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  1. 832301
    “…A total of 24 patients reported 37 adverse events (AEs) during the study, most common being pain, pyrexia and swelling but none of the AEs reported during the study were considered as severe in intensity. There were no safety concerns reported. …”
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    An Open-Labeled Randomized Prospective Multi-center Study to Evaluate the Efficacy and Safety of Intra-articular Injection of OSSINEXT™, an Autologous Growth Factor Concentrate (AGFC) Compared to Hyaluronic Acid (HA) in Knee Osteoarthritis
  2. 832302
    “…BACKGROUND: Severe postoperative pain not only is a considerable burden for patients but also leads to overprescription of opioids, resulting in considerable health concerns. …”
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    A digital application and augmented physician rounds reduce postoperative pain and opioid consumption after primary total knee replacement (TKR): a randomized clinical trial
  3. 832303
    “…Additionally, acupuncture had no observable severe adverse influences on the newborns. More large-scale and well-designed RCTs are still needed to further confirm these results. …”
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    Acupuncture for low back and/or pelvic pain during pregnancy: a systematic review and meta-analysis of randomised controlled trials
  4. 832304
    “…Studies were eligible when they reported the number of documented, symptomatic, severe covid-19 infections, covid-19 related hospital admissions, or covid-19 related deaths among populations that were vaccinated and unvaccinated. …”
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    Effectiveness of heterologous and homologous covid-19 vaccine regimens: living systematic review with network meta-analysis
  5. 832305
    “…BACKGROUND: Mechanical ventilation can lead to the severe impairment of the metabolic pathway of alveolar surfactants, inactivating alveolar surfactants and significantly reducing lung-chest compliance. …”
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    Different positive end expiratory pressure and tidal volume controls on lung protection and inflammatory factors during surgical anesthesia
  6. 832306
    “…Thus, a novel pretreatment method was developed, denoted effervescent reaction-assisted dispersive solid-phase microextraction (ER-DSM), which was combined with high performance liquid chromatography-fluorescence detection (HPLC-FLD) to rapidly quantify trace-level BPs in several drinks. The morphology and structure of the CoNi@NGC adsorbent were characterized in detail using scanning electron microscopy (SEM), transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FT-IR), N(2) adsorption and desorption (BET-BJH), X-ray photoelectron spectroscopy (XPS), and vibrating sample magnetometry (VSM). …”
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    磁性三维氮掺杂碳纳米材料对6种双酚类化合物的吸附性能及其在泡腾分散微萃取中的应用
  7. 832307
    “…CONCLUSIONS: The intervention improved several dietary outcomes but had modest impacts on PA and HRQOL, underscoring the challenge of behavior change during pregnancy. …”
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    Effects of a behavioral intervention on physical activity, diet, and health-related quality of life in pregnant women with elevated weight: results of the HIPP randomized controlled trial
  8. 832308
    “…BACKGROUND: Ageing is accompanied by changes in sleep, while poor sleep is suggested as a risk factor for several health outcomes. Non-pharmacological approaches have been proposed to improve sleep in elderly; their impact remains to be investigated. …”
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    Association of physical activity, sedentary behaviour, and daylight exposure with sleep in an ageing population: findings from the Whitehall accelerometer sub-study
  9. 832309
    “…HP eradication among subjects with several comorbidities mandates eradication protocol intensification to avoid treatment failure.…”
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    Effect of Helicobacter pylori eradication on metabolic profile: an international, multicenter, case-control study
  10. 832310
    “…RESULTS: We discovered that several members of the nuclear import receptor protein family can reduce the formation of pathological TDP-43 aggregates. …”
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    Nuclear import receptors are recruited by FG-nucleoporins to rescue hallmarks of TDP-43 proteinopathy
  11. 832311
    “…Despite growing knowledge about transmission and relatively wide access to prophylaxis, the world is still facing a severe acute respiratory syndrome coronavirus 2 (SARS CoV 2) global pandemic. …”
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    The utility of telemedicine in managing patients after COVID-19
  12. 832312
    “…A mixed study design (meta-analysis and mapping review) was chosen. We gathered several large Canadian, US and Brazilian data sets of MALDI-TOF results for organisms cultured from quarter milk samples. …”
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    Diagnosing Intramammary Infection: Meta-Analysis and Mapping Review on Frequency and Udder Health Relevance of Microorganism Species Isolated from Bovine Milk Samples
  13. 832313
    “…METHODS: Here, we performed MR and colocalization analysis using multi-tissue (cerebrospinal fluid (CSF), plasma, and brain from pre- and post-meta-analysis of several disease-focus cohorts including Alzheimer disease (AD)) protein quantitative trait loci (pQTLs) as instrumental variables to infer protein effects on 211 phenotypes, covering seven broad categories: biological traits, blood traits, cancer types, neurological diseases, other diseases, personality traits, and other risk factors. …”
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    Mendelian randomization and genetic colocalization infer the effects of the multi-tissue proteome on 211 complex disease-related phenotypes
  14. 832314
    “…The most common adverse events in children receiving ELX/TEZ/IVA were headache and cough (30.0% and 23.3%, respectively); most adverse events were mild or moderate in severity. CONCLUSIONS: In this first randomized, controlled study of a cystic fibrosis transmembrane conductance regulator modulator conducted in children 6 through 11 years of age with F/MF genotypes, ELX/TEZ/IVA treatment led to significant improvements in lung function, as well as robust improvements in respiratory symptoms and cystic fibrosis transmembrane conductance regulator function. …”
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    Efficacy and Safety of Elexacaftor/Tezacaftor/Ivacaftor in Children 6 Through 11 Years of Age with Cystic Fibrosis Heterozygous for F508del and a Minimal Function Mutation: A Phase 3b, Randomized, Placebo-controlled Study
  15. 832315
    “…Néanmoins, les complications peuvent être sévères et le diagnostic sémiologique précoce est nécessaire pour adapter rapidement la prise en charge.…”
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    Maladie de Kawasaki de l’adulte satellite d’une infection à SARS-CoV-2
  16. 832316
    por Piroth, M., Bourrat, E., Barbarot, S.
    Publicado 2022
    “…DISCUSSION: Le PIMS est une maladie rare et sévère, encore mal comprise, décrite au cours de la pandémie COVID-19. …”
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    L’érythème en lunettes, un signe commun au syndrome inflammatoire multisystémique pédiatrique (PIMS) et à la maladie de Kawasaki
  17. 832317
    “…CONCLUSION: The present study provides an in-depth insight into the molecular regulatory mechanisms behind M. bovis infection through biological investigation of the candidate non-preserved modules directly related to bTB development. Furthermore, several hub-central genes/TFs were identified that were significant in determining the fate of M. bovis infection and could be promising targets for developing novel anti-bTB therapies and diagnosis strategies.…”
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    In-depth systems biological evaluation of bovine alveolar macrophages suggests novel insights into molecular mechanisms underlying Mycobacterium bovis infection
  18. 832318
    “…BACKGROUND: Coinfections, both bacterial and viral, occur with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, but prevalence, risk factors, and associated clinical outcomes are not fully understood. …”
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    303. Viral and bacterial infections among adults hospitalized with COVID-19, Coronavirus Disease 2019-Associated Hospitalization Surveillance Network, 14 states, March 2020–February 2022
  19. 832319
    “…This study evaluated nirmatrelvir/r in nonhospitalized, symptomatic adults with COVID-19 at high risk of progressing to severe disease. We report secondary efficacy endpoints associated with COVID-19─related medical visits, including hospitalization details and oxygen support, as of the primary completion data cutoff (Dec 11, 2021). …”
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    786. Effect of Nirmatrelvir/Ritonavir versus Placebo on COVID-19─Related Hospitalizations and Other Medical Visits
  20. 832320
    “…Subjects with RSV isolates harboring F protein sequence variations that maintained susceptibility to nirsevimab neutralization were balanced between treatment groups with no association with RSV disease severity. No subjects with non-protocol defined MA RSV LRTI cases or hospitalization due to any RSV respiratory illness had an RSV isolate conferring nirsevimab resistance. …”
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    94. Pooled analysis of nirsevimab resistance through 150 days post dose in preterm and term infants
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