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Mostrando 832,201 - 832,220 Resultados de 834,362 Para Buscar '"Severance"', tiempo de consulta: 4.09s Limitar resultados
  1. 832201
    “…Variants in SH2B1 or a 220–kilobase pair distal deletion of chromosome 16p11.2, including SH2B1, are associated with hyperphagia (pathologic insatiable hunger), severe early-onset obesity, reduced final height, and insulin resistance. …”
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    RF24 | PSUN91 Body Mass Index and Weight Reduction in Patients With SH2B1 Genetic Variant Obesity After One Year of Setmelanotide
  2. 832202
    “…We also note that the severity of alpelisib side effects appeared to be dose-dependent, as seen in the clinical trial. …”
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    ODP173 Control of Alpelisib-Induced Hyperglycemia With DPP4- Inhibitors as add on to Metformin and Insulin
  3. 832203
    “…We have previously reported that patients with familial partial lipodystrophy (FPLD) present with metabolic severity equivalent to what is observed at 8-12 BMI points higher in a population with common obesity. …”
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    RF24 | PSUN126 A Very-Low Calorie Diet Can Reduce Insulin Resistance and Cause Remission of Diabetes Mellitus and Hypertriglyceridemia in a Patient With Familial Partial Lipodystrophy Type 2
  4. 832204
    “…No serious adverse event (AE) was reported and all AEs were mild or moderate in severity. The most commonly-reported AEs included diarrhea, nausea, vomiting and decreased appetite (each reported in six participants [37.5%] receiving IBI362). …”
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    ODP014 Safety and Efficacy of IBI362 (LY3305677) 9 mg and 10 mg in Chinese Adults with Overweight or Obesity
  5. 832205
    “… : The severity of liver fibrosis in patients with NAFLD is a strong predictor of cardiovascular mortality, independently of other well-known cardiovascular risk factors. …”
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    OR02-1 Differences in HDL Particle Composition in Patients with Nonalcoholic Fatty Liver Disease (NAFLD) and Advanced Liver Fibrosis May Explain Higher Cardiovascular Risk
  6. 832206
    “…METHODS: Study 303 was a 12mo randomized, double-blind, PBO-controlled (first 6mo [Period 1]), phase 3 study in participants ≥18y with insomnia disorder and baseline Insomnia Severity Index total score ≥15. Patients with diabetes Type 1 or Type 2, identified by concomitant medications, were allowed to participate as long as their condition was considered stable and likely to be so during the year of treatment. …”
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    PSUN201 Efficacy and Safety of Lemborexant in Diabetic Patients With Insomnia Disorder
  7. 832207
    “…BACKGROUND: Metabolic and bariatric surgery (MBS) is currently the most effective weight loss treatment in adults and children with severe obesity. However, up to 50% of adolescents continue to have obesity three years post-MBS. …”
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    LBODP002 Phase II Open-label Pilot Trial Of Liraglutide In Adolescents With Obesity After Vertical Sleeve Gastrectomy: Interim Results From 8-weeks Of Treatment
  8. 832208
    “…Hirsutism (females; rated on a semi-quantitative scale: 0=absent; 1=mild; 2=moderate; 3=severe), blood pressure, edema and serum potassium were assessed at regular intervals. …”
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    PMON163 Effect of Osilodrostat on Androgens and Adrenal Hormones in Patients With Cushing's Disease: Long-Term Findings From the Phase III, Prospective LINC 3 Study
  9. 832209
    “…Because NMB is also expressed in several cancer cells and stimulates ACTH secretion, we hypothesized that NMB is related to corticotroph adenoma cell proliferation and hormone secretion. …”
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    ODP338 Neuromedin B Receptor Antagonist Suppresses ACTH Secretion and Cell Proliferation in Human and Mouse Corticotroph Adenoma
  10. 832210
    “…OB presented with more severe acanthosis (p<0.0001) and higher HbA1c (OB 5.5±0.5, NO 5.2±0.3; %, p<0.0001), ALT (OB 35±30, NO 22±17; IU/L, p=0.0006), and triglycerides (OB 145±90, NO 110,±88; mg/dL, p=0.002). …”
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    OR15-4 Heterogeneity of Clinical Presentation of Adolescent PCOS Is Attributable to Distinct Subtypes
  11. 832211
    “…Following the first hospitalization, she developed severe orthostatic hypotension, chest pain, shortness of breath, fatigue, anxiety, memory, concentration and word finding difficulty. …”
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    ODP291 A Series of COVID Reinfections in a Vaccinated Patient leading to Development of Neurogenic Orthostatic Hypotension and Postural Orthostatic Tachycardia
  12. 832212
    “…Most AEs were mild or moderate and unlikely related to GH treatment. One severe AE (surgery for elbow fracture) occurred in the somapacitan/somapacitan group. …”
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    RF26 | PMON334 Once-Weekly Somapacitan in Growth Hormone Deficiency: 4-Year Efficacy and Safety Results from REAL 3, a Randomised Controlled Phase 2 Trial
  13. 832213
    “…BACKGROUND: Radioiodine (RAI) therapy is an important adjuvant therapy for differentiated thyroid carcinoma (DTC) patients. Several studies have demonstrated the efficacy of RAI in reducing the risk of thyroid cancer recurrence and mortality; however, the ideal timing to initiate RAI after surgery is debatable. …”
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    PSAT243 Late Versus Early Administration of Radioiodine Therapy for Patients with Differentiated Thyroid Cancer: A Systematic Review and Meta-analysis
  14. 832214
    “…Per design, markers of androgen excess including total testosterone (p<0.001), free testosterone (p<0.001), degree of hirsutism (p=0.004), and severity of acne (p<0.001) were worse in girls with PCOS. …”
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    ODP424 Postprandial Adipose Insulin Resistance in Adolescent Girls with PCOS and Obesity
  15. 832215
    “…Fasting insulin was not statistically different between PL and NAFLD (median 26.4 [interquartile range 21.3,51.2]) vs 31.6 mcU/L [15.1-33.4], P=0.052); however, IR was more severe in PL vs NAFLD based on both HOMA-IR (15.5±16.2 vs 7.6±5.2, P=0.003) and LP-IR (65.1±19.3 vs 58.5±16.7, P=0.03). …”
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    RF04 | PSUN333 Divergent Pathways in Liver Triglyceride Storage and Secretion in Partial Lipodystrophy vs. Obesity Associated NAFLD
  16. 832216
    “…The absence of reports from low-income countries may be due to several reasons, such as barriers to molecular diagnosis, scientific access, and specialized medical assistance. …”
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    RF02 | PMON189 Temporal and Social trends towards sex assignment and gender change in the 5α-reductase type 2 deficiency
  17. 832217
    “…Children and adults with ACH have disproportionate short stature and are at risk for several significant co-morbidities, including obstructive sleep apnea, chronic otitis media with conductive hearing loss, and spinal stenosis. …”
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    PSAT105 Evaluation of Body Mass Index and Metabolic Parameters in Children with Achondroplasia Participating in the PROPEL Study
  18. 832218
    “…There were no Serious or severe Adverse Events, nor changes in laboratory values of concern. …”
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    PMON69 Effective Suppression of Gonadotropins and Gonadal Steroids Following Oral Administration of Leuprolide
  19. 832219
    “…Surgery effectively reduces tumor size but is rarely curative and frequently complicated by hypopituitarism of variable severity and local complications. Presentation: Monday, June 13, 2022 12:30 p.m. - 2:30 p.m.…”
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    LBMON173 Non-functioning Seller Masses: Tumor Types, Surgical Management And Course Over Time
  20. 832220
    “…CLINICAL CASE: 59F with classic Cushing's stigmata (including striae, plethora, supraclavicular and dorsocervical fat pads, muscle wasting), and two-year history of rapid weight gain, hypertension, T2DM, hyperlipidemia, severe osteoporosis complicated by multiple vertebral compression fractures, presented for workup and management of ACTH dependent CS. …”
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    PMON123 Diagnostically Challenging Case of Cushing's Syndrome from a Pancreatic Neuroendocrine Tumor Treated with Radiofrequency Ablation
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