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138661por Filion, Kristian B, Lix, Lisa M, Yu, Oriana HY, Dell’Aniello, Sophie, Douros, Antonios, Shah, Baiju R, St-Jean, Audray, Fisher, Anat, Tremblay, Eric, Bugden, Shawn C, Alessi-Severini, Silvia, Ronksley, Paul E, Hu, Nianping, Dormuth, Colin R, Ernst, Pierre, Suissa, Samy, Suissa, Samy, Dormuth, Colin R, Hemmelgarn, Brenda R, Quail, Jacqueline, Chateau, Dan, Paterson, J Michael, LeLorier, Jacques, Levy, Adrian R, Ernst,, Pierre, Filion, Kristian B, Lix, Lisa M, Platt,, Robert W, Sketris, Ingrid S“…SETTING: Canadian Network for Observational Drug Effect Studies (CNODES), with administrative healthcare databases from seven Canadian provinces and the United Kingdom, 2013-18. …”
Publicado 2020
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138662por Ayede, Adejumoke Idowu, Ashubu, Oluwakemi Oluwafunmi, Fowobaje, Kayode Raphael, Aboubaker, Samira, Nisar, Yasir Bin, Qazi, Shamim Ahmad, Bahl, Rajiv, Falade, Adegoke Gbadegesin“…They were treated on an outpatient basis with two days of injectable gentamicin and seven days of oral amoxicillin. Among these 81% (584/721) completed treatment; 97% (700/721) were cured, and three deaths were reported (two with critical illness and one with clinical severe infection). …”
Publicado 2021
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138663Bio-guided isolation of anti-leishmanial natural products from Diospyros gracilescens L. (Ebenaceae)por Njanpa, Cyrille Armel N., Wouamba, Steven Collins N., Yamthe, Lauve Rachel T., Dize, Darline, Tchatat, Brice Mariscal T., Tsouh, Patrick Valère F., Pouofo, Michel Nguiam, Jouda, Jean Bosco, Ndjakou, Bruno Lenta, Sewald, Norbert, Kouam, Simeon Fogue, Boyom, Fabrice Fekam“…Further fractionation of this extract led to four (4) fractions of which, the hexane fraction showed the most potent activity (IC(50) = 0.79 μg/mL), and seven (07) compounds that exhibited moderate potency (IC(50) = 13.69–241.71 μM) against L. donovani. …”
Publicado 2021
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138664“…RESULTS: In this study, the spatial patterns of HTC uptake were found to be non-random (Global Moran’s I = 0.074, p value< 0.001). Forty-seven primary clusters were identified that were located in the entire Somali region with a relative likelihood of 1.50 and the Log-Likelihood Ratio of 135.57. …”
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138665por Langer, Thomas, Brioni, Matteo, Guzzardella, Amedeo, Carlesso, Eleonora, Cabrini, Luca, Castelli, Gianpaolo, Dalla Corte, Francesca, De Robertis, Edoardo, Favarato, Martina, Forastieri, Andrea, Forlini, Clarissa, Girardis, Massimo, Grieco, Domenico Luca, Mirabella, Lucia, Noseda, Valentina, Previtali, Paola, Protti, Alessandro, Rona, Roberto, Tardini, Francesca, Tonetti, Tommaso, Zannoni, Fabio, Antonelli, Massimo, Foti, Giuseppe, Ranieri, Marco, Pesenti, Antonio, Fumagalli, Roberto, Grasselli, Giacomo“…Non-Responders had a more severe respiratory failure and died more often in the ICU (65% vs. 38%, p = 0.047). Forty-seven % of patients were defined as Carbon Dioxide Responders. …”
Publicado 2021
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138666por Fan, Juan, Wang, Jianhui, Zhang, Xianhong, He, Ruiyun, He, Shasha, Yang, Mei, Shen, Yujie, Tao, Xiaojun, Zhou, Mei, Gao, Xiong, Hu, Lijun“…Another 33 infants were retrospectively recruited as the reference group. Thirty-seven infants randomized in the first early intervention, then standard care (EI-SC) group performed a 30-day EI during RCT period, while 36 infants allocated to SC-EI group were given EI in the following open phase. …”
Publicado 2021
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138667por Ducarmon, Quinten R., Terveer, Elisabeth M., Nooij, Sam, Bloem, Michelle N., Vendrik, Karuna E. W., Caljouw, Monique A. A., Sanders, Ingrid M. J. G., van Dorp, Sofie M., Wong, Man C., Zwittink, Romy D., Kuijper, Ed J.“…To obtain longitudinal data, faecal samples from residents were collected for at least two time points. Ultimately, twenty-seven residents were included in the study and 93 faecal samples were analysed, of which 27 (29.0%) were MDRO-positive. …”
Publicado 2021
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138668por Liu, Kai, Cai, Feiyu, Liu, Yanshi, Abulaiti, Alimujiang, Ren, Peng, Yusufu, Aihemaitijiang“…The incidence of postoperative ankle OA was 20.8 %, with 19 patients classified as K&L grade 3 and seven patients as grade 4. The top five risk factors included double-level bone transport (OR3.79, P = 0.005), EFI > 50days/cm (OR3.17, P = 0.015), age > 45years (OR2.29, P = 0.032), osteoporosis (OR1.58, P < 0.001), BMI > 25 (OR1.34, P < 0.001). …”
Publicado 2021
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138669por Anderson, Darcy M., Cronk, Ryan, Pak, Emily, Malima, Precious, Fuente, David, Tracy, J. Wren, Mofolo, Innocent, Kafanikhale, Holystone, Hoffman, Irving, Bartram, Jamie“…We developed frameworks of essential expenses required to provide EHS and conducted an ex-post financial analysis of EHS in a network of medical research and training facilities in Lilongwe, Malawi, serving an estimated 42,000 patients annually through seven outpatient buildings. METHODS: We estimated the cost of providing the following EHS: water, sanitation, hygiene, personal protective equipment use at the point of care, waste management, cleaning, laundry, and vector control. …”
Publicado 2021
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138670por Guerin, Emma, Shkoporov, Andrey N., Stockdale, Stephen R., Comas, Joan Colom, Khokhlova, Ekaterina V., Clooney, Adam G., Daly, Karen M., Draper, Lorraine A., Stephens, Niamh, Scholz, Dimitri, Ross, R. Paul, Hill, Colin“…This had the objective of promoting the simultaneous expansion of crAss-like phages on their native hosts. The levels of seven different crAss-like phages expanded during the fermentation, indicating that their hosts were also present in the fermenter. …”
Publicado 2021
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138671por Liang, Peixuan, Wang, Hui, Zhang, Qiuli, Zhou, Kai, Li, Miaomiao, Li, Ruxiang, Xiang, Siqian, Zhang, Ting, Ling, Yinghua, Yang, Zhenglin, He, Guanghua, Zhao, Fangming“…RESULTS: A rice line with short wide grains, CSSL-Z563, was isolated from advanced-generation backcross population (BC(3)F(6)) derived from ‘Xihui 18’ (the recipient parent) and ‘Huhan 3’ (the donor parent). Z563 carried seven segments from ‘Huhan 3’, distributed on chromosomes 3, 7, and 8, with average substitution length of 5.52 Mb. …”
Publicado 2021
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138672por Anderson, Anna M., Comer, Christine, Smith, Toby O., Drew, Benjamin T., Pandit, Hemant, Antcliff, Deborah, Redmond, Anthony C., McHugh, Gretl A.“…Rounds 2 and 3 therefore included 101 items. Seventy-seven of these reached consensus in Round 3. Six items reached consensus amongst patient or professional panellists only in Round 3. …”
Publicado 2021
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138673por Elhadi, Muhammed, Alsoufi, Ahmed, Msherghi, Ahmed, Alshareea, Entisar, Ashini, Aimen, Nagib, Taha, Abuzid, Nada, Abodabos, Sanabel, Alrifai, Hind, Gresea, Eman, Yahya, Wisal, Ashour, Duha, Abomengal, Salma, Qarqab, Noura, Albibas, Amel, Anaiba, Mohamed, Idheiraj, Hanadi, Abraheem, Hudi, Fayyad, Mohammed, Alkilani, Yosra, Alsuwiyah, Suhir, Elghezewi, Abdelwahap, Zaid, Ahmed“…This study assessed the psychological status of participants who were screened for anxiety symptoms using the seven-item Generalized Anxiety Disorder scale (GAD-7). …”
Publicado 2021
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138674por Genc, Diana, Vaičienė-Magistris, Nerija, Zaborskis, Apolinaras, Şaşmaz, Tayyar, Tunç, Aylin Yeniocak, Uluduz, Derya, Wöber, Christian, Wöber-Bingöl, Çiçek, Steiner, Timothy J.“…METHODS: Following the generic protocol for Lifting The Burden’s global schools-based study, this cross-sectional survey administered self-completed structured questionnaires to pupils within classes in 24 nationally representative schools selected from seven regions of the country. Headache diagnostic questions were based on ICHD-3 beta criteria but for the inclusion of undifferentiated headache (UdH; defined as mild headache with usual duration < 1 h). …”
Publicado 2021
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138675por Möhlhenrich, Stephan Christian, Kötter, Florian, Peters, Florian, Kniha, Kristian, Chhatwani, Sachin, Danesh, Gholamreza, Hölzle, Frank, Modabber, Ali“…This resulted in five groups for Class II treatment and seven groups for Class III treatment. RESULTS: In the Class II patients, a statistically significant difference (p ≤ 0.05) between UpEX and moderate MnA was found for facial profile (N′-Prn-Pog’), soft tissue profile (N′-Sn-Pog’), and mentolabial angle (Pog’-B′-Li). …”
Publicado 2021
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138676“…The mean diameter of the tumour was 47.9 mm (range: 10–258 mm). Forty-seven masses were hypoechoic (74.60%). Twenty-eight masses had posterior echo attenuation, 22 masses exhibited abundant Doppler flow signals (34.92%), and one patient had ascites (1.59%). …”
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138677por Chastin, Sebastien F. M., Abaraogu, Ukachukwu, Bourgois, Jan G., Dall, Philippa M., Darnborough, Jennifer, Duncan, Elaine, Dumortier, Jasmien, Pavón, David Jiménez, McParland, Joanna, Roberts, Nicola J., Hamer, Mark“…METHODS: We conducted a systemic review and meta-analysis according to PRISMA guidelines. We searched seven databases (MEDLINE, Embase, Cochrane CENTRAL, Web of Science, CINAHL, PsycINFO, and SportDiscus) up to April 2020 for randomised controlled trials and prospective observational studies were included if they compared groups of adults with different levels of physical activity and reported immune system cell count, the concentration of antibody, risk of clinically diagnosed infections, risk of hospitalisation and mortality due to infectious disease. …”
Publicado 2021
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138678por Ramírez-Terrazo, Amaranta, Adriana Montoya, E., Garibay-Orijel, Roberto, Caballero-Nieto, Javier, Kong-Luz, Alejandro, Méndez-Espinoza, Claudia“…Mushroom species indicated as non-edible were collected during 13 ethnomycological expeditions and seven requests. To get an insight into the local knowledge about these mushrooms, we used ethnographic techniques, 91 free listings and 81 semi-structured interviews. …”
Publicado 2021
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138679por Pratt, Arthur G, Siebert, Stefan, Cole, Michael, Stocken, Deborah D, Yap, Christina, Kelly, Stephen, Shaikh, Muddassir, Cranston, Amy, Morton, Miranda, Walker, Jenn, Frame, Sheelagh, Ng, Wan-Fai, Buckley, Christopher D, McInnes, Iain B, Filer, Andrew, Isaacs, John D“…Participants were recruited sequentially to a maximum of seven cohorts of three participants each, designated to receive seliciclib 200 mg, 400 mg, 600 mg, 800 mg, or 1000 mg administered in 200 mg oral capsules. …”
Publicado 2021
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138680por Mikasi, Sello Given, Isaacs, Darren, Chitongo, Rumbidzai, Ikomey, George Mondide, Jacobs, Graeme Brendon, Cloete, Ruben“…The possible impact of NOPs on protein structure caused by HIV-1 CRF02_AG variations was addressed within the context of a 3D model of the HIV-1 IN complex and interaction analysis was performed using PyMol to validate DTG binding to the Wild type and seven mutant structures. RESULTS: We observed 12.8% (37/287) sequences to contain RAMs, with only 1.0% (3/287) of the sequences having major INSTI RAMs: T66A, Q148H, R263K and N155H. …”
Publicado 2021
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