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  1. 833341
    “…BACKGROUND: Morphine is commonly used to treat severe pain. This substance is significantly metabolized in the liver and causes disturbing effects. …”
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    Genistein Improves Liver Damage in Male Mice Exposed to Morphine
  2. 833342
    “…The risk of revision for PJI was marginally or not influenced by the grade of the operating surgeon, the absence of a consultant surgeon during surgey, and the volume of procedures performed by hospital or surgeon. INTERPRETATION: Several modifiable and non-modifiable factors are associated with the risk of revision for PJI after primary hip replacement. …”
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    Risk factors associated with revision for prosthetic joint infection after hip replacement: a prospective observational cohort study
  3. 833343
    “…To enhance the shelf life, milk is subjected to Ultra-high Temperature (UHT) treatment followed by aseptic packaging. During the storage, several chemical and biochemical changes take place in lipid fraction of UHT milk. …”
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    Lipid compositional changes and oxidation status of ultra-high temperature treated Milk
  4. 833344
    “…Grade 2 or higher ISRs were the only AEs reported more commonly among CAB LA recipients than PBO recipients. Two Grade 3 (severe) ISRs occurred in CAB recipients, 1 in each cohort, but did not lead to product discontinuation in either case. …”
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    Safety, tolerability, and pharmacokinetics of long-acting injectable cabotegravir in low-risk HIV-uninfected individuals: HPTN 077, a phase 2a randomized controlled trial
  5. 833345
    “…Reproduction was assessed using pregnancy rate and progesterone measurements. There were several treatment effects on aggression in the sows following mixing. …”
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    Feeding Strategies Before and at Mixing: The Effect on Sow Aggression and Behavior
  6. 833346
    por von Seidlein, Lorenz, Peto, Thomas J., Landier, Jordi, Nguyen, Thuy-Nhien, Tripura, Rupam, Phommasone, Koukeo, Pongvongsa, Tiengkham, Lwin, Khin Maung, Keereecharoen, Lilly, Kajeechiwa, Ladda, Thwin, May Myo, Parker, Daniel M., Wiladphaingern, Jacher, Nosten, Suphak, Proux, Stephane, Corbel, Vincent, Tuong-Vy, Nguyen, Phuc-Nhi, Truong Le, Son, Do Hung, Huong-Thu, Pham Nguyen, Tuyen, Nguyen Thi Kim, Tien, Nguyen Thanh, Dong, Le Thanh, Hue, Dao Van, Quang, Huynh Hong, Nguon, Chea, Davoeung, Chan, Rekol, Huy, Adhikari, Bipin, Henriques, Gisela, Phongmany, Panom, Suangkanarat, Preyanan, Jeeyapant, Atthanee, Vihokhern, Benchawan, van der Pluijm, Rob W., Lubell, Yoel, White, Lisa J., Aguas, Ricardo, Promnarate, Cholrawee, Sirithiranont, Pasathorn, Malleret, Benoit, Rénia, Laurent, Onsjö, Carl, Chan, Xin Hui, Chalk, Jeremy, Miotto, Olivo, Patumrat, Krittaya, Chotivanich, Kesinee, Hanboonkunupakarn, Borimas, Jittmala, Podjanee, Kaehler, Nils, Cheah, Phaik Yeong, Pell, Christopher, Dhorda, Mehul, Imwong, Mallika, Snounou, Georges, Mukaka, Mavuto, Peerawaranun, Pimnara, Lee, Sue J., Simpson, Julie A., Pukrittayakamee, Sasithon, Singhasivanon, Pratap, Grobusch, Martin P., Cobelens, Frank, Smithuis, Frank, Newton, Paul N., Thwaites, Guy E., Day, Nicholas P. J., Mayxay, Mayfong, Hien, Tran Tinh, Nosten, Francois H., Dondorp, Arjen M., White, Nicholas J.
    Publicado 2019
    “…The DP MDAs were well tolerated; 6 severe adverse events were detected during the follow-up period, but none was attributable to the intervention. …”
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    The impact of targeted malaria elimination with mass drug administrations on falciparum malaria in Southeast Asia: A cluster randomised trial
  7. 833347
    por Rydahl, Eva, Eriksen, Lena, Juhl, Mette
    Publicado 2019
    “…CONCLUSIONS: Induction prior to post-term was associated with few beneficial outcomes and several adverse outcomes. This draws attention to possible iatrogenic effects affecting large numbers of low-risk women in contemporary maternity care. …”
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    Effects of induction of labor prior to post-term in low-risk pregnancies: a systematic review
  8. 833348
    “…Although xenotransplantation of ITT from several species has resulted in complete spermatogenesis, in human and marmoset, ITT has not been successful. …”
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    Complete spermatogenesis in intratesticular testis tissue xenotransplants from immature non-human primate
  9. 833349
    “…Depression may antedate a diagnosis of IBD by several years and increase post-diagnosis. High stress can exacerbate symptoms in IBD but does not necessarily increase bowel inflammation. 12. …”
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    The Impact of Inflammatory Bowel Disease in Canada 2018: Extra-intestinal Diseases in IBD
  10. 833350
    “…Collectively, these data should provide physicians and health-care professionals with reassuring experimental-based evidence for counselling of male cancer patients contemplating their reproductive options several years after treatment. STUDY FUNDING/COMPETING INTEREST(S): This work was primarily supported by grants from the Wellcome (grant 091182 to AG and AOMW; grant 102 731 to AOMW), the University of Oxford Medical Sciences Division Internal Fund (grant 0005128 to GJM and AG), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre Programme (to AG) and the US National Institutes of Health (to MLM). …”
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    The impact of chemo- and radiotherapy treatments on selfish de novo FGFR2 mutations in sperm of cancer survivors
  11. 833351
    “…Participants were randomly assigned (1:1:1) to either 6 months of usual care (usual care group), daily self-managed CSLT plus usual care (CSLT group), or attention control plus usual care (attention control group) with the use of computer-generated stratified blocked randomisation (randomly ordered blocks of sizes three and six, stratified by site and severity of word finding at baseline based on CAT Naming Objects test scores). …”
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    Self-managed, computerised speech and language therapy for patients with chronic aphasia post-stroke compared with usual care or attention control (Big CACTUS): a multicentre, single-blinded, randomised controlled trial
  12. 833352
    “…However, this patient is unique in several ways. He presented mainly with episodes of inflammatory polyarthritis of large and small joints which was diagnosed as rheumatoid arthritis, because he did not have the usual constitutional symptoms (fever, weight loss, fatigue, and arthralgia) that are characteristic of the inflammatory phase of TA. …”
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    31. Takayasu arteritis presenting as bilateral popliteal artery aneurysm: a rare presentation of a rare disease
  13. 833353
    “…He was readmitted after six weeks with pyrexia and severe chest pain. A CT of his thoracic aorta showed further expansion of the aortic aneurysm, 59mm with a slightly thickened abdominal aorta wall. …”
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    42. Large vessel vasculitis with rapidly expanding aortic aneurysm
  14. 833354
    “…KEY LEARNING POINTS: This case sheds light on LVV through several interesting perspectives. Firstly, it is unusual for LVV to present with claudication in the lower limbs in the absence of aortitis, demonstrating the variety of ways in which the same pathophysiological mechanism can present clinically. …”
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    18. An unusual PET project: large vessel vasculitis presenting as lower limb claudication in the absence of aortitis
  15. 833355
    por Patel, Samir, Al-Shakarchi, Israa
    Publicado 2019
    “…The patient had a negative PET scan despite progression to severe disease within 1 month. PET studies have shown high sensitivity and specificity values for the diagnosis of large vessel inflammation in GCA (90% and 98% respectively – Soussan et al., 2015). …”
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    51. An atypical case of GCA: an innocuous presentation ending with ophthalmic complications and cerebral vasculitis
  16. 833356
    por Hoey, Mark, McHenry, Michelle
    Publicado 2019
    “…During this case the patient for several months described myalgia, muscle weakness and fatigue which responded to steroids. …”
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    15. Myalgia resulting from fasciitis in a difficult to diagnose case of dermatomyositis
  17. 833357
    “…Temporal headache, visual symptoms, jaw claudication characterise the GCA, and persistent severe headache can be a manifestation of cerebral lupus in patient who has the diagnosis of SLE. …”
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    19. A case of giant cell arteritis (GCA) co-existent with systemic lupus erythematosus (SLE)/rheumatoid arthritis (RA) overlap syndrome
  18. 833358
    “…Electrophysiology showed chronic neurogenic changes of moderate severity in predominately L4 innervated muscles – vastus medialis and adductor magnus of the right lower limb. …”
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    5. All That glitters is not gold
  19. 833359
    por Oke, Anuoluwapo, Dunne, Ciaran
    Publicado 2019
    “…The reason for submitting this case is to raise awareness of an atypical presentation of an uncommon, often severe and chronic illness. CASE DESCRIPTION: A forty-seven-year-old female of Irish and French descent presented with a six months history of bilateral episcleritis, generalised myalgia, arthralgia (knees, ankles, and elbows), recurrent oral ulceration, and skin rash over her shin, hands and chest, weight loss and fatigue. …”
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    34. An unusual presentation of a cervical mass
  20. 833360
    “…Firstly, this lady failed to respond to IL-1 receptor antagonist anakinra which has been associated with efficacy in several reports for individuals with TRAPS, and has supplanted TNF blockade with agents such as etanercept for this condition. …”
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    9. Successful use of IL-6 pathway blockade to treat autoinflammation occurring in the context of a novel TNFRS1A gene mutation
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