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  1. 1361
    “…Validation of these instruments provides reliable tools to measure disease severity and therapeutic effect in clinical studies. …”
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  2. 1362
    “…Disease severity was assessed by hand eczema severity index (HECSI) score and quality of life by dermatology life quality index (DLQI) questionnaire. …”
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  3. 1363
    “…OBJECTIVE: To examine how cigarette smoking, alcohol consumption, obesity, and physical activity are associated with the risk and severity of arthritis among adults living in Delaware. …”
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  4. 1364
    “…Dapsone (4,4'-diaminodiphenylsulfone, DDS), a potent anti-inflammatory agent, is widely used in the treatment of leprosy and several chronic inflammatory skin diseases. Dapsone therapy rarely results in development of dapsone hypersensitivity syndrome, which is characterized by fever, hepatitis, generalized exfoliative dermatitis, and lymphadenopathy. …”
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  5. 1365
    “…Given the growing body of evidence for the association of vitamin D with several neurodegenerative disorders and unavailability of any published study in the Middle East, the present study is aimed to determine the associations of circulating 25-hydroxyvitamin D (25OHD) levels with the severity of PD in an Iranian sample. …”
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  6. 1366
    “…“Bath salts” can also cause severe reversible dilated cardiomyopathy. Prior to diagnosis, other causes of cardiomyopathy including ischemic, infectious, familial, immunological, metabolic and cytotoxic may need to be ruled out; as was done in our patient.…”
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  7. 1367
    “…Schirmer's test was positive and salivary gland scintigraphy revealed severely decreased tracer uptakes in both parotid and submandibular glands. …”
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  8. 1368
    “…Thus, MC patients have an increased prevalence of several diseases, not only of autoimmune origin.…”
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  9. 1369
    “…Current World Health Organization (WHO) guidelines for severe pneumonia treatment of under-5 children recommend hospital referral. …”
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  10. 1370
    “…BACKGROUND: Alcohol withdrawal is a relatively common problem among chronic alcohol users, and its severity will determine the setting in which it will be more appropriate to take care of the patients. …”
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  11. 1371
  12. 1372
    “…BACKGROUND: In endemic areas, leptospirosis is more common and more severe in adults compared with children. Reasons to explain this discrepancy remain unclear and limited data focusing on adolescents are available. …”
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  13. 1373
  14. 1374
    “…OBJECTIVE: to compare the combined role of genetic variants loci associated with risk of knee or hip osteoarthritis (OA) in post-traumatic (PT) and non-traumatic (NT) cases of clinically severe OA leading to total joint replacement. METHODS: A total of 1590 controls, 2168 total knee replacement (TKR) cases (33.2% PT) and 1567 total hip replacement (THR) cases (8.7% PT) from 2 UK cohorts were genotyped for 12 variants previously reported to be reproducibly associated with risk of knee or hip OA. …”
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  15. 1375
  16. 1376
    “…Patients were classified into three severity groups: nonsevere, severe (those with at least one organ involvement), and deceased. …”
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  17. 1377
    “…BACKGROUND: Severe hypertension (SHT) (Blood Pressure, BP ≥ 180/110 mmHg) is associated with considerable morbidity and mortality, yet little is known about how it is managed. …”
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  18. 1378
  19. 1379
  20. 1380
    “…Although ganciclovir-induced encephalopathy has been described in several reports, a literature search revealed that ganciclovir concentrations in the blood or cerebrospinal fluid were previously measured in only 3 patients with encephalopathy. …”
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