“…Fifteen days after admission, she developed severe type-1 respiratory failure requiring transfer to intensive care. …”
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“…Herein, we present a case of SLE in a young male in which bullous skin disease was the index symptom of a severe and rapidly evolving presentation associated with multi-organ involvement that was successfully treated with cyclophosphamide. …”
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“…Background: Oral octreotide capsules (OOC) are a treatment option for patients with acromegaly in several countries. Global MPOWERED trial (NCT02685709; Fleseriu et al, Lancet Diabetes Endocrinol. 2022; 10: 102-111)(1) showed that OOC were noninferior to injectable somatostatin receptor ligands (iSRLs; octreotide or lanreotide) in maintenance of biochemical response in those previously responding to both OOC and iSRLs. …”
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“…PIV measurements were collected at Intensive Care Unit (ICU) admission, and several mortality measures were examined. To control for potential confounding effects, a 1:1 propensity score matching (PSM) method was applied. …”
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“…Following a near absence in 2020-21, RSV hospitalizations increased in the 2021-22 season, but severity of illness remained similar to the pre-pandemic period. …”
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“…BACKGROUND: Nirsevimab is an extended half-life monoclonal antibody (mAb) newly authorized for the prevention of respiratory syncytial virus (RSV) lower respiratory tract disease in infants born during or entering their first RSV season, and in children up to 24 months of age who remain vulnerable to severe disease through their second season. Anti-RSV mAbs are currently assessed based on their direct virus neutralization activity in the absence of a well-established correlate of protection. …”
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“…BACKGROUND: Nonvenereal treponemal (NVT) infections (Bejel, Yaws, and Pinta) are historically a major health concern in developing countries(1) (Figure 1), but they are increasingly ignored. NVTs can lead to severe complications. Our aim was to highlight disease characteristics, treatments, and outcomes, and to identify drug repurposing by curating all cases of NVTs in the literature in CURE ID(4), a platform that catalogs real-world data on drug repurposing for difficult-to-treat infectious diseases. …”
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“…An intact intestinal microbiome suppresses expansion of enteric pathogens, however patients with severe liver disease often have reduced microbiome diversity and increased density of antibiotic-resistant Enterococcus and Enterobacterales species. …”
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“…This persistent humoral reaction may be driven by persistent antigenic stimulation by p53 protein derived from overexpression of p53 at distant metastatic sites; alternatively, irradiated normal tissue may be a source of continued antigenic stimulation, because a long-term side effect of radiation therapy is an increased expression of p53 in normal breast tissue that persists for several years [12]. Since the great majority of our total patient cohort had received radiotherapy, humoral immunity to p53 associated with primary disease might persist, even in those patients who enter remission, due to tumour-independent antigenic stimulation. …”
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“…The kruskal-Wallis test for several group means was used to compare the percentage of TUNEL-positive cells at different time points. …”
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“…While in the exudate of the lesion produced by the virulent streptococcus the amount was perceptibly larger than the insignificant amount present in the lesion caused by a slightly virulent strain, it is not to be compared with the large amount of fibrin which exists in the exudate of pneumococcus pneumonia. The several investigations which we have carried out seem to show conclusively that in general the streptococcus causes a lobular pneumonia which, besides the leucocytic intra-alveolar exudation, is characterized by a leucocytic infiltration of the lung framework, and that the pneumococcus causes a lobar pneumonia, which is practically free from leucocytic infiltration of the interstitial tissue of the lung. …”
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“…Additional evidence of this action of the white blood cell is furnished by further experiments with actively immunized aplastic rabbits. Several immunized rabbits were benzolized and then injected with a lethal dose of pneumococci. …”
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“…Indeed, the experiment by which acute injury is produced in the normal guinea pig by the sudden injection of several times the lethal dose of partly dissolved bacteria, finds no analogy in the spontaneously diseased body. …”
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“…Regardless of elaborate serological studies and animal experiments, streptococci must be recovered consistently by several groups of laboratory workers before their etiologic rôle in chronic arthritis and rheumatic fever can be accepted. …”
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“…There is a risk factor for gastric or duodenal ulcers, gastric cancer and MALT (Mucosa Associated Lymphoid Tissue)-Lymphomas. There are several invasive and non-invasive methods available for the diagnosis of H. pylori. …”
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“…BACKGROUND: The condition of non-specific back pain is characterized by high prevalence, non satisfactory therapeutic options and severe socioeconomic consequences. Therefore prevention seems an attractive option to downsize the problem. …”
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“…In addition to the core institutes, PhD students from several other high-profile institutes are invited to attend the conference. …”
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“…CONCLUSIONS: To increase IRS acceptance, participants recommended more emphasis on providing thorough public education, ensuring the sprayers themselves are more knowledgeable about IRS, and asking that community leaders encourage participation by their constituents rather than threatening punishment for noncompliance. While there are several rumours and misconceptions concerning IRS in Tanzania, acceptance is very high and continues to increase as positive results become apparent. …”
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“…Based on these results Septoria is shown to be a distinct genus in the Mycosphaerellaceae, which has mycosphaerella-like sexual morphs. Several septoria-like species are now accommodated in Sphaerulina, a genus previously linked to this complex. …”
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“…S.G. experienced a 3-week treatment break due to severe radiation dermatitis, as recommended by her outside treating oncologist. …”
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