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832921por Feld, Jordan J, Kandel, Christopher, Biondi, Mia J, Kozak, Robert A, Zahoor, Muhammad Atif, Lemieux, Camille, Borgia, Sergio M, Boggild, Andrea K, Powis, Jeff, McCready, Janine, Tan, Darrell H S, Chan, Tiffany, Coburn, Bryan, Kumar, Deepali, Humar, Atul, Chan, Adrienne, O'Neil, Braden, Noureldin, Seham, Booth, Joshua, Hong, Rachel, Smookler, David, Aleyadeh, Wesam, Patel, Anjali, Barber, Bethany, Casey, Julia, Hiebert, Ryan, Mistry, Henna, Choong, Ingrid, Hislop, Colin, Santer, Deanna M, Lorne Tyrrell, D, Glenn, Jeffrey S, Gehring, Adam J, Janssen, Harry L A, Hansen, Bettina E“…The primary endpoint was the proportion of patients who were negative for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA on day 7 after the injection, analysed by a χ(2) test following an intention-to-treat principle. …”
Publicado 2021
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832922por van Dam, Peter, Huizing, Manon, Roelant, Ella, Hotterbeekx, An, De Winter, Fien H.R., Kumar-Singh, Samir, Moons, Pieter, Amajoud, Zainab, Vulsteke, Christof, Croes, Lieselot, Janssens, Annelies, Berneman, Zwi, Prenen, Hans, Meuris, Leander, Vanden Berghe, Wim, Smits, Evelien, Peeters, Marc“…Better knowledge of the seroprevalence and immune response after Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection in this population is important to manage them safely during the pandemic. …”
Publicado 2021
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832923por Iwalokun, Bamidele Abiodun, Olalekan, Adesola, Adenipekun, Eyitayo, Ojo, Olabisi, Iwalokun, Senapon Olusola, Mutiu, Bamidele, Orija, Oluseyi, Adegbola, Richard, Salako, Babatunde, Akinloye, Oluyemi“…Data analyses, which include a test of association between VDR gene polymorphisms and study outcomes (lymphopenia and hypovitaminosis D prevalence, mild/moderate and severe infections) will be performed using the R statistical software. …”
Publicado 2021
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832924por Blauvelt, Andrew, Leonardi, Craig L., Gaylis, Norman, Jauch-Lembach, Julia, Balfour, Alison, Lemke, Lena, Hachaichi, Sohaib, Brueckmann, Ines, Festini, Teodora, Wiland, Piotr“…The effect of SDZ-ADL on quality of life (QoL) and patient-reported outcomes (PROs) was assessed as part of two phase III studies, one in patients with moderate‐to‐severe chronic plaque psoriasis (PsO; ADACCESS) and the other in patients with rheumatoid arthritis (RA; ADMYRA). …”
Publicado 2021
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832925por Jones, Laura, Tan, Laura, Carey-Jones, Suzanne, Riddell, Nathan, Davies, Richard, Brownsdon, Ashleigh, Kelson, Mark, Williams-Thomas, Rhys, Busse, Monica, Davies, Michael M., Morgan, Matt P. G.“…BACKGROUND: Consumer wrist-worn wearable activity monitors are widely available, low cost and are able to provide a direct measurement of several markers of physical activity. Despite this, there is limited data on their use in perioperative risk prediction. …”
Publicado 2021
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832926por Luzi, Livio, Carruba, Michele, Crialesi, Roberta, Da Empoli, Stefano, Dagani, Regina, Lovati, Elisabetta, Nicolucci, Antonio, Berra, Cesare C., Cipponeri, Elisa, Vaccaro, Ketty, Lenzi, Andrea“…HYPOTHESIS AND DISCUSSION: The increase in diabetes and obesity prevalence in Milano Metropolitan Area, which took place over 30 years, is related to several environmental factors. We hypothesize that some of those factors may have also determined the high incidence and virulence of COVID-19 in the Milano area. …”
Publicado 2021
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832927por Mahmood, Abda, Needham, Kelly, Shakur-Still, Haleema, Harris, Tim, Jamaluddin, Sabariah Faizah, Davies, David, Belli, Antonio, Mohamed, Fatahul Laham, Leech, Caroline, Lotfi, Hamzah Mohd, Moss, Phil, Lecky, Fiona, Hopkins, Philip, Wong, Darin, Boyle, Adrian, Wilson, Mark, Darwent, Melanie, Roberts, Ian“…We planned to conduct sensitivity analyses excluding patients who were severely injured at baseline. Dichotomous outcomes were analysed using relative risks (RR) or hazard ratios (HR), and continuous outcomes using a linear mixed model. …”
Publicado 2021
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832928Patient Use and Clinical Practice Patterns of Remote Cardiology Clinic Visits in the Era of COVID-19por Yuan, Neal, Pevnick, Joshua M., Botting, Patrick G., Elad, Yaron, Miller, Shaun J., Cheng, Susan, Ebinger, Joseph E.“…CONCLUSIONS AND RELEVANCE: Patients who were Asian, Black, or Hispanic, had private insurance, and had at least one of several cardiovascular comorbidities used remote cardiovascular care more frequently in the COVID-era period. …”
Publicado 2021
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832929por Finelli, Lyn, Gupta, Vikas, Petigara, Tanaz, Yu, Kalvin, Bauer, Karri A., Puzniak, Laura A.“…IMPORTANCE: Mortality is an important measure of the severity of a pandemic. This study aimed to understand how mortality by age of hospitalized patients who were tested for SARS-CoV-2 has changed over time. …”
Publicado 2021
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832930por Benkirane, H., Heikel, J., Laamiri, F.Z., Bouziani, A., Lahmam, H., Al-Jawaldeh, A., El Haloui, N., Ennibi, K., Akhtar-Khan, N., El Fahime, E.M., Barkat, A., Aguenaou, H.“…INTRODUCTION ET BUT DE L’ÉTUDE: L’épidémie de coronavirus-2 du syndrome respiratoire aigu sévère (SRAS-CoV-2), à l’origine de la maladie à coronavirus 2019 (COVID-19), présente une menace importante et urgente pour la santé mondiale. …”
Publicado 2021
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832931por Koch, Aleksander, Krasny, Joanna, Dziurda, Magdalena, Ratajczyk, Magdalena, Jozwiak, Marek“…Methods: Radiological evaluation was based on a standardized anteroposterior X-ray of the hip joints. Pain severity before surgery and at the last follow-up time was measured by visual analog scale-11. …”
Publicado 2021
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832932por Rubin, Geoffrey A., Desai, Amar D., Chai, Zilan, Wang, Aijin, Chen, Qixuan, Wang, Amy S., Kemal, Cameron, Baksh, Haajra, Biviano, Angelo, Dizon, Jose M., Yarmohammadi, Hirad, Ehlert, Frederick, Saluja, Deepak, Rubin, David A., Morrow, John P., Avula, Uma Mahesh R., Berman, Jeremy P., Kushnir, Alexander, Abrams, Mark P., Hennessey, Jessica A., Elias, Pierre, Poterucha, Timothy J., Uriel, Nir, Kubin, Christine J., LaSota, Elijah, Zucker, Jason, Sobieszczyk, Magdalena E., Schwartz, Allan, Garan, Hasan, Waase, Marc P., Wan, Elaine Y.“…Multivariable analysis revealed that age 80 years and older compared with those younger than 50 years (mean difference in QTc, 11.91 [SE, 4.69; 95% CI, 2.73 to 21.09]; P = .01), severe chronic kidney disease compared with no chronic kidney disease (mean difference in QTc, 12.20 [SE, 5.26; 95% CI, 1.89 to 22.51; P = .02]), elevated high-sensitivity troponin levels (mean difference in QTc, 5.05 [SE, 1.19; 95% CI, 2.72 to 7.38]; P < .001), and elevated lactate dehydrogenase levels (mean difference in QTc, 5.31 [SE, 2.68; 95% CI, 0.06 to 10.57]; P = .04) were associated with QTc prolongation. …”
Publicado 2021
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832933por Hayes, Joseph F., Osborn, David P. J., Francis, Emma, Ambler, Gareth, Tomlinson, Laurie A., Boman, Magnus, Wong, Ian C. K., Geddes, John R., Dalman, Christina, Lewis, Glyn“…Of these, 168 (87.96%) and 117 (85.40%) respectively developed CKD 3a or more severe during follow-up. The model, developed in Aurum, had a ROC area of 0.879 (95%CI 0.853–0.904) in the Gold external validation data set. …”
Publicado 2021
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832934por Bowman, Clive E.“…Almost invariably within an overall body size class, the switch in predatory style from a worm-like prey feeding (‘crushing/mashing’ kill) functional group to a micro-arthropod feeding (‘active prey cutting/slicing/slashing' kill) functional group is matched by: an increased cheliceral reach, a bigger chelal gape, a larger morphologically estimated chelal crunch force, and a drop in the adductive lever arm velocity ratio of the chela. Small size matters. Several uropodines (Eviphis ostrinus, the omnivore Trachytes aegrota, Urodiaspis tecta and, Uropoda orbicularis) have more elongate chelicerae (greater reach) than their chelal gape would suggest, even allowing for allometry across mesostigmatids. …”
Publicado 2021
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832935por Povaliaeva, Alexandra, Rozhinskaya, Liudmila Ya, Pigarova, Ekaterina A, Dzeranova, Larisa K, Katamadze, Nino N, Malysheva, Natalya, Nikankina, Larisa, Bogdanov, Viktor, Ioutsi, Vitaliy, Mokrysheva, Natalia G“…The observed profound vitamin D deficiency and association of vitamin D levels with markers of disease severity indicate the importance of vitamin D supplementation in these patients.…”
Publicado 2021
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832936por Buckingham, Bruce A, Forlenza, Gregory P, Criego, Amy B, Hansen, David W, Bode, Bruce W, Brown, Sue A, MacLeish, Sarah A, Pinsker, Jordan E, DeSalvo, Daniel J, Sherr, Jennifer L, Mehta, Sanjeev N, Laffel, Lori M, Bhargava, Anuj, Ly, Trang T“…The primary safety and effectiveness endpoints, respectively, were occurrence of severe hypoglycemia (SH) and diabetic ketoacidosis (DKA), and change in A1C and sensor glucose percent time in target range (TIR) (70–180 mg/dL) during HCL compared with ST. …”
Publicado 2021
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832937“…Worldwide most prescribing NASID drug shows severe side effects. Whereas drug from natural origin shows dual inhibition of inflammatory and analgesic target protein with more efficacy and less side effects than NSAID drugs. …”
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832938por Kadiyala, Suneetha, Harris-Fry, Helen, Pradhan, Ronali, Mohanty, Satyanarayan, Padhan, Shibanath, Rath, Suchitra, James, Philip, Fivian, Emily, Koniz-Booher, Peggy, Nair, Nirmala, Haghparast-Bidgoli, Hassan, Mishra, Naba Kishor, Rath, Shibanand, Beaumont, Emma, Danton, Heather, Krishnan, Sneha, Parida, Manoj, O'Hearn, Meghan, Kumar, Abhinav, Upadhyay, Avinash, Tripathy, Prasanta, Skordis, Jolene, Sturgess, Joanna, Elbourne, Diana, Prost, Audrey, Allen, Elizabeth“…These components have been implemented separately in several low-income settings; effects could be increased by scaling up together. …”
Publicado 2021
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832939por Jeyam, Anita, Gibb, Fraser W., McKnight, John A., Kennon, Brian, O’Reilly, Joseph E., Caparrotta, Thomas M., Höhn, Andreas, McGurnaghan, Stuart J., Blackbourn, Luke A. K., Hatam, Sara, McCrimmon, Rory J., Leese, Graham, Lindsay, Robert S., Petrie, John, Chalmers, John, Philip, Sam, Wild, Sarah H., Sattar, Naveed, McKeigue, Paul M., Colhoun, Helen M.“…AIMS/HYPOTHESIS: Our aim was to assess the use of continuous subcutaneous insulin infusion (CSII) in people with type 1 diabetes in Scotland and its association with glycaemic control, as measured by HbA(1c) levels, frequency of diabetic ketoacidosis (DKA) and severe hospitalised hypoglycaemia (SHH), overall and stratified by baseline HbA(1c). …”
Publicado 2021
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832940por Lund, Lars Christian, Hallas, Jesper, Nielsen, Henrik, Koch, Anders, Mogensen, Stine Hasling, Brun, Nikolai Constantin, Christiansen, Christian Fynbo, Thomsen, Reimar Wernich, Pottegård, Anton“…INTERPRETATION: The absolute risk of severe post-acute complications after SARS-CoV-2 infection not requiring hospital admission is low. …”
Publicado 2021
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