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139301por Hannawi, Suad, Yan, Lixin, Saifeldin, Linda, Abuquta, Alaa, Alamadi, Ahmad, Mahmoud, Sally A., Hassan, Aala, Zhang, Miaomiao, Gao, Cuige, Chen, Yuanxin, Gai, Wenlin, Xie, Liangzhi“…Additional endpoints included GMTs of nAb against Delta (B.1.617.2) and Omicron BA.1 variants on day 180, GMTs against BA.5 on day 28, as well as solicited adverse events (AEs) within seven days, unsolicited AEs within 28 days, and serious AEs, AEs of special interest within 180 days after vaccination. …”
Publicado 2023
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139302por Michalik, Felix, Xie, Min, Eyting, Markus, Heß, Simon, Chung, Seunghun, Geldsetzer, Pascal“…Using this unique natural randomization, we have recently provided evidence from Welsh electronic health record data that HZ vaccination caused a reduction in new dementia diagnoses over a seven-year period. Based on this, we hypothesized that HZ vaccination may have slowed the dementia disease process more generally and, thus, already reduced deaths with dementia as their underlying cause even though the UK’s HZ vaccination program commenced as recently as September 2013. …”
Publicado 2023
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139303por Ndagire, Regina, Wangi, Rachel Nante, Ojiambo, Kevin Ouma, Nangendo, Joanita, Nakku, Juliet, Muyinda, Herbert, Semitala, Fred C.“…METHODS: We conducted a retrospective medical records review; seven key informant interviews (KII) among purposively selected healthcare providers and 12 in-depth interviews (IDI) among clinically stable PLHIV with a mental disorder. …”
Publicado 2023
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139304por Likhtshteyn, Michelle, Marzouk, Evan, Arroyo-Mercado, Fray M, Chawla, Gurasees, Rosengarten, Sabrina, Lerer, Renata, Ojeda-Martinez, Hector, Thor, Savanna“…RESULTS: Two hundred and seven patients met our inclusion criteria. The mean age was 56.13 years, and 58% were males. …”
Publicado 2023
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139305por Wu, Jingsong, He, Youze, Liang, Shengxiang, Liu, Zhizhen, Huang, Jia, Liu, Weilin, Tao, Jing, Chen, Lidian, Chan, Chetwyn C. H., Lee, Tatia M. C.“…RESULTS: Fifty participants were included in the analyses after the exclusion of three dropouts and seven participants with low-quality MRI scans. Significant group × time effects were found on the changes in the MoCA, CAVLT, and Rey CFT recall scores. …”
Publicado 2023
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139306por Terzolo, Massimo, Fassnacht, Martin, Perotti, Paola, Libé, Rossella, Kastelan, Darko, Lacroix, André, Arlt, Wiebke, Haak, Harm Reinout, Loli, Paola, Decoudier, Bénédicte, Lasolle, Helene, Quinkler, Marcus, Haissaguerre, Magalie, Chabre, Olivier, Caron, Philippe, Stigliano, Antonio, Giordano, Roberta, Zatelli, Maria Chiara, Bancos, Irina, Fragoso, Maria Candida Barisson Villares, Canu, Letizia, Luconi, Michaela, Puglisi, Soraya, Basile, Vittoria, Reimondo, Giuseppe, Kroiss, Matthias, Megerle, Felix, Hahner, Stefanie, Kimpel, Otilia, Dusek, Tina, Nölting, Svenja, Bourdeau, Isabelle, Chortis, Vasileios, Ettaieb, Madeleine Hester, Cosentini, Deborah, Grisanti, Salvatore, Baudin, Eric, Berchialla, Paola, Bovis, Francesca, Sormani, Maria Pia, Bruzzi, Paolo, Beuschlein, Felix, Bertherat, Jerome, Berruti, Alfredo“…METHODS: ADIUVO was a multicentre, open-label, parallel, randomised, phase 3 trial done in 23 centres across seven countries. Patients aged 18 years or older with adrenocortical carcinoma and low to intermediate risk of recurrence (R0, stage I–III, and Ki67 ≤10%) were randomly assigned to adjuvant oral mitotane two or three times daily (the dose was adjusted by the local investigator with the target of reaching and maintaining plasma mitotane concentrations of 14–20 mg/L) for 2 years or surveillance alone. …”
Publicado 2023
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139307“…Sixteen cases in the conservative group, seven males and nine females, with an average age of 11.81 ± 1.28 years; sixteen cases in the surgical group, eight males and eight females, with an average age of 11.56 ± 1.15 years. …”
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139308“…METHODS: A total of 610 faecal samples from 122 calves (mean age 37.3 days; mean body weight 79.8 kg) were collected on seven different fattening farms during the first 28 days after the arrival and regrouping of the animals. …”
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139309por Xiao, Wenke, Xu, Yaxin, Baak, Jan P., Dai, Jinrong, Jing, Lijia, Zhu, Hongxia, Gan, Yanxiong, Zheng, Shichao“…The Autodock Vina was utilized for molecular docking, and the Gromacs was utilized for molecular dynamics simulations Furthermore, the survival analysis was performed based on TCGA (The Cancer Genome Atlas) database. RESULTS: Seventy-seven AR components absorbed in blood were obtained. …”
Publicado 2023
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139310por Laudin, Garrick Edouard, Lakha, Atul Baldev, Dullabh, Nishal, Mohanlal, Reena, Jassat, Romana, Waja, Muhammed Faadil, Philip, Vinitha“…HIV seropositivity was reported in seven patients (4.8%) and no HIV results were available in 104 patients (71.2%). …”
Publicado 2023
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139311por Caprio, Massimiliano, Moriconi, Eleonora, Camajani, Elisabetta, Feraco, Alessandra, Marzolla, Vincenzo, Vitiello, Laura, Proietti, Stefania, Armani, Andrea, Gorini, Stefania, Mammi, Caterina, Egeo, Gabriella, Aurilia, Cinzia, Fiorentini, Giulia, Tomino, Carlo, Barbanti, Piero“…METHODS: This a prospective, single center, randomized, controlled study aimed at evaluating the efficacy of a very low-calorie ketogenic diet (VLCKD) compared to a hypocaloric balanced diet (HBD) in migraine prophylaxis in patients affected by high-frequency episodic migraine (HFEM) with a Body Mass Index (BMI) > 27 kg/m(2). Fifty-seven patients were randomly assigned to a VLCKD (group 1) or HBD (group 2). …”
Publicado 2023
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139312por Neumann, Alexander, Ohlei, Olena, Küçükali, Fahri, Bos, Isabelle J., Timsina, Jigyasha, Vos, Stephanie, Prokopenko, Dmitry, Tijms, Betty M., Andreasson, Ulf, Blennow, Kaj, Vandenberghe, Rik, Scheltens, Philip, Teunissen, Charlotte E., Engelborghs, Sebastiaan, Frisoni, Giovanni B., Blin, Oliver, Richardson, Jill C., Bordet, Régis, Lleó, Alberto, Alcolea, Daniel, Popp, Julius, Marsh, Thomas W., Gorijala, Priyanka, Clark, Christopher, Peyratout, Gwendoline, Martinez-Lage, Pablo, Tainta, Mikel, Dobson, Richard J. B., Legido-Quigley, Cristina, Van Broeckhoven, Christine, Tanzi, Rudolph E., ten Kate, Mara, Lill, Christina M., Barkhof, Frederik, Cruchaga, Carlos, Lovestone, Simon, Streffer, Johannes, Zetterberg, Henrik, Visser, Pieter Jelle, Sleegers, Kristel, Bertram, Lars“…Mediation tests indicated that variants in APOE are associated with AD status via processes related to amyloid and tau pathology, while markers in TMEM106B and CHI3L1 are associated with AD only via neuronal injury/inflammation. Additionally, seven loci showed sex-specific associations with AD biomarkers. …”
Publicado 2023
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139313por Behairy, Noha, Gubbi, Sriram, Pascoal, Mateus Guimaraes, Bharadwaj, Ashwin, Wright, Elizabeth C, Abijo, Tomilowo, Vikram, Nayan Uttarkar, Veeraraghavan, Padmasree, Cochran, Craig, Glod, John, Klubo-Gwiezdzinska, Joanna“…Results The study cohort consisted of 51 patients (27 women, 53%) with age at the initial scan 24 ± 17 years and an average primary tumor size of 3.3±2.0 cm. Seven patients presented with sporadic MTC, 12 with MEN2A and 32 with MEN2B. …”
Publicado 2023
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139314por Brondani, Vania B, Griffin, Allison M, Owen, Taylor J, Merriman, Kelly W, Varghese, Jeena M, Jimenez, Camilo, Waguespack, Steven G, Graham, Paul H, Campbell, Matthew T, Hassan, Manal M, Habra, Mouhammed A“…The mean adjusted population ACC incidence rate was 0.104 per 100,000 per year (std = 0.005; 95% CI, 0.092-0.116). Seven counties (6.3%) accounted for 215 (48.0%) cases, with more than 10 cases each (median, 34 cases per county; range, 11-66) and a median standardized incidence ratio (SIR) of 0.1 (range, 0.0-0.9). …”
Publicado 2023
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139315“…Despite escalated intravenous levothyroxine doses for seven days her FT4, FT3 continued to remain undetectable So her LT4 dose was increased to 75 mcg IV daily initially and eventually to 100 mcg IV daily and 125 mcg daily. …”
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139316por Yoshiji, Satoshi, Lu, Tianyuan, Butler-Laporte, Guillaume, Carrasco-Zanini-Sanchez, Julia, Chen, Yiheng, Liang, Kevin, Sunday Willett, Julian Daniel, Su, Chen-Yang, Wang, Shidong, Adra, Darin, Ilbudo, Yann, Takayoshi, Sasako, Forgetta, Vincenzo, Farjoun, Yossi, Zeberg, Hugo, Zhou, Sirui, Machiela, Mitchell, Hultstrom, Michael, Wareham, Nicholas, Timpson, Nicholas J, Mooser, Vincent, Langenberg, Claudia, Richards, Brent“…The integrative analysis identified seven plasma protein mediators, including collagen type VI alpha-3 (COL6A3). …”
Publicado 2023
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139317por Refardt, Julie, Atila, Cihan, Chifu, Irina Oana, Ferrante, Emanuele, Erlic, Zoran, Drummond, Juliana Beaudette, Mantovani, Beatrice, Drexhage, Roosmarijn, Sailer, Clara Odilia, Widmer, Andrea, Felder, Susan, Powlson, Andrew Stephen, Hutter, Nina, Vogt, Deborah, Gurnell, Mark, Rocha, Beatriz, Hofland, Johannes, Beuschlein, Felix, Fassnacht, Martin, Winzeler, Bettina Felicitas, Christ-Crain, Mirjam“…Methods: In this prospective randomized multicentre study conducted between 2018-2022 in seven tertiary medical centres, consecutive patients with cDI and PP underwent diagnostic evaluation with hypertonic saline and arginine stimulation. …”
Publicado 2023
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139318por Isand, Kristina, Feelders, Richard Abraham, Brue, Thierry Christian, Toth, Miklos, Deutschbein, Timo, Reincke, Martin, Krsek, Michal, Santos, Alicia, Demtroder, Frank, Chabre, Olivier, Strasburger, Christian Joseph, Wass, John A H, Webb, Susan M, Maso, Ana Aulinas, Volke, Vallo, Valassi, Elena“…Mean operation rate per patient was 1.42 for the VTE group and 1.2 for no-VTE event group (p=0.0068). Seven (7%) patients died during the follow-up time (for different reasons). …”
Publicado 2023
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139319por Lo, Jaclyn S, Bril, Fernando, Taylor, Anya, Morelli, Nazeen, Ware, Meredith A, Garcia-Reyes, Yesenia, McPhaul, Michael J, Cree, Melanie G“…Mass spectrometry was used to measure intact molecules of II and C-peptide. Seventy-seven adolescent girls with PCOS and obesity who were Tanner 5 and at least 1-year post-menarche were enrolled (age 16.3 ± 1.7 years, BMI 34.9 ± 5.0 kg/m(2)). …”
Publicado 2023
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139320por Kahaly, George Jean, George, Augustine, Steiner, Lisa, Weirauch, Tobias, Henseling, Jil, Frommer, Lara, Wolf, Jan“…The % inhibition and compound concentration showed a sigmoidal relationship, with all seven TSAb positive sera markedly inhibited by SYD5115. …”
Publicado 2023
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