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  1. 2181
    “…However, no study has investigated whether the presence and severity of NVP may be related to symptom severity in offspring with ASD. …”
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    Symptom severity in autism spectrum disorder is related to the frequency and severity of nausea and vomiting during pregnancy: a retrospective case-control study
  2. 2182
    “…Febrile patients (>12 years) with severe falciparum malaria were randomly assigned to receive acetaminophen (1 g 6–hourly for 72 hours) or no acetaminophen, in addition to intravenous artesunate. …”
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    Acetaminophen as a Renoprotective Adjunctive Treatment in Patients With Severe and Moderately Severe Falciparum Malaria: A Randomized, Controlled, Open-Label Trial
  3. 2183
    “…BACKGROUND: Most existing screening instruments that assess cognition and functioning in dementia suffer from floor effects, limiting their utility in severely demented patients. In 2015, the first author devised a new instrument, The Multimodal Assessment of Capacities in Severe Dementia (MAC-SD), to address this need. …”
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    Validation of the English Version of the Multimodal Assessment of Capacities in Severe Dementia (MAC-SD): A Cognitive and Functional Scale for Use in Severe Dementia
  4. 2184
    “…In this study, a novel compound was identified that increased SMN protein levels in vivo and ameliorated the disease phenotype in severe and intermediate mouse models of SMA.…”
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    Intraperitoneal delivery of a novel drug‐like compound improves disease severity in severe and intermediate mouse models of Spinal Muscular Atrophy
  5. 2185
    “…RESULTS: The patient was a 32-year-old man with severe obesity (Body Mass Index = 35) and heavy smoking (ten cigarettes per day for more than ten years). …”
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    Identification of a novel and heterozygous LMF1 nonsense mutation in an acute pancreatitis patient with severe hypertriglyceridemia, severe obesity and heavy smoking
  6. 2186
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    Reply to Comments on the Study “The Sensitivity, Specificity and Accuracy of Warning Signs in Predicting Severe Dengue, the Severe Dengue Prevalence and its Associated Factors”
  7. 2187
    “…Background: The management of the moderate and severe forms of acute pancreatitis (AP) with necrosis and multiorgan failure remains a challenge. …”
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    Computed Tomography Severity Index vs. Other Indices in the Prediction of Severity and Mortality in Acute Pancreatitis: A Predictive Accuracy Meta-analysis
  8. 2188
    por Park, Se Eun, Toy, Trevor, Cruz Espinoza, Ligia Maria, Panzner, Ursula, Mogeni, Ondari D, Im, Justin, Poudyal, Nimesh, Pak, Gi Deok, Seo, Hyeongwon, Chon, Yun, Schütt-Gerowitt, Heidi, Mogasale, Vittal, Ramani, Enusa, Dey, Ayan, Park, Ju Yeong, Kim, Jong-Hoon, Seo, Hye Jin, Jeon, Hyon Jin, Haselbeck, Andrea, Conway Roy, Keriann, MacWright, William, Adu-Sarkodie, Yaw, Owusu-Dabo, Ellis, Osei, Isaac, Owusu, Michael, Rakotozandrindrainy, Raphaël, Soura, Abdramane Bassiahi, Kabore, Leon Parfait, Teferi, Mekonnen, Okeke, Iruka N, Kehinde, Aderemi, Popoola, Oluwafemi, Jacobs, Jan, Lunguya Metila, Octavie, Meyer, Christian G, Crump, John A, Elias, Sean, Maclennan, Calman A, Parry, Christopher M, Baker, Stephen, Mintz, Eric D, Breiman, Robert F, Clemens, John D, Marks, Florian
    Publicado 2019
    “…However, there is a paucity of data on severe typhoid fever and its associated acute and chronic host immune response and carriage. …”
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    The Severe Typhoid Fever in Africa Program: Study Design and Methodology to Assess Disease Severity, Host Immunity, and Carriage Associated With Invasive Salmonellosis
  9. 2189
    “…Purpose: We sought to identify a MODS score parameter that highly correlates with adverse outcomes and then use this parameter to test the hypothesis that multiple severity-based MODS clusters could be identified after blunt trauma. …”
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    Unsupervised Clustering Analysis Based on MODS Severity Identifies Four Distinct Organ Dysfunction Patterns in Severely Injured Blunt Trauma Patients
  10. 2190
    “…We report a case of multiple episodes of severe hypoglycemia in a non-diabetic patient on treatment with tigecycline for cellulitis following snake bite. …”
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    Tigecycline-Induced Severe Hypoglycemia in a Non-Diabetic Individual: A Case Report and Brief Review of Tigecycline-Induced Severe Hypoglycemia
  11. 2191
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    Male Sex, Severe Obesity, Older Age, and Chronic Kidney Disease Are Associated With COVID-19 Severity and Mortality in New York City
  12. 2192
    “…In addition, we provide several hypotheses for severe COVID-19 and possible therapeutic targets.…”
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    The role of host genetics in susceptibility to severe viral infections in humans and insights into host genetics of severe COVID-19: A systematic review
  13. 2193
    “…All studies comparing clinical data of severe and non‐severe patients of COVID‐19 were included. …”
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    Clinical features, comorbidities, complications and treatment options in severe and non‐severe COVID‐19 patients: A systemic review and meta‐analysis
  14. 2194
    “…The clinical information of 167 patients with severe COVID-19 was analyzed. The median age was 65.0 years. …”
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    The risk factors for mortality of diabetic patients with severe COVID-19: A retrospective study of 167 severe COVID-19 cases in Wuhan
  15. 2195
    “…We aimed to assess the safety and efficacy of standard prophylaxis versus on-demand treatment with rAHF in previously treated Chinese patients with severe/moderately severe hemophilia A. This open-label, sequential, interventional, postapproval study (NCT02170402) conducted in China included patients of any age with hemophilia A with factor VIII (FVIII) level ≤2%. …”
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    Phase 4 Safety and Efficacy Study of Antihemophilic Factor (Recombinant) in Previously Treated Chinese Patients With Severe/Moderately Severe Hemophilia A
  16. 2196
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    Morphological Characteristics of Psoriatic Lesions Affect the Accuracy and Reliability of Severity Assessments: Proposal for New Working Criteria for the Psoriasis Area and Severity Index
  17. 2197
    “…OBJECTIVE: This study was designed to explore the impact of different scoring settings of disease severity on the accuracy of screening by NRS2002. METHODS: Patients with severe COVID-19 who were admitted to our hospital from January 26, 2020, to March 16, 2020, were enrolled in this study. …”
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    Preliminary Exploration of Setting the Disease Severity Score in the Nutritional Risk Screening of Patients with Severe Novel Coronavirus Pneumonia by Applying NRS2002
  18. 2198
    por Arora, Prateek, Neema, Praveen K
    Publicado 2021
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    In response to “Left atrial thrombus in a case of severe aortic stenosis with severe left ventricular dysfunction: An incidental finding on transesophageal echocardiography”
  19. 2199
    “…CONCLUSION: In CAVB dogs, severe bradycardia increases the probability and severity of arrhythmic events by heterogeneously causing electrophysiological instability, which is mainly reflected in an increased spatial, and to a lesser extent temporal, dispersion of repolarization.…”
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    Severe Bradycardia Increases the Incidence and Severity of Torsade de Pointes Arrhythmias by Augmenting Preexistent Spatial Dispersion of Repolarization in the CAVB Dog Model
  20. 2200
    “…BACKGROUND: Multiple organ failure (MOF) may lead to an increased mortality rate of moderately severe (MSAP) or severe acute pancreatitis (SAP). …”
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    Prediction of Multiple Organ Failure Complicated by Moderately Severe or Severe Acute Pancreatitis Based on Machine Learning: A Multicenter Cohort Study
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