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  1. 2281
    “…Severe mental illnesses (SMI), such as schizophrenia and bipolar disorder, are associated with a decrease in life expectancy of up to two decades compared with the general population, with cardiovascular disease as the leading cause of death. …”
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    Coronary Artery Disease in Patients with Severe Mental Illness
  2. 2282
    “…The diastolic function of LV was evaluated, and its grading was defined from mild (grade1) to severe (grade 3). RESULTS: Results showed that patients with DD had significantly higher age and lower levels of education (P < 0.001 and P = 0.005, respectively). …”
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    The effect of physical activity level on the severity of diastolic dysfunction
  3. 2283
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    Severe form of lymphocutaneous sporotrichosis: a case report
  4. 2284
    “…Thrombocytopenia is the most common hemostatic change in pregnancy, but severe thrombocytopenia is rare. One of the causes, immune thrombocytopenic purpura (ITP), is characterized by increased platelet destruction by immunoglobulin G (IgG) antibodies, presenting a high risk of hemorrhage for the patient, but also for the fetus, since antibodies may cross the placenta. …”
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    Refractory Severe Thrombocytopenia during Pregnancy: How to Manage
  5. 2285
    “…CONCLUSIONS: Neuroradiological indices of the brain atrophy do not provide an unequivocal distinction in patients with severe AS. Most observations imply that brain atrophy in patients with severe AS is primarily a consequence of physiological ageing of the brain.…”
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    Excessive brain atrophy in patients with severe aortic stenosis
  6. 2286
    “…Major complications included aspiration pneumonia (n = 1), severe gastroesophageal reflux (n = 1), and central nervous signs (=1). …”
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    Challenges of transsphenoidal pituitary surgery in severe brachycephalic dogs
  7. 2287
    “…Electrolyte imbalances are common problems among hospitalized patients, and they can have severe consequences. Although rare, severe hyponatremia or low sodium (Na) levels have been associated with the occurrence of rhabdomyolysis. …”
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    Rhabdomyolysis in the Setting of Severe Hyponatremia: A Case Report
  8. 2288
    “…Such cases present as severe scrub typhus, and their treatment remains a challenging problem. …”
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    Antibiotic Combination Therapy for Severe Scrub Typhus: Is It Necessary?
  9. 2289
    “…The patient was diagnosed with severe ARDS caused by OJT, which had been prescribed 4 weeks prior to admission. …”
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    Severe acute respiratory distress syndrome caused by Otsujito
  10. 2290
    “…Severe hypoxaemia, characteristic of COPD with severe pulmonary hypertension, is due to a combination of greater ventilation–perfusion mismatch, increased intrapulmonary shunt and reduced P(vO(2)), with negligible hypoxic pulmonary vasoconstriction regulation https://bit.ly/3Wnzpik…”
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    Mechanisms of hypoxaemia in severe pulmonary hypertension associated with COPD
  11. 2291
    “…CONCLUSIONS: Although human metabolism of ropinirole is mainly mediated through CYP1A2, the current study shows that several canine CYP isoforms are able to contribute to the clearance of ropinirole in dogs. …”
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    Metabolism of ropinirole is mediated by several canine CYP enzymes
  12. 2292
    por Kim, Sang-Heon
    Publicado 2023
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    Roles of Tissue Inhibitor of Metalloproteinase-1 in Severe Asthma
  13. 2293
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    Alopecia secondary to severe discoid lupus responding to anifrolumab
  14. 2294
    “…The excellent results for monoclonal antibodies in the treatment of severe uncontrolled asthma (SUCA) represent a milestone in current treatment of asthmatic disorders. …”
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    Efficacy and Potential Positioning of Tezepelumab in the Treatment of Severe Asthma
  15. 2295
    “…Positive fecal occult blood supported the diagnosis, and his formula was changed to an extensively hydrolyzed formula (eHF). This is a case of severe CMPA with prolonged vomiting and FTT presenting with severe metabolic acidosis with an elevated anion gap. …”
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    The Cause of Severe Metabolic Acidosis With Vomiting in a Neonate
  16. 2296
    “…Conclusion  Our results show that severe COVID-19 is associated with increased levels of α (E) fibrinogen and decreased relative levels of γˊ fibrinogen, which may be a cause or consequence of severe disease, but this is not associated with the development of thrombosis.…”
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    Levels of Fibrinogen Variants Are Altered in Severe COVID-19
  17. 2297
    “…Chest and abdominal computed tomography showed interstitial pneumonia, severe pancreatitis, and a right adrenal tumor. The patient also developed vertebral artery dissection and medullary infarction. …”
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    Pheochromocytoma Multisystem Crisis Complicated by Severe Acute Pancreatitis
  18. 2298
    “…Inherited and acquired coagulopathy are frequently associated with major bleeding in severe trauma, cardiac surgery with cardiopulmonary bypass, and postpartum hemorrhage. …”
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    Perioperative Considerations in Management of the Severely Bleeding Coagulopathic Patient
  19. 2299
    “…This case accentuates the importance of vigilance in observing patients with severe COVID-19 pneumonia for potential opportunistic infections, particularly given the inherent risks associated with prolonged corticosteroid therapy. …”
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    Concomitant Pulmonary Aspergillosis Following Severe COVID-19
  20. 2300
    “…This study aimed to evaluate risk factors for mortality and prognosis of adult moderate/severe COVID-19 patients treated with remdesivir, and safety and tolerability of 5 days of remdesivir treatment. …”
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    Remdesivir treatment for patients with moderate to severe COVID-19
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