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833161por Bazdyrev, Evgeny, Panova, Maria, Brachs, Maria, Smolyarchuk, Elena, Tsygankova, Daria, Gofman, Liudmila, Abdyusheva, Yana, Novikov, Fedor“…Patients with a diagnosis of COVID in the past medical history (with the first symptoms of COVID appear no earlier than 2 months before screening) and having fibrotic changes in the lungs, decreased lung function (percentage of predicted FVC and/or DLCO < 80%), and moderate or severe dyspnea according to mMRC scale were enrolled and randomly assigned in a 1:1 ratio (stratified by the initial degree of lung damage, age, and concomitant chronic diseases) by use of interactive responsive technology to peroral administration of Treamid 50 mg or placebo once a day for 4 weeks. …”
Publicado 2022
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833162por Eikelboom, John W, Jolly, Sanjit S, Belley-Cote, Emilie P, Whitlock, Richard P, Rangarajan, Sumathy, Xu, Lizhen, Heenan, Laura, Bangdiwala, Shrikant I, Luz Diaz, Maria, Diaz, Rafael, Yusufali, Afzalhussein, Kumar Sharma, Sanjib, Tarhuni, Wadea M, Hassany, Mohamed, Avezum, Alvaro, Harper, William, Wasserman, Sean, Almas, Aysha, Drapkina, Oxana, Felix, Camilo, Lopes, Renato D, Berwanger, Otavio, Lopez-Jaramillo, Patricio, Anand, Sonia S, Bosch, Jackie, Choudhri, Shurjeel, Farkouh, Michael E, Loeb, Mark, Yusuf, Salim“…Results were consistent in subgroups defined by vaccination status, disease severity at baseline, and timing of randomisation in relation to onset of symptoms. …”
Publicado 2022
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833163por Alkhalil, Munzer, Alaref, Maher, Mkhallalati, Hala, Alzoubi, Zedoun, Ekzayez, Abdulkarim“…The health system was severely affected and has become aid dependent. This study examines aid alignment over a decade of the Syrian crisis from 2011 to 2019. …”
Publicado 2022
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833164por Wurm, Juliane, Lehfeld, Ann-Sophie, Varnaccia, Gianni, Iwanowski, Helena, Finkel, Bianca, Schienkiewitz, Anja, Perlitz, Hanna, Loer, Anne-Kathrin Mareike, Wess, Barbara, Franke, Andrea, Hüther, Antje, Kuttig, Tim, Sandoni, Anna, Kubisch, Ulrike, Jordan, Susanne, Haas, Walter, Buchholz, Udo, Loss, Julika“…From the surveillance data (CATS), clinical information was available for 84,371 SARS-CoV‑2 positive children; fever was most common (27%) along with rhinitis (26%). Severe symptoms such as dyspnea were rarely reported in the outbreak investigations and in the surveillance data (3% and 1%, respectively). …”
Publicado 2022
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833165por Amuge, Pauline, Lugemwa, Abbas, Wynne, Ben, Mujuru, Hilda A, Violari, Avy, Kityo, Cissy M, Archary, Moherndran, Variava, Ebrahim, White, Ellen, Turner, Rebecca M, Shakeshaft, Clare, Ali, Shabinah, Nathoo, Kusum J, Atwine, Lorna, Liberty, Afaaf, Bbuye, Dickson, Kaudha, Elizabeth, Mngqibisa, Rosie, Mosala, Modehei, Mumbiro, Vivian, Nanduudu, Annet, Ankunda, Rogers, Maseko, Lindiwe, Kekitiinwa, Adeodata R, Giaquinto, Carlo, Rojo, Pablo, Gibb, Diana M, Turkova, Anna, Ford, Deborah“…The primary outcome was the Kaplan-Meier estimated proportion of children with virological or clinical failure by 96 weeks, defined as: confirmed viral load of at least 400 copies per mL after week 36; absence of virological suppression by 24 weeks followed by a switch to second-line or third-line ART; all-cause death; or a new or recurrent WHO stage 4 or severe WHO stage 3 event. The primary outcome was assessed by intention to treat in all randomly assigned participants. …”
Publicado 2022
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833166por Bergeri, Isabel, Whelan, Mairead G., Ware, Harriet, Subissi, Lorenzo, Nardone, Anthony, Lewis, Hannah C., Li, Zihan, Ma, Xiaomeng, Valenciano, Marta, Cheng, Brianna, Al Ariqi, Lubna, Rashidian, Arash, Okeibunor, Joseph, Azim, Tasnim, Wijesinghe, Pushpa, Le, Linh-Vi, Vaughan, Aisling, Pebody, Richard, Vicari, Andrea, Yan, Tingting, Yanes-Lane, Mercedes, Cao, Christian, Clifton, David A., Cheng, Matthew P., Papenburg, Jesse, Buckeridge, David, Bobrovitz, Niklas, Arora, Rahul K., Van Kerkhove, Maria D.“…BACKGROUND: Our understanding of the global scale of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection remains incomplete: Routine surveillance data underestimate infection and cannot infer on population immunity; there is a predominance of asymptomatic infections, and uneven access to diagnostics. …”
Publicado 2022
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833167por Zahir, Hamim, Greenberg, Jonathan, Shuster, Dale, Hsu, Ching, Watanabe, Kengo, LaCreta, Frank“…It is approved in the United States for the treatment of adult patients with symptomatic tenosynovial giant cell tumor (TGCT) associated with severe morbidity or functional limitations and not amenable to improvement with surgery. …”
Publicado 2022
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833168“…Graphene nanosheets and their hybrid materials with molybdenum disulfide or zinc oxide nanoparticles have been applied to dispersive solid-phase extraction, and several types of contaminants, including metal ions, bisphenol endocrine disruptors, paraben preservatives, and phthalates, could be captured. …”
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833169por Lund, Hans, Robinson, Karen A., Gjerland, Ane, Nykvist, Hanna, Drachen, Thea Marie, Christensen, Robin, Juhl, Carsten Bogh, Jamtvedt, Gro, Nortvedt, Monica, Bjerrum, Merete, Westmore, Matt, Yost, Jennifer, Brunnhuber, Klara“…BACKGROUND: Several studies have documented the production of wasteful research, defined as research of no scientific importance and/or not meeting societal needs. …”
Publicado 2022
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833170por Pehlivan, Melissa J., Miskovic-Wheatley, Jane, Le, Anvi, Maloney, Danielle, Research Consortium, National Eating Disorders, Touyz, Stephen, Maguire, Sarah“…RESULTS: Sixty-three studies (4.5% of the original RR) were identified, which included several diagnostic populations, the most common being Anorexia Nervosa (AN) (30.51%). …”
Publicado 2022
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833171por Popescu, Mihai, Olita, Mihaela Roxana, Stefan, Mara Oana, Mihaila, Mariana, Sima, Romina-Marina, Tomescu, Dana“…The observed changes are more severe and longer-lasting in patients undergoing robotic-assisted surgery compared to classic laparoscopy. …”
Publicado 2022
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833172por Yuan, Huiqing, Zhang, Cui, Maung, Ei Ni Tar, Fan, Songli, Shi, Zijia, Liao, Fang, Wang, Shuo, Jin, Ying, Chen, Le, Wang, Li“…The results of multivariate Logistic regression analysis after the Universal Two-Child Policy showed that anemia (OR = 1.249, 95%CI: 1.071–1.458), chronic hypertension (OR = 1.934, 95%CI: 1.375–2.722), mild preeclampsia (OR = 2.103, 95%CI: 1.323–3.344) and severe preeclampsia (OR = 2.228, 95%CI: 1.703–2.916) were independent risk factors for obstetric infection. …”
Publicado 2022
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833173por Krekeler, Carolin, Reitnauer, Lea, Bacher, Ulrike, Khandanpour, Cyrus, Steger, Leander, Boeckel, Göran Ramin, Klosner, Justine, Tepasse, Phil-Robin, Kemper, Marcel, Hennies, Marc Tim, Mesters, Rolf, Stelljes, Matthias, Schmitz, Norbert, Kerkhoff, Andrea, Schliemann, Christoph, Mikesch, Jan-Henrik, Schmidt, Nicole, Lenz, Georg, Bleckmann, Annalen, Shumilov, Evgenii“…Booster failure can likely be overcome by passive immunization, thereby providing immune protection against COVID-19 and attenuating the severity of COVID-19 courses. Further sophistication of clinical algorithms for preventing post-vaccination COVID-19 breakthrough infections is urgently needed.…”
Publicado 2022
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833174por Bilski, Mateusz, Cisek, Paweł, Baranowska, Izabela, Kordzińska-Cisek, Izabela, Komaniecka, Nina, Hymos, Anna, Grywalska, Ewelina, Niedźwiedzka-Rystwej, Paulina“…The unquestionable advantage of contact brachytherapy is its ability to be performed on an outpatient basis without the need to stay in the hospital. No severe and late CTCAE ≥III and late RTOG ≥III toxicity was observed. …”
Publicado 2022
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833175por Li, Yue, Long, Ze, Wang, Xiuju, Lei, Mingxing, Liu, Chunzi, Shi, Xiaolin, Liu, Yaosheng“…Additionally, patients with poor quality of life experience more severe anxiety and depression. Effective interventions should be carried out as soon as possible, especially for patients in the high-risk group, to improve their quality of life and mental health condition. …”
Publicado 2022
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833176por Redondo, Maria J., Richardson, Sarah J., Perry, Daniel, Minard, Charles G., Carr, Alice L. J., Brusko, Todd, Kusmartseva, Irina, Pugliese, Alberto, Atkinson, Mark A.“…CONCLUSIONS/INTERPRETATION: Overall, these data support the presence of a type 1 diabetes endotype associated with a genetic factor that predisposes to type 2 diabetes, with donors in this category exhibiting less severe beta cell loss. It is possible that in these individuals the disease pathogenesis may include mechanisms associated with type 2 diabetes and thus this may provide an explanation for the poor response to immunotherapies to prevent type 1 diabetes or its progression in a subset of individuals. …”
Publicado 2022
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833177por Manaa, L., Aounallah, A., Salah, N. Ben, Gaied, M. Lahoual Ep, Fetoui, N. Ghariani, Mokni, S., Ghariani, N., Sriha, B., Belajouza, C., Denguezli, M.“…Il était hospitalisé en pneumologie en juillet 2021 pour une infection sévère COVID-19. Vingt jours après, il a présenté des lésions violacées s’étendant progressivement au niveau du tronc et des membres. …”
Publicado 2022
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833178“…Leur sensibilité aux infections diffère aussi: lien étroit entre poussées de DA et infection à staphylocoque, infections herpétiques sévères et molluscums plus fréquents dans la DA, alors que le psoriasis est surtout associé à des poussées inflammatoires post-infectieuses, essentiellement streptococciques. …”
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833179“…Parmi les patients, 66 (79,6 %) avaient eu une infection au SARS-CoV-2 asymptomatique, 18,4 % avaient des symptômes légers et seulement 1 patiente avait été hospitalisée dans un service de soins intensifs pour infection sévère ; 52 patients (38,2 %) étaient sous traitement systémique, 22 (42,3 %) ont dû arrêter leurs traitements au cours de l’infection par inquiétude. …”
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833180“…DISCUSSION/CONCLUSION: La PEC du PIMS s’est inspirée de la forme sévère de la maladie de Kawasaki, recommandant l’utilisation d’IgPv hors AMM, médicaments remboursés en sus du groupe homogène de séjour. …”
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