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  1. 1821
    “…BACKGROUND: Excess visceral fat (VF) or high body mass index (BMI) is risk factors for severe COVID-19. The receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is expressed at higher levels in the VF than in the subcutaneous fat (SCF) of obese patients. …”
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    Visceral fat is associated to the severity of COVID-19
  2. 1822
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    Oral tacrolimus for severe recalcitrant eosinophilic cellulitis
  3. 1823
    “…Hypercalcemic crisis is a severe but rare complication of primary hyperparathyroidism (PHPT), and data on denosumab treatment of patients with this disease is still very limited. …”
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    Denosumab for management of severe hypercalcemia in primary hyperparathyroidism
  4. 1824
    “…Together, key genes unraveled by genetic profiling may provide targets for precisely early risk diagnosis and prophylactic design to relieve severe COVID-19. The confounding epigenetic mechanisms may be key to understanding the clinical broadness of COVID-19 illness.…”
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    Immunogenetic Association Underlying Severe COVID-19
  5. 1825
    “…AIM: Early diagnosis and treatment are crucial for the survival of severe Coronavirus Disease 2019 (COVID-19) patients, but data with regard to risk factors for disease progression from milder COVID-19 to severe COVID-19 remain scarce. …”
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    Predictive factors of progression to severe COVID-19
  6. 1826
    “…BACKGROUND: Approximately 6% of children hospitalized with severe falciparum malaria in Africa are also bacteremic. …”
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    Concomitant Bacteremia in Adults With Severe Falciparum Malaria
  7. 1827
    por Fainardi, Valentina, Saglani, Sejal
    Publicado 2020
    “…These children are described as having “difficult-to-treat asthma” while children with persistent symptoms despite above-mentioned factors having been addressed are described as having “severe therapy-resistant asthma”. In this review, we will describe the 6-step approach to the diagnosis and management of a child with problematic severe asthma adopted by The Royal Brompton Hospital (London, UK). …”
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    An approach to the management of children with problematic severe asthma
  8. 1828
    “…This case supports the use of hemodialysis for adult patients who meet the criteria of severe ethanol toxicity requiring critical care resources and having evidence of organ toxicity to 1 or more organ.…”
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    Acute Hemodialysis for Treatment of Severe Ethanol Intoxication
  9. 1829
    “…Within this context, during the last years several molecular effectors and signalling pathways have emerged as suitable targets for biological therapies of severe asthma, refractory to standard treatments. …”
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    Molecular Targets for Biological Therapies of Severe Asthma
  10. 1830
    “…Only the SIC showed the severity of the cook’s bronchial asthma.…”
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    Severe bronchial reaction to provocation with fish and crustaceans
  11. 1831
    “…This study addresses a gap in current research and holds important implications for helping providers meet government mandates and enhance care plan participation by residents with severe dementia and other communication challenges.…”
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    Supporting Persons With Severe Dementia in Communicating Their Preferences
  12. 1832
    por Kuo, Yin-Wei, Howard, Jonathon
    Publicado 2020
    “…Microtubule-severing enzymes – katanin, spastin, fidgetin – are related AAA-ATPases that cut microtubules into shorter filaments. …”
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    Cutting, Amplifying, and Aligning Microtubules with Severing Enzymes
  13. 1833
    “…This is the first case of acquired severe neutropenia in the context of COVID‐19 reported to date. …”
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    Can COVID‐19 cause severe neutropenia?
  14. 1834
    “…BACKGROUND: The coronavirus-19-disease (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread to >200 countries and surpassed 7 million cases. …”
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    519. Immune responses and COVID-19 severity
  15. 1835
    “…BACKGROUND: Although provider-derived surgical complication severity grading systems exist, little is known about the patient perspective. …”
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    Severity of Postoperative Complications From the Perspective of the Patient
  16. 1836
    “…OBJECTIVES: To determine the association between comorbidities and the severity of the disease among COVID-19 patients. METHODS: We searched the Cochrane, Medline, Trip, and EMBASE databases from 2019. …”
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    Comorbidities and severity of coronavirus disease 2019 patients
  17. 1837
    por Le, Kien, Nguyen, My
    Publicado 2021
    “…The alarming levels of spread and severity of COVID-19 have dominated global attention. …”
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    The psychological burden of the COVID-19 pandemic severity
  18. 1838
    “…BACKGROUND: Severe asthma is a subtype of asthma that can be hard to control, resulting in an exceptional impact on an individual's quality of life. …”
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    Perspectives on decisions for treatment and care in severe asthma
  19. 1839
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    Cutaneous manifestations of severe systemic disease in children
  20. 1840
    por Wilson, Clare
    Publicado 2020
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    Ventilators may not be best for severe covid-19
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