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  1. 2381
    “…The effects of several alcohols on the resting potential, action potential, and voltage-clamp currents of the squid giant axon have been measured. …”
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    The Effects of Several Alcohols on the Properties of the Squid Giant Axon
  2. 2382
    por Laterre, Pierre-François
    Publicado 2007
    “…Drotecogin alfa (activated; DrotAA) was approved in 2001 by the US Food and Drug Administration for the treatment of patients with severe sepsis who are at high risk for death. The European Agency for the Evaluation of Medical Products also recommended that DrotAA could be administered to patients with severe sepsis and multiple organ dysfunction when added to the best standard care. …”
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    Clinical trials in severe sepsis with drotrecogin alfa (activated)
  3. 2383
    “…Angiographically, the patient exhibited severe atherosclerotic changes of the supraaortic large vessels. …”
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    Severe supraaortal atherosclerotic disease resembling Takayasu’s Arteritis
  4. 2384
    “…To investigate the relationship between the FTO gene and obesity in the Japanese, we genotyped single nucleotide polymorphisms (SNPs) in the FTO genes from severely obese subjects [n = 927, body mass index (BMI) ≥ 30 kg/m(2)] and normal-weight control subjects (n = 1,527, BMI < 25 kg/m(2)). …”
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    Variations in the FTO gene are associated with severe obesity in the Japanese
  5. 2385
    “…We assessed the short and long term outcome of severe anaemia in Malawian children and identified potential risk factors for death and further severe anaemia. …”
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    Long Term Outcome of Severe Anaemia in Malawian Children
  6. 2386
    por Go, Tohshin, Konishi, Yukuo
    Publicado 2008
    “…CONCLUSIONS: Oral imitation reappears in a similar way to primitive reflexes in patients showing severely impaired cortical function and little voluntary movement of their extremities due to severe brain damage, suggesting that neonatal oral imitation is mainly controlled by the subcortical brain region.…”
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    Neonatal Oral Imitation in Patients with Severe Brain Damage
  7. 2387
    “…RESULTS: The number of patients with hypoglycaemia and hyperglycaemia was highly dependent on the severity of sepsis (critical hypoglycaemia ≤ 40 mg/dl: sepsis: 2.1%, severe sepsis: 6.0%, septic shock: 11.5%, p = 0.1497; hyperglycaemia: >140 mg/dl: sepsis: 76.6%, severe sepsis: 88.0%, septic shock: 100%, p = 0.0006; >179 mg/dl: sepsis: 55.3%, severe sepsis: 73.5%, septic shock: 88.5%, p = 0.0005; >240 mg/dl: sepsis: 17.0%, severe sepsis: 48.2%, septic shock: 45.9%, p = 0.0011). …”
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    The impact of the severity of sepsis on the risk of hypoglycaemia and glycaemic variability
  8. 2388
    “…We carried out a comprehensive study to identify factors influencing both mortality and morbidity for children less than 5 years of age hospitalized with severe pneumonia. METHODS: 200 hospitalized children aged 2–60 months with World Health Organization (WHO) defined severe pneumonia were enrolled in the study. …”
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    Factors determining the outcome of children hospitalized with severe pneumonia
  9. 2389
    “…In this article, we review the evidence for the use of memantine in patients with AD, ranging from the mild to severe stages of disease.…”
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    Memantine: efficacy and safety in mild-to-severe Alzheimer’s disease
  10. 2390
    “…Changes in local transmission dynamics and genetic changes in DENV-3 are likely increasing emergence of severe dengue epidemics in Sri Lanka.…”
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    Severe Dengue Epidemics in Sri Lanka, 2003–2006
  11. 2391
    “…OBJECTIVE: The objective of this study was to determine if the white blood cell count can predict severity of injury in blunt trauma victims. METHODS: This was a retrospective study comparing two groups of blunt trauma victims by severity of injury, one with significant injury and one without significant injury, and comparing their initial WBC in the emergency department (ED). …”
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    Leukocytosis as a Predictor of Severe Injury in Blunt Trauma
  12. 2392
    “…We report a 68-year-old patient with severe global aphasia secondary to a large left hemisphere infarction including the parietal lobe. …”
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    Dissociation of Exact and Approximate Calculation in Severe Global Aphasia
  13. 2393
    “…Human movements show several prominent features; movement duration is nearly independent of movement size (the isochrony principle), instantaneous speed depends on movement curvature (captured by the 2/3 power law), and complex movements are composed of simpler elements (movement compositionality). …”
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    Movement Timing and Invariance Arise from Several Geometries
  14. 2394
    “…The pathogenesis of sepsis is complex and comprises a mosaic of interconnected pathways. Several attempts to improve patient outcomes by targeting specific components of this network have been unsuccessful. …”
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    Clinical review: Extracorporeal blood purification in severe sepsis
  15. 2395
    “…INTRODUCTION: To establish a prognostic model for predicting 14-day mortality in ICU patients with severe sepsis overall and according to place of infection acquisition and to sepsis episode number. …”
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    Model for predicting short-term mortality of severe sepsis
  16. 2396
    por Chalmers, James D
    Publicado 2009
    “…The past 15 years have seen major advances in our understanding of severity assessment in community-acquired pneumonia (CAP). …”
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    ICU admission and severity assessment in community-acquired pneumonia
  17. 2397
    por Vena, Gino A, Cassano, Nicoletta
    Publicado 2007
    “…The effectiveness of adalimumab in psoriasis was previously suggested by the subset analysis of patients enrolled in PsA trials who were affected by concomitant psoriasis, and recently confirmed by a phase II trial and the preliminary results from phase III trials in moderate to severe psoriasis. These results demonstrate that adalimumab is effective in improving psoriasis and quality of life, with sustained effects over ≥ 1-year treatment period. …”
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    Drug focus: adalimumab in the treatment of moderate to severe psoriasis
  18. 2398
    “…In the present study, we have analyzed the levels of various complement components in blood samples from dengue fever (DF) and dengue hemorrhagic fever (DHF) patients and found that the level of complement activation is associated with disease severity. METHODS AND RESULTS: Patients with DHF had lower levels of complement factor 3 (C3; p = 0.002) and increased levels of C3a, C4a and C5a (p<0.0001) when compared to those with the less severe form, DF. …”
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    Alternative Complement Pathway Deregulation Is Correlated with Dengue Severity
  19. 2399
    “…The aim of this study was to identify genes involved in emphysema severity in COPD patients. Gene expression profiling was performed on total RNA extracted from non-tumor lung tissue from 30 smokers with emphysema. …”
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    Expression profiling identifies genes involved in emphysema severity
  20. 2400
    “…BACKGROUND: Our study aimed to assess the nationwide trends in the incidence of severe gallstone disease in Taiwan among adults aged ≥20. …”
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    Nationwide epidemiological study of severe gallstone disease in Taiwan
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