong-zhang, Zhan, Xiaoshu, Chen, Sheng-feng, Chen, Zhi-sheng, Liu, Can-ying, Ji, Hui-qin, Bai, Yin-shan, Li, Dong-sheng, He, Yang“…On the X-ray images, there was no improvement in the serrate defect of the ventral cortex of the patella. …”
Publicado 2018
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962por Bujanda-Miguel, Gabriela, Martínez-Roca, Alejandro, García-Heredia, Anabel, Guill-Berbegal, David, Roche, Enrique, Jover, Rodrigo“…METHODS: A case-control pilot study was carried out with a sample of 38 individuals, including 23 cases with more than 10 adenomatous or serrated polyps from the national multicenter project EPIPOLIP and 15 healthy controls with normal colonoscopy. …”
Publicado 2023
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963“…While HES1 expression is normal in benign hyperplastic polyps and normal colon tissue, HES1 expression is often lost in sessile serrated adenomas/polyps (SSAs/SSPs) and colorectal cancers (CRCs) such as those right-sided CRCs that commonly harbor BRAF or KRAS mutations. …”
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964por Sajibu, Sija, Sonder, Emanuel, Tiwari, Amit, Orjuela, Stephany, Parker, Hannah R., Frans, Olivier The, Gubler, Christoph, Marra, Giancarlo, Robinson, Mark D.“…METHODS: We used targeted bisulfite sequencing to validate these 990 potential biomarkers in 59 preCRC tissue samples (41 conventional adenomas, 18 sessile serrated lesions), each with a patient-matched normal mucosal sample. …”
Publicado 2023
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965por Jung, Yoon Suk“…Surveillance recommendations for patients with serrated polyps (SPs) are limited. Although the USMSTF guidelines provide specific recommendations for patients who have undergone SPs removal, these are weak and based on very lowquality evidence. …”
Publicado 2023
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966por Vilkoite, Ilona, Tolmanis, Ivars, Abu Meri, Hosams, Polaka, Inese, Mezmale, Linda, Lejnieks, Aivars“…In addition, the ≥50-year age group had increased prevalence of serrated polyps and differing adenoma manifestations. …”
Publicado 2023
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967por Bhattacharya, Debasish“…The divided halves can easily be brought out by serrated crocodile forceps. This nuclear management can be safely performed through a smaller sclerocorneal flap valve incision where the corneal valve action is retained within the limbus without sutures, and the endothelium or the incision is not disturbed. …”
Publicado 2009
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968“…Gain and loss of mir-8 provoked developmental defects reminiscent of impaired Notch signalling and we demonstrated that miR-8 directly inhibits Notch ligand Serrate. Likewise, miR-200c and miR-141 directly inhibited JAGGED1, impeding proliferation of human metastatic prostate cancer cells. …”
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969por Munang'andu, Hetron Mweemba, Chembensofu, Mweelwa, Siamudaala, Victor M., Munyeme, Musso, Matandiko, Wigganson“…The surface cuticle was made of transverse striations which gave the worms a characteristic serrated appearance. Although the calves showed signs of kerato-conjunctivitis, the major pathological change observed was corneal opacity. …”
Publicado 2011
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970“…Subnetwork analysis unraveled some novel regulatory cascades, such as the feedback regulation mediated by miR161, the potential self-regulation of the genes miR172, miR396, miR398 and miR860, and the miR863-guided cleavage of the SERRATE transcript. Our bioinformatics survey expanded the organ-specific miRNA–target list in Arabidopsis, and could deepen the biological view of the miRNA expression and their regulatory roles.…”
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971por Hancock, Shawn, Bowman, Erik, Prabakaran, Jyothiprashanth, Benson, Mark, Agni, Rashmi, Pfau, Patrick, Reichelderfer, Mark, Weiss, Jennifer, Gopal, Deepak“…For lower GI tract pathology i-scan assisted in diagnosis or therapy of right-sided serrated adenomas, flat tubular adenoma, rectal adenocarcinoma, anal squamous cell cancer, solitary rectal ulcer, and radiation proctitis. …”
Publicado 2012
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972por Ben Chaabane, Samir, Liu, Renyi, Chinnusamy, Viswanathan, Kwon, Yerim, Park, Joo-hyuk, Kim, Seo Yeon, Zhu, Jian-Kang, Yang, Seong Wook, Lee, Byeong-ha“…In Arabidopsis, DICER-LIKE1 (DCL1), HYPONASTIC LEAVES 1, SERRATE, HUA ENHANCER1 and HASTY are involved in processing of primary miRNAs (pri-miRNAs) to yield precursor miRNAs (pre-miRNAs) and eventually miRNAs. …”
Publicado 2013
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973“…In this paper, we show that the Notch ligands Delta and Serrate are also substrates of Eogt, that mutation of a putative UDP-GlcNAc binding DXD motif greatly reduces enzyme activity, and that Eogt and the cytoplasmic O-GlcNAc transferase Ogt have distinct substrates in Drosophila larvae. …”
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974“…RESULTS: We found a linear increase of female predominance, T, N category, stage, differentiation, absence of luminal necrosis, tumour -infiltrating lymphocytes, Crohn's-like lymphoid reaction, serration and mucin production from the rectum to caecum. …”
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975por Risseeuw, Eddy, Venglat, Prakash, Xiang, Daoquan, Komendant, Kristina, Daskalchuk, Tim, Babic, Vivijan, Crosby, William, Datla, Raju“…In these lines, the rosette and cauline leaf primordia exhibit reiterated serration, and upon flowering produce ectopic meristems that develop into flowers, bract leaves and inflorescences. …”
Publicado 2013
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976por Kwon, Sang Chang, Choi, Sung Won, Choi, Seong Ho, Park, Hee Seung, Lee, Seung Heon, Kim, Bong Gun, Seo, Eun Hee, Jang, Mun, Ryu, Seung Min, Kim, Dong Hyun, Kim, Young Hoon, Ha, Jun Ouk, Lee, Jae Seung“…Histologically, 19 (36%) were adenomatous polyps, and of these, 15 (28%) were tubular adenomas and 4 (8%) were serrated adenomas. As for the polyp detection rate, there was no difference between the expert and the non-expert groups. …”
Publicado 2014
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977por Kim, Mi-Jung, Lee, Eun-Jung, Chun, Sung-Min, Jang, Se-Jin, Kim, Do Sun, Lee, Doo Han, Youk, Eui Gon“…BACKGROUND: Ectopic crypts, defined as abnormally positioned crypts that have lost their orientation toward the muscularis mucosae, have been suggested to be the best defining histologic feature of traditional serrated adenoma (TSA). However, the significance of ectopic crypt formation (ECF) in the distinction between TSA and conventional adenoma (CA) has rarely been studied. …”
Publicado 2014
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978“…The mammalian genome encodes for four Notch paralogs (Notch 1–4), which are activated by three Delta-like (Dll1/3/4) and two Serrate-like (Jagged1/2) ligands. Further, non-canonical Notch ligands such as epidermal growth factor like protein 7 (EGFL7) have been identified and serve mostly as antagonists of Notch signaling. …”
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979“…DNA was isolated from paired normal and tumoral tissues in 78 tubular adenomas (TAs), 34 serrated polyps (SPs), and 100 CRCs. mtMSI, nucleus microsatellite instability (nMSI), KRAS mutation, and BRAF mutation were investigated in these tumors and their statistical analysis was performed. mtMSI was found in 30% of CRCs and 21.4% of precancerous lesions. …”
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980por dos Santos, Carlos Eduardo Oliveira, Perez, Horácio Joaquin, Mönkemüller, Klaus, Malaman, Daniele, Lopes, César Vivian, Pereira-Lima, Júlio Carlos“…Of 100 colorectal lesions, 88 were neoplastic (73 tubular adenomas, 10 tubulovillous adenomas, 1 villous adenoma, 2 serrated adenomas, 2 adenocarcinomas) and 12 were non-neoplastic (hyperplastic polyps). …”
Publicado 2015
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