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  1. 832341
    “…RESULTS: Eight cases with 17p13.3 CNVs consisted of five fetuses, one aborted embryo and two probands manifested severe congenital defects. The indications of prenatal testing varied considerably for the five fetuses, including ultrasound abnormalities (n = 3), segmental deletions indicated by non-invasive prenatal testing (n = 1), and intellectual disability in the mother of one fetus (n = 1). …”
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    Clinical findings and genetic analysis of patients with copy number variants involving 17p13.3 using a single nucleotide polymorphism array: a single-center experience
  2. 832342
    “…The PDC was effective in blocking the onset or the progression of disease in several mouse models of autoimmunity (type 1 diabetes, systemic lupus erythematosus, and multiple sclerosis) and a mouse model of allergic asthma in the absence of detectable toxicity. …”
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    How GRAIL controls Treg function to maintain self-tolerance
  3. 832343
    “…These findings suggest that several hip muscles can be moderately or largely affected after arthroscopy (abductors) or surgical hip dislocation (internal and external rotators, abductors and quadriceps). …”
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    Evolution of Hip Muscles Strength in Femoroacetabular Impingement Patients Treated by Arthroscopy or Surgical Hip Dislocation: A Retrospective Exploratory Study
  4. 832344
    “…INTRODUCTION: Transcatheter Aortic Valve Implantation (TAVI) has been established as the preferential option for patients suffering from symptomatic severe aortic stenosis with high surgical risk. Due to the implantation of prosthesis on younger patients, the durability of TAVI devices becomes a crucial issue, especially beyond 5 years of follow-up [1]. …”
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    Using artificial intelligence for device identification and characterization in angiographic sequences of TAVI procedures as radiomic biomarkers for prosthesis deterioration
  5. 832345
    “…After the standardization of the variables and a feature selection process, several missing value imputation methods and around 12 different Machine Learning algorithms were tested to predict the AF recurrence in a subset of patients who developed AF in the first semester of 2015, in order to select the algorithms with the highest prediction accuracy for further tests. …”
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    Prediction of new onset atrial fibrillation recurrence or persistence with artificial intelligence: first insights of the PRAFAI study
  6. 832346
    “…Patients were classified into three groups: Group A, Patients not able to answer the survey question because of a severe cognitive impairment (n(p) = 8); Group B, Patients able to answer the survey question with low or no cognitive impairment and high motor disability (n(p) = 10); and Group C, Patients able to answer the survey question with low or no cognitive impairment and low motor disability (n(p) = 7). …”
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    Understanding the challenges, unmet needs, and expectations of mucopolysaccharidoses I, II and VI patients and their caregivers in France: a survey study
  7. 832347
    “…INTRODUCTION: Epilepsy is one of the most common neurological disorders. Though there are several effective drugs for treating epilepsy, most drugs are associated with side effects and drug interactions. …”
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    Effect of Hydroalcoholic Extract of Stachys lavandulifolia on Pentylenetetrazole-induced Seizures in Male Mice: The Role of GABAergic and Opioidergic Systems
  8. 832348
    “…OBJECTIVE: This study aimed to provide a basis for epidemic prevention and control measures as well as the management of re-positive personnel by analyzing and summarizing the characteristics of re-positive patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant infections discharged from a hospital in the Ningxia Hui Autonomous Region in 2021. …”
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    A comparative study of virus nucleic acid re-positive and non-re-positive patients infected with SARS-CoV-2 Delta variant strain in the Ningxia Hui Autonomous Region
  9. 832349
    “…BACKGROUND: Severe acute respiratory syndrome coronavirus 2 causes coronavirus disease 19 (COVID-19). …”
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    Bioinformatic analysis and preliminary validation of potential therapeutic targets for COVID-19 infection in asthma patients
  10. 832350
    “…In exposed cells, changes in the expression of genes encoding DNA repair factors (ATM, ARID2, TRP53) were observed, and increased expression of several genes encoding telomeric DNA binding factors (SMG7, TERT, TEN1, UPF1, ZBTB48) were also found. …”
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    Genome-wide distribution of histone trimethylation reveals a global impact of bisphenol A on telomeric binding proteins and histone acetyltransferase factors: a pilot study with human and in vitro data
  11. 832351
    “…CONCLUSION: Serum BAFF levels and LUS B-lines number could be useful supportive biomarkers for detecting and evaluating the severity and/or subsets of CTD-ILD. If corroborated, combining imaging, serological, and sonographic biomarkers might be beneficial and comprehensive in management of CTD-ILD.…”
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    Serum B-cell activating factor and lung ultrasound B-lines in connective tissue disease related interstitial lung disease
  12. 832352
    “…SWE(single-point) may provide additional valuable information for assessing the severity of plantar fasciopathy.…”
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    Elasticity evaluation of the plantar fascia: A shear wave elastography study involving 33 early-stage plantar fasciopathy subjects
  13. 832353
    “…Preterm infants with CS may have more severe features of disease than the term ones, due to the combined pathogenic effect of both CS and prematurity. …”
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    Congenital syphilis in a preterm newborn with gastrointestinal disorders and postnatal growth restriction
  14. 832354
    “…Treatment-related adverse events (TRAEs) were recorded in 48 cases (96.0%). Severe TRAEs occurred in 3 (6.0%) cases, including myelosuppression, drug-induced liver injury and death related to haemoptysis. …”
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    Safety and effectiveness of neoadjuvant PD-1 inhibitor (toripalimab) plus chemotherapy in stage II–III NSCLC (LungMate 002): an open-label, single-arm, phase 2 trial
  15. 832355
    “…CONCLUSIONS: Fecal biomarkers calprotectin and lactoferrin correlate with histological disease activity and differentiate between patients in histological remission from those with evidence of moderate to severe disease activity. Their noninvasiveness, in addition to being inexpensive, supports their use in the clinical monitoring of patients with UC.…”
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    Assessing Histological Inflammatory Activity in Patients With Ulcerative Colitis: A Diagnostic Accuracy Study Testing Fecal Biomarkers Lactoferrin and Calprotectin
  16. 832356
    “…Furthermore, the ferritin level may be one of the predictor of severe hyper-inflammatory syndrome leading to aggressive and urgent treatment with methylprednisolone pulse.…”
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    Methylprednisolone pulses as an initial treatment in hyperinflammatory syndrome after COVID-19 in children: evaluation of laboratory data, serial echocardiography and outcome: a case series
  17. 832357
    “…BACKGROUND: Several kinds of motor dysfunction have been studied for predicting future fall risk in community-dwelling older individuals. …”
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    Association of motor index scores with fall incidence among community-dwelling older people
  18. 832358
    “…(family: Rutaceae) is reported to have several actions on the central nervous system producing beneficial effects in anxiety, Alzheimer's disease, Parkinson's disease, epilepsy, and convulsion. …”
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    Antidepressive-Like Effect of Aegle marmelos Leaf Extract in Chronic Unpredictable Mild Stress-Induced Depression-Like Behaviour in Rats
  19. 832359
    “…CONCLUSIONS: While a slender habitus is commonly known for MFS and LDS patients, our data show that many MFS and LDS patients (especially female) do not fit this phenotypic characteristic and are obese, which is associated with a more severe aortic phenotype. This topic should be included in the clinical assessment of affected MFS and LDS patients, in addition to measurement of the aortic diameters. …”
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    The relation of aortic dimensions and obesity in adults with Marfan or Loeys-Dietz syndrome
  20. 832360
    “…All AEs were of mild-to-moderate severity, and consistent with the known profiles of the compounds. …”
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    Randomized, open-label, phase 2a study to evaluate the contribution of artefenomel to the clinical and parasiticidal activity of artefenomel plus ferroquine in African patients with uncomplicated Plasmodium falciparum malaria
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