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  1. 140121
    “…MAIN RESULTS AND THE ROLE OF CHANCE: Forty-four potential definitions were inventoried across four definition development initiatives, including the Harbin Consensus Conference Workshop Group and International Committee for Monitoring Assisted Reproductive Technologies, 12 clinical practice guidelines and Cochrane Gynaecology and Fertility Group guidelines. Twenty-seven participants, from 11 countries, contributed to the consensus development meeting. …”
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    Standardizing definitions and reporting guidelines for the infertility core outcome set: an international consensus development study  
  2. 140122
    “…Eight serious adverse events (one with placebo, two with 30 μg, and five with 60 μg) occurred in seven infants within 28 days of any study injection, none of which were deemed related to study treatment. …”
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    Safety and immunogenicity of a parenteral P2-VP8-P[8] subunit rotavirus vaccine in toddlers and infants in South Africa: a randomised, double-blind, placebo-controlled trial
  3. 140123
    “…RESULTS: Among interim survey respondents (N=51: 13 [25%] nurses, 11 [22%] physicians, and 27 [53%] patients), mean rankings of the tool’s seven usability attributes ranged from 3.2 to 4.4 (nurses), 3.7 to 4.5 (physicians), and 3.7 to 4.2 (patients). …”
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    Digital Monitoring and Management of Patients With Advanced or Metastatic Non-Small Cell Lung Cancer Treated With Cancer Immunotherapy and Its Impact on Quality of Clinical Care: Interview and Survey Study Among Health Care Professionals and Patients
  4. 140124
    por Carr, Ewan, Bendayan, Rebecca, Bean, Daniel, Stammers, Matt, Wang, Wenjuan, Zhang, Huayu, Searle, Thomas, Kraljevic, Zeljko, Shek, Anthony, Phan, Hang T. T., Muruet, Walter, Gupta, Rishi K., Shinton, Anthony J., Wyatt, Mike, Shi, Ting, Zhang, Xin, Pickles, Andrew, Stahl, Daniel, Zakeri, Rosita, Noursadeghi, Mahdad, O’Gallagher, Kevin, Rogers, Matt, Folarin, Amos, Karwath, Andreas, Wickstrøm, Kristin E., Köhn-Luque, Alvaro, Slater, Luke, Cardoso, Victor Roth, Bourdeaux, Christopher, Holten, Aleksander Rygh, Ball, Simon, McWilliams, Chris, Roguski, Lukasz, Borca, Florina, Batchelor, James, Amundsen, Erik Koldberg, Wu, Xiaodong, Gkoutos, Georgios V., Sun, Jiaxing, Pinto, Ashwin, Guthrie, Bruce, Breen, Cormac, Douiri, Abdel, Wu, Honghan, Curcin, Vasa, Teo, James T., Shah, Ajay M., Dobson, Richard J. B.
    Publicado 2021
    “…A supplemented model adding eight routinely collected blood and physiological parameters (supplemental oxygen flow rate, urea, age, oxygen saturation, C-reactive protein, estimated glomerular filtration rate, neutrophil count, neutrophil/lymphocyte ratio) improved discrimination (AUC = 0.735; 95% CI 0.715, 0.757), and these improvements were replicated across seven UK and non-UK sites. However, there was evidence of miscalibration with the model tending to underestimate risks in most sites. …”
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    Evaluation and improvement of the National Early Warning Score (NEWS2) for COVID-19: a multi-hospital study
  5. 140125
    “…The most common solicited adverse events were injection site pain (17 [5%] of 375 participants), headache (13 [3%]), fatigue (11 [3%]), fever (nine [2%]), and nausea or vomiting (seven [2%]). All solicited adverse events were mild (43 [69%] of 62) or moderate (19 [31%]) and were more frequent after the first dose. …”
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    Safety and immunogenicity of an inactivated SARS-CoV-2 vaccine, BBV152: a double-blind, randomised, phase 1 trial
  6. 140126
    por Côté, Pierre, Hartvigsen, Jan, Axén, Iben, Leboeuf-Yde, Charlotte, Corso, Melissa, Shearer, Heather, Wong, Jessica, Marchand, Andrée-Anne, Cassidy, J. David, French, Simon, Kawchuk, Gregory N., Mior, Silvano, Poulsen, Erik, Srbely, John, Ammendolia, Carlo, Blanchette, Marc-André, Busse, Jason W., Bussières, André, Cancelliere, Carolina, Christensen, Henrik Wulff, De Carvalho, Diana, De Luca, Katie, Du Rose, Alister, Eklund, Andreas, Engel, Roger, Goncalves, Guillaume, Hebert, Jeffrey, Hincapié, Cesar A., Hondras, Maria, Kimpton, Amanda, Lauridsen, Henrik Hein, Innes, Stanley, Meyer, Anne-Laure, Newell, David, O’Neill, Søren, Pagé, Isabelle, Passmore, Steven, Perle, Stephen M., Quon, Jeffrey, Rezai, Mana, Stupar, Maja, Swain, Michael, Vitello, Andrew, Weber, Kenneth, Young, Kenneth J., Yu, Hainan
    Publicado 2021
    “…Our synthesis included six randomized controlled trials with acceptable or high methodological quality (reported in seven articles). These trials investigated the efficacy or effectiveness of SMT for the management of infantile colic, childhood asthma, hypertension, primary dysmenorrhea, and migraine. …”
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    The global summit on the efficacy and effectiveness of spinal manipulative therapy for the prevention and treatment of non-musculoskeletal disorders: a systematic review of the literature
  7. 140127
    “…SUMMARY ANSWER: Overall, 13 (25.5%) of 51 patients who underwent resection had nonvisualized palpable satellite lesions as small as 2 mm, including seven (14%) who had nonvisualized palpable lesions at or beyond the planned stapler site. …”
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    Nonvisualized palpable bowel endometriotic satellites
  8. 140128
    “…Publication bias was examined by Deek’s funnel plot asymmetry test. RESULTS: Forty-seven studies with 8382 NPC patients (NPC group) and 15,089 individuals without NPC (Control group) were included in this meta-analysis. …”
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    The diagnostic value of EBV-DNA and EBV-related antibodies detection for nasopharyngeal carcinoma: a meta-analysis
  9. 140129
    “…Patients undergoing band ligation and auto-amputation for polyps not amenable to snare polypectomy: Seven patients underwent band ligation and auto-amputation due to serrated polyposis syndrome (one patient) and innumerable polyps, or polyps in difficult locations (extension into diverticula: two patients; terminal ileum: two patients; appendiceal orifice: one patient; anal canal: one patient). …”
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    Safety and efficacy of band ligation and auto-amputation as adjunct to EMR of colonic large laterally spreading tumors, and polyps not amenable to routine polypectomy
  10. 140130
    “…RESULT: Seventy-one thousand seven hundred twenty-four (71, 724) mothers who gave at least one birth were recruited in this study. …”
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    Childbirth at home and associated factors in Ethiopia: a systematic review and meta-analysis
  11. 140131
    “…A total of 926 E. coli isolates from seven layer farms (371 isolates), one white-feather broiler farm (78 isolates) and 17 live poultry markets (477 isolates from yellow-feather broilers) in 10 cities in China, were isolated and analyzed for antibiotic resistance phenotypes and genotypes. …”
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    Prevalence and Antibiotic Resistance Characteristics of Extraintestinal Pathogenic Escherichia coli among Healthy Chickens from Farms and Live Poultry Markets in China
  12. 140132
    “…The primary endpoint was time to clinical improvement of two or more points (seven point scale ranging from 1 [death] to 7 [discharged from hospital]) in the modified intention-to-treat population. …”
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    Sarilumab in patients admitted to hospital with severe or critical COVID-19: a randomised, double-blind, placebo-controlled, phase 3 trial
  13. 140133
    “…The most common adverse event was acute respiratory distress syndrome, reported in seven (8%) patients in each group. Grade 3 adverse events were reported in two (2%) patients in the tocilizumab group and five (6%) patients in the standard care group. …”
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    Tocilizumab plus standard care versus standard care in patients in India with moderate to severe COVID-19-associated cytokine release syndrome (COVINTOC): an open-label, multicentre, randomised, controlled, phase 3 trial
  14. 140134
    por Bowman, Clive E.
    Publicado 2021
    “…A model based upon mechanics is used in a re-analysis of historical acarine morphological work augmented by an extra seven zoophagous mesostigmatid species. This review shows that predatory mesostigmatids do have cheliceral designs with clear rational purposes. …”
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    Feeding design in free-living mesostigmatid chelicerae (Acari: Anactinotrichida)
  15. 140135
    “…One hundred eighteen articles with 128 patient cohorts containing 51,374 patients reporting mortality fulfilled the eligibility criteria and were included in the meta-analysis. SMR from seven autoimmune/inflammatory disease studies was 1.84 (95%CI 1.27,2.41) with I2 70.2 6%. …”
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    Real World Mortality and Specific Causes of Death in Chronic Oral Glucocorticoid Use: A Systematic Review, Meta-Analysis and Meta-Regression
  16. 140136
    “…Most patients had albumin-adjusted serum calcium level in the lower half of reference range (median 2.24 mmol/L [2.14; 2.34]). Seven patients had secondary hyperparathyroidism and one patient had primary hyperparathyroidism, the rest of the patients had PTH levels within the normal range.25(OH)D3 levels showed significant negative correlation with percent of lung involvement (r = -0.36, p<0.05) and positive correlation with SpO2 (r = 0.4, p<0.05). 1,25(OH)2D3 levels correlated positively with 25(OH)D3 levels (r = 0.38, p<0.05) and did not correlate significantly with PTH levels (p>0.05). …”
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    Vitamin D Metabolism Is Significantly Impaired in COVID-19 Inpatients
  17. 140137
    “…Multiple subtypes of AIVs including nine hemagglutinin (HA) and seven neuraminidase (NA) subtypes were isolated form the environmental samples. …”
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    Distribution of avian influenza viruses according to environmental surveillance during 2014–2018, China
  18. 140138
    Publicado 2021
    “…We pooled the data to investigate the stratified effects of blood pressure-lowering treatment in participants with and without prevalent cardiovascular disease (ie, any reports of stroke, myocardial infarction, or ischaemic heart disease before randomisation), overall and across seven systolic blood pressure categories (ranging from <120 to ≥170 mm Hg). …”
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    Pharmacological blood pressure lowering for primary and secondary prevention of cardiovascular disease across different levels of blood pressure: an individual participant-level data meta-analysis
  19. 140139
    “…The majority of adverse events were mild, with the most common event being fever. None of the seven serious adverse events were attributed to the vaccine. …”
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    Efficacy of a low-dose candidate malaria vaccine, R21 in adjuvant Matrix-M, with seasonal administration to children in Burkina Faso: a randomised controlled trial
  20. 140140
    “…RESULTS: We studied 745 patients from 22 countries, who required admission to the ICU and MV from January 14 to December 31, 2020, and presented at least one value of C(RS) within the first seven days of MV. Median (IQR) age was 62 (52–71), patients were predominantly males (68%) and from Europe/North and South America (88%). …”
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    An appraisal of respiratory system compliance in mechanically ventilated covid-19 patients
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