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  1. 140181
    “…Within-group reduction in mosquito infection rate on day 7 was 79·95% (IQR 57·15–100; p=0·0005 for difference from baseline) following dihydroartemisinin–piperaquine only, 100% (98·36–100; p=0·0005) following dihydroartemisinin–piperaquine plus tafenoquine 0·42 mg/kg, 100% (100–100; p=0·0001) following dihydroartemisinin–piperaquine plus tafenoquine 0·83 mg/kg, and 100% (100–100; p=0·0001) following dihydroartemisinin–piperaquine plus tafenoquine 1·66 mg/kg. 55 (69%) of 80 participants had a total of 94 adverse events over the course of the trial; 86 (92%) adverse events were categorised as mild, seven (7%) as moderate, and one (1%) as severe. The most common treatment-related adverse event was mild or moderate headache, which occurred in 15 (19%) participants (dihydroartemisinin–piperaquine n=2; dihydroartemisinin–piperaquine plus tafenoquine 0·42 mg/kg n=6; dihydroartemisinin–piperaquine plus tafenoquine 0·83 mg/kg n=3; and dihydroartemisinin–piperaquine plus tafenoquine 1·66 mg/kg n=4). …”
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    Single low-dose tafenoquine combined with dihydroartemisinin–piperaquine to reduce Plasmodium falciparum transmission in Ouelessebougou, Mali: a phase 2, single-blind, randomised clinical trial
  2. 140182
    “…We enrolled children from seven research centres in South Africa, Uganda, and Zimbabwe. …”
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    Dolutegravir dosing for children with HIV weighing less than 20 kg: pharmacokinetic and safety substudies nested in the open-label, multicentre, randomised, non-inferiority ODYSSEY trial
  3. 140183
    por Belaid, Brahim, Lamara Mahammed, Lydia, Drali, Ouardia, Oussaid, Aida Mohand, Touri, Nabila Souad, Melzi, Souhila, Dehimi, Abdelhak, Berkani, Lylia Meriem, Merah, Fatma, Larab, Zineb, Allam, Ines, Khemici, Ouarda, Kirane, Sonya Yasmine, Boutaba, Mounia, Belbouab, Reda, Bekkakcha, Hadjira, Guedouar, Assia, Chelali, Abdelhakim, Baamara, Brahim, Noui, Djamila, Baaziz, Hadda, Rezak, Radia, Azzouz, Sidi Mohamed, Aichaoui, Malika, Moktefi, Assia, Benhatchi, Redha Mohamed, Oussalah, Meriem, Benaissa, Naila, Laredj, Amel, Bouchetara, Assia, Adria, Abdelkader, Habireche, Brahim, Tounsi, Noureddine, Dahmoun, Fella, Touati, Rabah, Boucenna, Hamza, Bouferoua, Fadila, Sekfali, Lynda, Bouhafs, Nadjet, Aboura, Rawda, Kherra, Sakina, Inouri, Yacine, Dib, Saadeddine, Medouri, Nawel, Khelfaoui, Noureddine, Redjedal, Aicha, Zelaci, Amara, Yahiaoui, Samah, Medjadj, Sihem, Touhami, Tahar Khelifi, Kadi, Ahmed, Amireche, Fouzia, Frada, Imane, Houasnia, Shahrazed, Benarab, Karima, Boubidi, Chahynez, Ferhani, Yacine, Benalioua, Hayet, Sokhal, Samia, Benamar, Nadia, Aggoune, Samira, Hadji, Karima, Bellouti, Asma, Rahmoune, Hakim, Boutrid, Nada, Okka, kamelia, Ammour, Assia, Saadoune, Houssem, Amroun, Malika, Belhadj, Hayet, Ghanem, Amina, Abbaz, Hanane, Boudrioua, Sana, Zebiche, Besma, Ayad, Assia, Hamadache, Zahra, Ouaras, Nassima, Achour, Nassima, Bouchair, Nadira, Boudiaf, Houda, Bekkat-Berkani, Dahila, Maouche, Hachemi, Bouzrar, Zahir, Aissat, Lynda, Ibsaine, Ouardia, Bioud, Belkacem, Kedji, Leila, Dahlouk, Djazia, Bensmina, Manoubia, Radoui, Abdelkarim, Bessahraoui, Mimouna, Bensaadi, Nadia, Mekki, Azzeddine, Zeroual, Zoulikha, Chan, Koon-Wing, Leung, Daniel, Tebaibia, Amar, Ayoub, Soraya, Mekideche, Dalila, Gharnaout, Merzak, Casanova, Jean Laurent, Puel, Anne, Lau, Yu Lung, Cherif, Nacira, Ladj, Samir, Smati, Leila, Boukari, Rachida, Benhalla, Nafissa, Djidjik, Reda
    Publicado 2022
    “…RESULTS: Eight hundred and seven patients with IEI (482 males and 325 females) were enrolled, 9.7% of whom were adults. …”
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    Inborn Errors of Immunity in Algerian Children and Adults: A Single-Center Experience Over a Period of 13 Years (2008–2021)
  4. 140184
    “…METHODS: HPTN 084 was a phase 3, randomised, double-blind, double-dummy, active-controlled, superiority trial in 20 clinical research sites in seven countries in sub-Saharan Africa. Participants were eligible for enrolment if they were assigned female sex at birth, were aged 18–45 years, reported at least two episodes of vaginal intercourse in the previous 30 days, were at risk of HIV infection based on an HIV risk score, and agreed to use a long-acting reversible contraceptive method. …”
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    Cabotegravir for the prevention of HIV-1 in women: results from HPTN 084, a phase 3, randomised clinical trial
  5. 140185
    “…We used version 2 of the Cochrane risk-of-bias tool for randomised trials to assess risk of bias for the primary outcome. RESULTS: Seven trials (6609 participants) were included. A dose-dependent superiority in lowering HbA(1c) was evident with all three tirzepatide doses vs all comparators, with mean differences ranging from −17.71 mmol/mol (−1.62%) to −22.35 mmol/mol (−2.06%) vs placebo, −3.22 mmol/mol (−0.29%) to −10.06 mmol/mol (−0.92%) vs GLP-1 RAs, and −7.66 mmol/mol (−0.70%) to −12.02 mmol/mol (−1.09%) vs basal insulin regimens. …”
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    Management of type 2 diabetes with the dual GIP/GLP-1 receptor agonist tirzepatide: a systematic review and meta-analysis
  6. 140186
    “…In multivariate analysis, seven variables were found to be associated with good QOL among the participants. …”
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    Quality of life and factors associated with a good quality of life among diabetes mellitus patients in northern Thailand
  7. 140187
    “…Data from selected studies relating to Screening, Assessment and Diagnosis of eating disorders were synthesised and are disseminated in the current review. RESULTS: Eighty seven studies were identified, 38% relating to screening and 62% to assessment and diagnosis. …”
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    Screening, assessment and diagnosis in the eating disorders: findings from a rapid review
  8. 140188
    “…The haplotype analysis among 11, 10, 10, and seven SNPs in MT (MT1A, MT2A, MT1M, MT1B, and MT1DP) genes showed that eight (A-C-G-T-C-G-A-G-C-G-C, OR = 4.559; A-C-T-C-C-C-A-G-C-G-C, OR = 5.777; A-C-T-T-C-G-A-G-C-G-C, OR = 4.590; G-A-T-C-C-G-C-G-G-C-C, OR = 4.065; G-A-T-C-G-C-C-G-G-C-C, OR = 4.652; G-A-T-T-C-C-C-G-G-C-C, OR = 0.404; G-C-T-C-C-C-A-G-G-C-C, OR = 1.901; G-C-T-T-C-C-A-G-G-C-C, and OR = 3.810), five (C-G-A-T-C-A-C-C-G-G, OR = 2.032; C-G-A-T-C-G-C-C-G-G, OR = 2.077; G-A-C-T-C-A-C-C-T-G, OR = 0.564; G-G-A-G-C-A-C-C-G-G, OR = 5.466; G-G-A-T-T-A-G-C-G-G, and OR = 0.284), five (A-C-G-T-C-G-A-G-C-C, OR = 2.399; A-C-T-C-C-C-C-T-G-G, OR = 0.259; G-A-T-C-C-C-C-G-G-C, OR = 1.572; G-A-T-C-G-C-C-G-G-C, OR = 0.001; G-C-T-C-G-C-A-G-G-C, and OR = 2.512), and five (A-C-T-C-C-C-G, OR = 0.634; G-A-G-C-C-C-G, OR = 4.047; G-A-T-T-G-C-G, OR = 0.499; G-C-G-T-C-A-G, and OR = 7.299; G-C-T-C-C-A-G, OR = 1.434) haplotypes were significantly associated with pregnancy with chronic hypertension, gestational hypertension, preeclampsia, or preeclampsia superimposed on chronic hypertension and HDP. …”
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    Genetic Variations in Metallothionein Genes and Susceptibility to Hypertensive Disorders of Pregnancy: A Case-Control Study
  9. 140189
    “…The AhR activation potencies of seven PM(2.5)-bound PAHs, reported in the ToxCast database, were strongly correlated with their capabilities of enhancing the migration ability of VSMCs. …”
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    Aryl hydrocarbon receptor activation-mediated vascular toxicity of ambient fine particulate matter: contribution of polycyclic aromatic hydrocarbons and osteopontin as a biomarker
  10. 140190
    “…With regard to the Akt/MK-2206 complex there were three Van der Waals interactions and 12 chemical bonds in which seven residues of Akt were involved with all five rings of the MK-2206 structure. …”
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    COVID-19 liver and gastroenterology findings: An in silico analysis of SARS-CoV-2 interactions with liver molecules
  11. 140191
    “…The questionnaire adopts seven points scoring. The composite reliability of the expression inhibition dimension in this measurement is 0.83, the 95% confidence interval estimated by delta method is [0.81, 0.85], and the composite reliability of cognitive reappraisal dimension is 0.83, and the 95% confidence interval is [0.81, 0.85]. …”
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    EPIDEMIC EVOLUTION UNDIFFERENTIATED POPULATION WITHOUT INTERVENTION AND MARKETING OF ANXIETY SENSITIVITY
  12. 140192
    “…Of the 101,725 routine and 1884 repeat VL tests, 13.8% and 52.9% were non-suppressed, respectively. Only one in seven (1:7) of the non-suppressed routine VL tests had a repeat test after EAC. …”
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    Virological outcomes and risk factors for non-suppression for routine and repeat viral load testing after enhanced adherence counselling during viral load testing scale-up in Zimbabwe: analytic cross-sectional study using laboratory data from 2014 to 2018
  13. 140193
    “…RESULTS: 46 studies were included (14 on incidence, seven on risk factors, 11 on characteristics and short term course, three on longer term outcomes, and 21 on mechanisms). …”
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    Incidence, risk factors, natural history, and hypothesised mechanisms of myocarditis and pericarditis following covid-19 vaccination: living evidence syntheses and review
  14. 140194
    por Plekhanova, Tatiana, Rowlands, Alex V., Evans, Rachael A., Edwardson, Charlotte L., Bishop, Nicolette C., Bolton, Charlotte E., Chalmers, James D., Davies, Melanie J., Daynes, Enya, Dempsey, Paddy C., Docherty, Annemarie B., Elneima, Omer, Greening, Neil J., Greenwood, Sharlene A., Hall, Andrew P., Harris, Victoria C., Harrison, Ewen M., Henson, Joseph, Ho, Ling-Pei, Horsley, Alex, Houchen-Wolloff, Linzy, Khunti, Kamlesh, Leavy, Olivia C., Lone, Nazir I., Marks, Michael, Maylor, Ben, McAuley, Hamish J. C., Nolan, Claire M., Poinasamy, Krisnah, Quint, Jennifer K., Raman, Betty, Richardson, Matthew, Sargeant, Jack A., Saunders, Ruth M., Sereno, Marco, Shikotra, Aarti, Singapuri, Amisha, Steiner, Michael, Stensel, David J., Wain, Louise V., Whitney, Julie, Wootton, Dan G., Brightling, Christopher E., Man, William D-C., Singh, Sally J., Yates, Tom
    Publicado 2022
    “…METHODS: One thousand seventy-seven patients with COVID-19 discharged from hospital between March and November 2020 were recruited. …”
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    Device-assessed sleep and physical activity in individuals recovering from a hospital admission for COVID-19: a multicentre study
  15. 140195
    “…RESULTS: Eighty-six patients were randomized in the original trial. Fifty-seven of those completed the long-term follow-up, 31 of 45 from the No ACR group and 25 of 41 from the ACR group. …”
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    Paper 65: Arthroscopic rotator cuff repair with and without acromioplasty in the treatment of full-thickness rotator cuff tears: long term follow-up of a multicenter, randomized controlled trial
  16. 140196
    “…By percentage, radial tears are seven times more common and posterior root tears are twice as common in lateral meniscus tears. …”
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    Poster 224: Tear Features and Surgical Techniques in 1230 Child and Adolescent Meniscus Repairs: Results from a Prospective, Multicenter Registry
  17. 140197
    “…The prescribed dose was 50 Gy in 25 fractions over five weeks. In IP IMRT, five to seven tangential beams were used for the chest wall, nodal volumes were placed at suitable angles with beam optimization, and calculation was carried out by the analytical anisotropic algorithm. …”
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    Comparison of Dosimetric Parameters and Clinical Outcomes in Inversely Planned Intensity-Modulated Radiotherapy (IMRT) and Field-in-Field Forward Planned IMRT for the Treatment of Breast Cancer
  18. 140198
    “…METHODS: We did an observational cohort study, set in seven Canadian provinces and territories including Ontario, Quebec, British Columbia, Alberta, Nova Scotia, Yukon, and Prince Edward Island. …”
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    Safety of COVID-19 vaccines in pregnancy: a Canadian National Vaccine Safety (CANVAS) network cohort study
  19. 140199
    “…Duration of the intervention was of the six months consecutive for at least 42 h per week (six hours a day, seven days a week). Outcome primary were calcaneus pain (visual analogue scale), Foot Function Index (FFI), Foot Health Status Questionnaire (FHSQ-Br) and 6-min walk test (6MWT). …”
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    Effectiveness of mechanical treatment with customized insole and minimalist flexible footwear for women with calcaneal spur: randomized controlled trial
  20. 140200
    “…RESULTS: Literature search identified seven miRNAs (hsa-let-7a-5p, hsa-miR-9-3p, hsa-miR-22-5p, has-miR-30b-5p, hsa-miR-103-3p, hsa-miR-122-5p and hsa-miR-335-5p) showing consistent dysregulation in infertility across a minimum of four studies. …”
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    Qualitative and quantitative assessment of sperm miRNAs identifies hsa-miR-9-3p, hsa-miR-30b-5p and hsa-miR-122-5p as potential biomarkers of male infertility and sperm quality
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