“…High physiological concentrations of acute ethanol activated the Jak-Stat and p38 MAPK pathways and inhibited HCV replication in several independent replicon cell lines. Moreover, acute ethanol induced Stat1 serine phosphorylation, which was partially mediated by the p38 MAPK pathway. …”
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“…MR investigations with a high rf-pulse density lasting below a minute can establish volumes of several cubic millimeters with temperature increases high enough to start cell destruction. …”
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“…DISCUSSION: In the circulation of normal individuals is a small population of CD34(-) mononuclear cells that proliferate rapidly in culture as an adherent population with a variable morphology, display cytoskeletal, cytoplasmic, and surface markers of mesenchymal precursors, and differentiate into several lineages (fibroblasts, osteoblasts, and adipocytes). …”
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“…In many of these organisms the slight extent or absence of serum lysis or even bactericidal action would point in this direction, and here the appearance of proteotoxin would be secondary in importance or possibly absent entirely until late in severe infections. The non-specificity of the aggressive action of proteotoxin goes far toward explaining the increased susceptibility to other, secondary infections apparent during the course of many cases of typhoid fever and in some other diseases. …”
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“…On the other hand, there may be an increase in the phagocytic activity of the endothelium of the sinusoids which might take up more bacteria under these changed conditions. Several investigators have claimed, recently, that there is an increased activity of the liver endothelium following splenectomy, their experiments being directed chiefly toward determining the fate of the erythrocytes. …”
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“…Thymic enlargement does not ordinarily take place following a unilateral ablation. Severe chronic infections may sometimes bring about such a pronounced pathological involution of the thymus that the hyperplasia may be prevented. …”
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“…But the development of adhesions in several of the experiments shows that the procedures for the handling of the viscera should be perfected. 2. …”
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“…With this in view, globulin was obtained by precipitation with ammonium sulfate, and a series of guinea pigs and chickens received several intraperitoneal injections. In no instance was a globulin precipitin obtained. …”
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“…The febrile reaction varied in the animals of this series from a severe continuous fever of 104–105°F., lasting 2 to 3 months, in one instance, with a remittence during the 3rd to 5th weeks, to the acute high fever (106°F.) of 1 day's duration in the fatally infected monkey, No. 25. …”
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“…The experiments are of interest in several respects. It is clear that crystallized egg albumen is rapidly eliminated from the circulation and in the experiments cited it could no longer be detected after 18 or 19 hours. …”
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“…The foregoing would be of purely academic interest were it not for the following considerations. From several points of view cholesterin is unsatisfactory as a sensitizer for antigen. …”
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“…Generally the starch molecule is considered to be very large, to be composed of several dozens of such groups, and to have a molecular weight of 7,000 or much more. …”
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“…HCl at pH 1.8 solidifies the internal protoplasm and at pH 2.2 causes solidification only after several successive injections. The effect of the subsequent injections may be due to the neutralization of the cell-buffers by the first injection. 5. …”
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“…They bind themselves for a certain period (sometimes several years) and they are contractually not allowed to rescind from the agreement. …”
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“…This dye consists of two types: one known as SYBR-Green I which is non specific and the other named as High Resolution Melting analysis (HRM) which is highly sensitive, more accurate and stable. Several reports demonstrated that this new instrument combined with DNA intercalating dyes can be used to discriminate sequence changes in PCR amplicon without manual handling of PCR product [10,11]. …”
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“…CONCLUSIONS: After starting AD treatment, HRQoL improvements at 3 and 6 months were observed. However, several factors can negatively influence HRQoL, such as the presence of somatic and painful symptoms, the presence of any chronic medical condition or previous psychiatric illness.…”
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“…CONCLUSION: A 21 day period of modified dietary intake in accordance with the Daniel Fast is 1) well-tolerated by men and women and 2) improves several risk factors for metabolic and cardiovascular disease. …”
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“…In the past few years several studies used fMRI to investigate the human trigeminal system [12,13], with a limited subset focusing on intraoral stimulation - specifically on the dentoalveolar processes, such as lip, tongue and teeth stimulation [14] or only teeth [15-17]. …”
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“…Nevertheless, the number of cases within the clinical studies is not sufficient to determine the occurrence of rarely occurring (severe) adverse events in a reliable way. A reduction in the incidence and induced mortality through cervical cancer in Germany is not only depending on the vaccine’s clinical efficacy. …”
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“…The report assesses the efficacy of TNF-α-antagonists to down-regulate inflammation, improve functional status and prevent joint damage in RA with particular regard to the following indications: Treatment of severe, refractory and ongoing disease activity despite adequate use of conventional antirheumatic agents; and treatment of early RA before conventional treatment failure has been demonstrated. …”
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