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  1. 833621
    “…Twenty-nine randomised controlled trials were identified, with differences in their methodological quality; 21 trials involving over 17,000 women contributing data to the review. Several minutes were saved when the peritoneum was not stitched, and with a shorter period of hospital stay in most of the women. …”
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    Closure versus non-closure of the peritoneum at caesarean section: short- and long-term outcomes
  2. 833622
    por Newton, John N, Briggs, Adam D M, Murray, Christopher J L, Dicker, Daniel, Foreman, Kyle J, Wang, Haidong, Naghavi, Mohsen, Forouzanfar, Mohammad H, Ohno, Summer Lockett, Barber, Ryan M, Vos, Theo, Stanaway, Jeffrey D, Schmidt, Jürgen C, Hughes, Andrew J, Fay, Derek F J, Ecob, Russell, Gresser, Charis, McKee, Martin, Rutter, Harry, Abubakar, Ibrahim, Ali, Raghib, Anderson, H Ross, Banerjee, Amitava, Bennett, Derrick A, Bernabé, Eduardo, Bhui, Kamaldeep S, Biryukov, Stanley M, Bourne, Rupert R, Brayne, Carol E G, Bruce, Nigel G, Brugha, Traolach S, Burch, Michael, Capewell, Simon, Casey, Daniel, Chowdhury, Rajiv, Coates, Matthew M, Cooper, Cyrus, Critchley, Julia A, Dargan, Paul I, Dherani, Mukesh K, Elliott, Paul, Ezzati, Majid, Fenton, Kevin A, Fraser, Maya S, Fürst, Thomas, Greaves, Felix, Green, Mark A, Gunnell, David J, Hannigan, Bernadette M, Hay, Roderick J, Hay, Simon I, Hemingway, Harry, Larson, Heidi J, Looker, Katharine J, Lunevicius, Raimundas, Lyons, Ronan A, Marcenes, Wagner, Mason-Jones, Amanda J, Matthews, Fiona E, Moller, Henrik, Murdoch, Michele E, Newton, Charles R, Pearce, Neil, Piel, Frédéric B, Pope, Daniel, Rahimi, Kazem, Rodriguez, Alina, Scarborough, Peter, Schumacher, Austin E, Shiue, Ivy, Smeeth, Liam, Tedstone, Alison, Valabhji, Jonathan, Williams, Hywel C, Wolfe, Charles D A, Woolf, Anthony D, Davis, Adrian C J
    Publicado 2015
    “…Systematic action locally and nationally is needed to reduce risk exposures, support healthy behaviours, alleviate the severity of chronic disabling disorders, and mitigate the effects of socioeconomic deprivation. …”
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    Changes in health in England, with analysis by English regions and areas of deprivation, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013
  3. 833623
    por Protasi, Feliciano
    Publicado 2015
    “…In human studies (see Figure 4), we compared samples from two groups of elderly individuals (all males): sedentary subjects (70 ± 5 years) or sportmen (69 ± 4 years of age), i.e. individuals who regularly exercised in the last several years of their lives. These studies revealed that both CRUs and mitochondria increase with exercise, mitochondria more than CRUs. …”
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    Mitochondria Association to Calcium Release Units is Controlled by Age and Muscle Activity
  4. 833624
    “…In contrast, Old-ET females displayed a greater (P < 0.05) peak glucose concentration at 30 min during the GTT (21.1 ± 0.4 versus 17.8 ± 1.16 mmol/l) and their spleen weight (88.2 ± 2.6 ± 105.1 ± 4.6 mg) and several organ:body weight ratios (g/g × 10(3)) were decreased (P < 0.05 versus Young-ET), including the heart (3.7 ± 0.06 versus 4.4 ± 0.08), lungs (4.4 ± 0.1 versus 5.0 ± 0.1), spleen (2.4 ± 0.06 versus 3.2 ± 0.1) and liver (36.4 ± 0.6 versus 39.1 ± 0.9). …”
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    Advanced maternal age causes adverse programming of mouse blastocysts leading to altered growth and impaired cardiometabolic health in post-natal life
  5. 833625
    “…The list was archived, then we randomly assigned clusters (1:1) to either immediate vaccination or delayed vaccination (21 days later) of all eligible individuals (eg, those aged ≥18 years and not pregnant, breastfeeding, or severely ill). An independent statistician generated the assignment sequence using block randomisation with randomly varying blocks, stratified by location (urban vs rural) and size of rings (≤20 individuals vs >20 individuals). …”
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    Efficacy and effectiveness of an rVSV-vectored vaccine in preventing Ebola virus disease: final results from the Guinea ring vaccination, open-label, cluster-randomised trial (Ebola Ça Suffit!)
  6. 833626
    “…AUTHORS' CONCLUSIONS: We have high or moderate confidence in the evidence contributing to several review findings. Further research, especially in rural and low‐ to middle‐income country settings, could strengthen evidence for the findings where we had low or very low confidence. …”
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    Parents' and informal caregivers' views and experiences of communication about routine childhood vaccination: a synthesis of qualitative evidence
  7. 833627
    “…One participant, who was in cohort 1, withdrew from the study due to adverse events, which included abdominal pain graded moderate or severe and associated with nausea after receiving the starting dose of 30 μg and one 60 μg dose. …”
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    Epitope-Specific Immunotherapy Targeting CD4-Positive T Cells in Celiac Disease: Safety, Pharmacokinetics, and Effects on Intestinal Histology and Plasma Cytokines with Escalating Dose Regimens of Nexvax2 in a Randomized, Double-Blind, Placebo-Controlled Phase 1 Study
  8. 833628
    Publicado 2018
    “…Eligible participants for first malaria episode and all retreatment episodes were adults and children aged 6 months and older with microscopically confirmed Plasmodium spp malaria (>0 to <200 000 parasites per μL of blood) and fever or history of fever in the previous 24 h. Individuals with severe or complicated malaria, an alanine aminotransferase concentration of more than twice the upper limit of normal, or a QTc greater than 450 ms were excluded. …”
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    Pyronaridine–artesunate or dihydroartemisinin–piperaquine versus current first-line therapies for repeated treatment of uncomplicated malaria: a randomised, multicentre, open-label, longitudinal, controlled, phase 3b/4 trial
  9. 833629
    “…Feasibility of the LPS approach would severely question the classic ‘single recruitment episode’ theory of follicular development. …”
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    Luteal phase anovulatory follicles result in the production of competent oocytes: intra-patient paired case-control study comparing follicular versus luteal phase stimulations in the same ovarian cycle
  10. 833630
    Publicado 2018
    “…We comparatively assessed the patterns and trends of healthy life expectancy (HALE), which quantifies the number of years of life expected to be lived in good health, and the complementary measure of disability-adjusted life-years (DALYs), a composite measure of disease burden capturing both premature mortality and prevalence and severity of ill health, for 359 diseases and injuries for 195 countries and territories over the past 28 years. …”
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    Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017
  11. 833631
    “…WHAT IS ALREADY KNOWN: An IUI has an important role in the treatment of severe male infertility, and is often used in same-sex female couples and single parents. …”
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    Clinical success of IUI cycles with donor sperm is not affected by total inseminated volume: a RCT
  12. 833632
    “…BACKGROUND: Previous studies have demonstrated that exposure to nickel nanoparticles (Nano-Ni) causes oxidative stress and severe, persistent lung inflammation, which are strongly associated with pulmonary toxicity. …”
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    Comparative mouse lung injury by nickel nanoparticles with differential surface modification
  13. 833633
    “…Landscape modification represents one of the most severe threats to biodiversity from local to global scales. …”
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    Guild-level responses of bats to habitat conversion in a lowland Amazonian rainforest: species composition and biodiversity
  14. 833634
    “…AUTHORS' CONCLUSIONS: We have high or moderate confidence in the evidence contributing to several of these review findings. Further research, especially in low‐ and middle‐income settings and with different cadres of healthcare providers, could strengthen the evidence for low‐ or very low‐confidence findings. …”
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    Perceptions and experiences of labour companionship: a qualitative evidence synthesis
  15. 833635
    “…Serum was collected at several time points after transplantation, and testosterone was measured. …”
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    Primary human testicular PDGFRα(+) cells are multipotent and can be differentiated into cells with Leydig cell characteristics in vitro
  16. 833636
    “…Due to the complexity and severity of this condition an MDT approach is recommended. …”
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    2. Two cases of anti-MDA5 positive dermatomyositis with rapidly progressive interstitial lung disease
  17. 833637
    por Mason, Alice, Williams, Emma
    Publicado 2019
    “…All patients presenting with ILD should have pulmonary function tests and imaging to assess severity of disease. CONFLICTS OF INTEREST: The authors have declared no conflicts of interest.…”
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    27. A new presentation of interstitial lung disease
  18. 833638
    “…CASE DESCRIPTION: A 40-year-old male was referred to acute medicine with 3 months of headache, fatigue, polyarthralgia, myalgia, night sweats, lymphadenopathy and otalgia. He reported a severe pharyngitis at symptom onset, 12 weeks earlier, for which he was given 20 days of phenoxymethylpenicillin by his GP. …”
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    20. A challenging diagnosis of adult-onset Still’s disease in the setting of raised anti-streptolysin O titres
  19. 833639
    por Alsaeid, Mohammed Awad
    Publicado 2019
    “…The therapeutic managements for CTS depend on the disease severity, varying from a conservative treatment to surgical interventions. …”
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    Dexamethasone versus Hyaluronidase as an Adjuvant to Local Anesthetics in the Ultrasound-guided Hydrodissection of the Median Nerve for the Treatment of Carpal Tunnel Syndrome Patients
  20. 833640
    “…Mean age, 68 ± 11 years; 58% Hispanic; 33% African American, 23% White, 1% Asian, 18% Unknown, 17% Other; 69% reported <$20000 annual income; 40% had not completed high school; 30% scored as moderately or severely frail; 83% were overweight or obese; and 33% reported a history of diabetes. 84% had uncontrolled high blood pressure; many participants were previously aware of their hypertension diagnosis. 3) A REDcap database was developed to store historical and prospective data. 4) Across frailty categories, there was a significant difference in utilization of non-meal (p = 0.0237) and meal services (p = 0.0127) and there was an inverse proportional relationship between the number of meal and non-meal visits, and frailty. …”
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    3310 A Community-Academic Partnership to Understand the Association Among Health Status and Senior Services Utilization to Improve Nutrition and Blood Pressure Control for Low Income Seniors Aging in Place
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