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  1. 1841
  2. 1842
  3. 1843
    “…BACKGROUND: Severe acute respiratory syndrome caused by novel coronavirus 2 (SARS-CoV-2) emerged in Wuhan (China) in December 2019. …”
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  4. 1844
    “…However, junctophilin-2 cluster density was considerably higher (0.12 ± 0.02 μm(−3) vs. 0.05 ± 0.01 μm(−3), n = 9/10, p < 0.001), approaching values of AVSD (0.13 ± 0.05 μm(−3), n = 56), and the measure of intact EC coupling junctions showed a distinct increase (20.2 ± 5.0% vs. 6.8 ± 2.2%, p < 0.001). Severe t-system loss and remodeling to t-sheets can occur in acute HF in young children, resembling the structural changes of chronically failing adult hearts. …”
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  5. 1845
  6. 1846
    “…Methods: In this prospective cross-sectional study, 172 eyes of 172 subjects, the severity degree of myopia was categorized into mild, moderate, severe, and extreme myopia. …”
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  7. 1847
    “…Coronavirus disease 2019 (COVID-19) is a pandemic viral pneumonia caused by severe acute respiratory syndrome coronavirus (SARS-CoV-2). …”
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  8. 1848
  9. 1849
    “…The COVID-19 pandemic in 2020 is one of the worst catastrophic events in human history. Several non-specific antiviral drugs have been tried to defeat the SARS-CoV-2, with mixed results. …”
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  10. 1850
    “…RESULTS AND CONCLUSION: We present a case that despite eventual relapse, made a remarkable functional recovery after bone marrow transplantation which may justify bone marrow transplantation in severe cases.…”
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  11. 1851
    “…A small proportion of individuals will go on to develop a more severe respiratory illness which may be complicated by acute respiratory distress syndrome. …”
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  12. 1852
    “…Some patients have a mild case and are able to function nearly on a par with healthy individuals, while others are moderately ill and still others are severely, or even, very severely ill. The cohort of moderately to very severely ill is often housebound or bedbound, has lost employment or career, and has engaged in a long, and often futile, search for treatment and relief. …”
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  13. 1853
    “…Severe Mycolicibacter kumamotonensis-pulmonary disease was diagnosed in a 68-year-old immunocompetent woman in Greece; the disease was initially treated as tuberculosis. …”
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  14. 1854
    “…On the basis of this background, we tested the hypothesis that anxiety could affect severe asthma outcomes in asthmatic adolescents. Therefore, a longitudinal real-world study included 40 consecutive adolescents (22 males, 18 females, mean age 14.18 ± 1.97 years) with severe asthma and visited for the first time at a third-level pediatric clinic. …”
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  15. 1855
  16. 1856
    “…Traumatic intrusion is considered one of the most severe luxation injuries to the permanent dentition. …”
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  17. 1857
    “…Drug hypersensitivity has a myriad of manifestations, which ranges from the mild maculopapular exanthema to the severe Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and drug reaction with eosinophilia and systemic symptoms/drug-induced hypersensitivity syndrome (DRESS/DIHS). …”
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  18. 1858
  19. 1859
    “…Plasma creatine kinase isoenzyme (CKMB) levels (P=0.01) were higher in the severe group than in the nonsevere group, and there were more deaths in the severe group than in the nonsevere group (6 (15%) vs. 3 (2.30%); P=0.05). …”
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  20. 1860
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