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  1. 2461
    por Annane, Djillali
    Publicado 2011
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    Corticosteroids for severe sepsis: an evidence-based guide for physicians
  2. 2462
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    Severe community-acquired pneumonia in the intensive care unit
  3. 2463
    por Trzeciak, Stephen, Rivers, Emanuel P
    Publicado 2005
    “…Microcirculatory dysfunction plays a pivotal role in the development of the clinical manifestations of severe sepsis. Prior to the advent of new imaging technologies, clinicians had been limited in their ability to assess the microcirculation at the bedside. …”
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    Clinical manifestations of disordered microcirculatory perfusion in severe sepsis
  4. 2464
    por Bateman, Ryon M, Walley, Keith R
    Publicado 2005
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    Microvascular resuscitation as a therapeutic goal in severe sepsis
  5. 2465
    “…The aim of this study was to examine efficacy of IMOD in the management of patients with severe sepsis. METHODS: Twenty patients with severe sepsis and acute physiology and chronic health evaluation (APACHE) score of more than 20 were randomized to receive standard treatment of severe sepsis (control group) or standard treatment plus IMOD (IMOD group). …”
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    Examination of Setarud (IMOD™) in the management of patients with severe sepsis
  6. 2466
    “…We aim to describe the health care decision-making process during severe acute obstetric complications among women and their families in rural Bangladesh. …”
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    Accounts of severe acute obstetric complications in Rural Bangladesh
  7. 2467
    “…This review will trace the use of this monoclonal antibody from lymphoid malignancy, to classic autoimmune disease, and specifically severe autoimmune skin diseases. The history leading to different dosing schema with associated pharmacokinetic data will be discussed. …”
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    Rituximab in severe skin diseases: target, disease, and dose
  8. 2468
    “…We review our baboon models of Escherichia coli sepsis that mimic, respectively, the shock/disseminated intravascular coagulation (DIC) and organ failure variants of severe sepsis, and analyse the pathophysiologic processes that are unique to each. …”
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    Pathophysiology, staging and therapy of severe sepsis in baboon models
  9. 2469
    por Falkai, P., Möller, H.-J.
    Publicado 2011
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    Emotional status: diagnosis and treatment for severe psychiatric disorders
  10. 2470
    por Lahan, Vivekananda, Gupta, Ravi
    Publicado 2011
    “…AIMS AND OBJECTIVES: Translation of the Insomnia Severity Index from English to Hindi and Validation of the Hindi version. …”
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    Translation and Validation of the Insomnia Severity Index in Hindi Language
  11. 2471
    “…The hamster model of severe destructive Lyme arthritis facilitates easy assessment of Lyme borreliosis vaccine preparations for deleterious effects while murine models of severe destructive Lyme arthritis allow for investigation of mechanisms of immunopathology.…”
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    Hamster and Murine Models of Severe Destructive Lyme Arthritis
  12. 2472
    por Gerasimov, Lev, Moroz, Viktor
    Publicado 2007
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    Fibrinolysis in early recognition of sepsis in patients with severe trauma
  13. 2473
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    Severity stratification of septic shock according to noradrenaline requirement
  14. 2474
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    Steroid hormone synthesis is impaired in patients with severe sepsis
  15. 2475
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    Hyperhomocysteinaemia as an indicator of infection and disease severity in ICU patients
  16. 2476
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    Interleukin-18 levels reflect the severity of acute pancreatitis
  17. 2477
    por Lapauw, S, Wilmer, A, Bobbaers, H
    Publicado 2003
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    Incidence of organ failure in patients with severe acute pancreatitis
  18. 2478
    “…This study was carried out to identify the factors influencing the severity of acute viral hepatitis A. METHODS: We retrospectively reviewed the medical records of 713 patients with acute hepatitis A, who were divided into two groups: severe hepatitis A (N=87) and non-severe hepatitis A (N=626). …”
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    Factors influencing the severity of acute viral hepatitis A
  19. 2479
    “…Interestingly, our microarray data show that increased expression of inflammatory genes was associated with major clinical features within the MFS patients group; namely severity of the aortic root dilatation (HLA-DRB1 and HLA-DRB5 genes; r = 0.56 for both; False Discovery Rate(FDR) = 0%), ocular lens dislocation (RAET1L, CCL19 and HLA-DQB2; Fold Change (FC) = 1.8; 1.4; 1.5, FDR = 0%) and specific skeletal features (HLA-DRB1, HLA-DRB5, GZMK; FC = 8.8, 7.1, 1.3; FDR = 0%). …”
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    Inflammation Aggravates Disease Severity in Marfan Syndrome Patients
  20. 2480
    “…BACKGROUND: The mortality of severe malaria [cerebral malaria (CM), severe malaria anemia (SMA), acute lung injury (ALI) and acute respiratory distress syndrome (ARDS)] remains high despite the availability associated with adequate treatments. …”
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    Heme Mediated STAT3 Activation in Severe Malaria
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