“…The purpose of this study was to investigate the acute effect of enteric-coated sodium bicarbonate supplementation on the anaerobic performance, physiological profile, and symptoms of gastrointestinal discomfort after severe-intensity intermittent exercise. At the same time, targeted metabolomics was used to study the changes in urine metabolism after ingestion of enteric-coated sodium bicarbonate and to explore the characteristics of biological metabolism. …”
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“…This seems to mean that for patients with severe or even unbearable pain, the benefits of surgery as soon as possible will be significant. …”
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“…La pelvi-périnéologie et les chirurgies bénignes furent sévèrement impactées, la cancérologie restant relativement préservée, en accord avec les recommandations. …”
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“…A significant improvement in HCP self-reported performance was observed in a combined analysis of both activities (mean score, SD 2.65, 1.32 vs 3.15, 1.26; P=.03), with the proportion of learners selecting the answer representing the best clinical option for all 4 questions increasing from 32% (11/34) to 59% (20/34) after the activity. Several unmet educational needs were self-reported or identified from the analysis of incorrectly answered questions, including setting individualized glycemic targets and the potential benefits of sodium-glucose cotransporter 2 inhibitor therapies. …”
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“…Fruit ripening is regulated by several hormone-related genes and transcription factors. …”
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“…The fertility rate stands at 1.3 in several European Union countries. Some people are not having their desired family size or are childless by circumstance. …”
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“…PRISm had higher odds and more severity in spirometry-defined SAD (pre-bronchodilator: odds ratio [OR]: 5.99, 95% confidence interval [95%CI]: 3.87–9.27, P < 0.001; post-bronchodilator: OR: 14.05, 95%CI: 8.88–22.24, P < 0.001), IOS-defined SAD (OR: 2.89, 95%CI: 1.82–4.58, P < 0.001), and CT-air trapping (OR: 2.01, 95%CI: 1.08–3.72, P = 0.027) compared with healthy control after adjustment for confounding factors. …”
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“…Subgroup analysis demonstrated that patients with PerCI were in a more serious health condition at admission since those patients had worse nutritional status, more electrolyte imbalance and infection-related comorbidities, and more severe illness scores. Eight variables, including albumin, serum calcium, red cell volume distributing width (RDW), blood pH, heart rate, respiratory failure, pneumonia, and the Sepsis-related Organ Failure Assessment (SOFA) score, were significantly associated with PerCI, according to the least absolute shrinkage and selection operator (LASSO) logistic regression model combined with the 10-fold cross-validation. …”
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“…Mouse models can serve as an important tool for the investigation of biomarkers in glioblastoma, but several glioblastoma models indicated only low TSPO-PET signals in contrast to high TSPO-PET signals of human glioblastoma. …”
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“…The protective effects of rEsAMA1 and rEsIMP1 against E. stiedae infection were assessed using several indicators. Sera were collected weekly to detect the specific antibody levels. …”
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“…Safety will be assessed by frequency and severity of adverse events. Current Status: EMANATE is currently underway and began enrolling patients in early 2022. …”
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“…We report a rare case of severe hypercalcemia caused by systemic granulomatous disease after intravesical Bacillus Calmette-Guerin (BCG) treatment for bladder cancer (BCGosis). …”
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“…CONCLUSIONS: In our study, sex differences were observed in the relationship of older versus younger age to several measures of body composition, suggesting greater relative fat mass with aging, particularly in men. …”
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“…Four months prior to current hospitalization, he developed avascular necrosis of the hip and became essentially bedbound from severe hip pain. Since immobilization, his calcium was noted to increase, with the highest corrected calcium of 10.9 mg/dL (8.5-10.5 mg/mL), necessitating tapering and eventual discontinuation of calcium supplements and calcitriol. …”
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“…INTRODUCTION: Hyperosmolar crisis, which includes diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS), is a severe and acute complication of diabetes. The estimated mortality rates of DKA and HHS are 6.8% and 10%, respectively (Benoit, Zhang, Geiss, Gregg, & Albright, 2018) (Pasquel & Umpierrez, 2014). …”
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“…INTRODUCTION: Vitamin D deficiency is a very common condition, which has been associated with more severe presentations of PHPT. It has been suggested that the Vitamin D replacement improves this prognosis, but there are few data regarding its effect on mineral homeostasis. …”
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“…Additionally, we analyzed mRNA levels of several genes of interest, including WNT7b, WNT11, TCF7, SFRP4, FZD5, PP2R2A, and DVL3 mRNA. …”
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“…RESULTS: Overall, DCCR was well tolerated with the majority of adverse events (AEs), (77.6%) having grade 1 or 2 severity. Treatment-emergent adverse events (TEAEs) occurred in 98.4% of participants. …”
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“…Similarly, patients with weight gain had significantly higher preoperative serum calcium (p=0.044), alkaline phosphatase (ALP) (p=0.001), and parathyroid hormone levels (p=0.001), indicating biochemically severe disease On binomial logistic regression analysis, preoperative body weight (β= -0.045, p=0.04), symptomatic presentation (β=0.217, p=0.02), and ALP (β=0.003, p=0.04) emerged as significant predictors of postoperative weight gain. …”
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“…INTRODUCTION: During the coronavirus disease (COVID-19) pandemic a state of emergency was declared where people were instructed to stay at home to prevent disease transmission, which exerted severe disruptions in the routine care of patients. …”
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