A universal fluorescence polarization high throughput screening assay to target the SAM-binding sites of SARS-CoV-2 and other viral methyltransferases

por Samrat, Subodh Kumar, Bashir, Qamar, Zhang, Ran, Huang, Yiding, Liu, Yuchen, Wu, Xiangmeng, Brown, Tyler, Wang, Wei, Zheng, Y. George, Zhang, Qing-Yu, Chen, Yin, Li, Zhong, Li, Hongmin
Publicado 2023

Age and geographic disparities in acute ischaemic stroke prehospital delays in China: a cross-sectional study using national stroke registry data

por Yuan, Jing, Lu, Z. Kevin, Xiong, Xiaomo, Li, Minghui, Liu, Yang, Wang, Long-De, Liu, Renyu, Zhao, Jing
Publicado 2023

Sputum pathogen spectrum and clinical outcomes of upper respiratory tract infection in bronchiectasis exacerbation: a prospective cohort study

por Huang, Yan, Chen, Chun-lan, Cen, Lai-jian, Li, Hui-min, Lin, Zhen-hong, Zhu, Si-yu, Duan, Chong-yang, Zhang, Ri-lan, Pan, Cui-xia, Zhang, Xiao-fen, Zhang, Xiao-xian, He, Zhen-feng, Shi, Ming-xin, Zhong, Nan-shan, Guan, Wei-jie
Publicado 2023

Characterizing the cellular and molecular variabilities of peripheral immune cells in healthy recipients of BBIBP-CorV inactivated SARS-CoV-2 vaccine by single-cell RNA sequencing

por Tong, Renyang, Luo, Lingjie, Zhao, Yichao, Sun, Mingze, Li, Ronghong, Zhong, Jianmei, Chen, Yifan, Hu, Liuhua, Li, Zheng, Shi, Jianfeng, Lyu, Yuyan, Hu, Li, Guo, Xiao, Liu, Qi, Shuang, Tian, Zhang, Chenjie, Yuan, Ancai, Sun, Lingyue, Zhang, Zheng, Qian, Kun, Chen, Lei, Lin, Wei, Chen, Alex F., Wang, Feng, Pu, Jun
Publicado 2023

Higher glucose fluctuation is associated with a higher risk of cardiovascular disease: Insights from pooled results among patients with diabetes

por Li, Feng, Zhang, Lei, Shen, Yun, Liu, Huan‐Huan, Zhang, Zhen‐Ye, Hu, Gang, Wang, Ru‐Xing
Publicado 2023

FGFR2 mutations promote endometrial cancer progression through dual engagement of EGFR and Notch signalling pathways

por Dixit, Garima, Gonzalez‐Bosquet, Jesus, Skurski, Joseph, Devor, Eric J., Dickerson, Erin B., Nothnick, Warren B., Issuree, Priya D., Leslie, Kimberly K., Maretzky, Thorsten
Publicado 2023

Orthogonal dual reporter-based gain-of-signal assay for probing SARS-CoV-2 3CL protease activity in living cells: inhibitor identification and mutation investigation

por Bei, Zhu-Chun, Yu, Huanhuan, Wang, Hong, Li, Qingyun, Wang, Baogang, Zhang, Dongna, Xu, Likun, Zhao, Liangliang, Dong, Shuwei, Song, Yabin
Publicado 2023

Genetic variants influenced the risk of bleeding and pharmacodynamics of rivaroxaban in patients with nonvalvular atrial fibrillation: A multicentre prospective cohort study

por Xiang, Qian, Wang, Zhe, Mu, Guangyan, Xie, Qiufen, Liu, Zhiyan, Zhou, Shuang, Zhang, Hanxu, Wang, Zining, Jiang, Jie, Hu, Kun, Zhang, Yatong, Zhao, Zinan, Yuan, Dongdong, Guo, Liping, Wu, Tingting, Zhang, Jinhua, Wang, Na, Xiang, Jing, Gu, Zhichun, Sun, Jianjun, Cui, Yimin
Publicado 2023

MERS-CoV seroconversion amongst Malaysian Hajj pilgrims returning from the Middle East, 2016–2018: results from the MERCURIAL multiyear prospective cohort study

por Johari, Jefree, Hontz, Robert D., Pike, Brian L., Husain, Tupur, Rusli, Norhayati, Mohd-Zain, Rozainanee, Tiong, Vunjia, Lee, Hai-Yen, Teoh, Boon-Teong, Sam, Sing-Sin, Khor, Chee-Sieng, Loong, Shih-Keng, Abd-Jamil, Juraina, Nor'e, Siti-Sarah, Yahaya, Hasmawati, Che-Kamaruddin, Naim, Garcia-Rivera, Jose A., AbuBakar, Sazaly
Publicado 2023

Peripheral blood mononuclear cell mitochondrial dysfunction in acute alcohol‐associated hepatitis

por Bellar, Annette, Welch, Nicole, Dasarathy, Jaividhya, Attaway, Amy, Musich, Ryan, Kumar, Avinash, Sekar, Jinendiran, Mishra, Saurabh, Sandlers, Yana, Streem, David, Nagy, Laura E, Dasarathy, Srinivasan
Publicado 2023

PLA2R1 Inhibits Differentiated Thyroid Cancer Proliferation and Migration via the FN1-Mediated ITGB1/FAK Axis

por Zheng, Hui, Zhang, Mengyu, Gao, Dingwei, Zhang, Xiaoying, Cai, Haidong, Cui, Zhijun, Gao, Yang, Lv, Zhongwei
Publicado 2023

Transcriptomic signature defines two subtypes of locally advanced PCa with distinct neoadjuvant therapy benefits

por Zhu, Yinjie, Fan, Liancheng, Zhu, Hanjing, Gong, Yiming, Chi, Chenfei, Wang, Yanqing, Pan, Jiahua, Dong, Baijun, Xue, Wei
Publicado 2023

HCFC1 variants in the proteolysis domain are associated with X‐linked idiopathic partial epilepsy: Exploring the underlying mechanism

por He, Na, Guan, Bao‐Zhu, Wang, Jie, Liu, Han‐Kui, Mao, Yong, Liu, Zhi‐Gang, Yin, Fei, Peng, Jing, Xiao, Bo, Tang, Bei‐sha, Zhou, Dong, Huang, Guang, Dai, Qi‐Lin, Zeng, Ying, Han, Hong, Zhai, Qiong‐Xiang, Li, Bin, Tang, Bin, Li, Wen‐Bin, Song, Wang, Liu, Liu, Shi, Yi‐Wu, Li, Bing‐Mei, Su, Tao, Zhou, Peng, Liu, Xiao‐Rong, Guo, Li‐Wu, Yi, Yong‐Hong, Liao, Wei‐Ping
Publicado 2023

COVID 19 and one health: potential role of human and animals in SARS-COV-2 life cycle

por Cupertino, Marli do Carmo, Freitas, Ana Nery Dias, Meira, Gabriela Silva Barbosa, Silva, Pedro Arthur Machado da, Pires, Sarah de Souza, Cosendey, Tamires de Abreu, Fernandes, Tapharell Miranda, Mayers, Nicholas Alfred Joseph, Siqueira-Batista, Rodrigo
Publicado 2023

Predictors of mortality from extended-spectrum beta-lactamase-producing Enterobacteriaceae bacteremia

por Namikawa, Hiroki, Imoto, Waki, Yamada, Koichi, Tochino, Yoshihiro, Kaneko, Yukihiro, Kakeya, Hiroshi, Shuto, Taichi
Publicado 2023

Adjuvant TACE may not improve recurrence-free or overall survival in HCC patients with low risk of recurrence after hepatectomy

por Feng, Long-Hai, Zhu, Yu-Yao, Zhou, Jia-Min, Wang, Miao, Xu, Wei-Qi, Zhang, Ti, Mao, An-Rong, Cong, Wen-Ming, Dong, Hui, Wang, Lu
Publicado 2023

PD1(hi) CD200(hi) CD4(+) exhausted T cell increase immunotherapy resistance and tumour progression by promoting epithelial–mesenchymal transition in bladder cancer

por Wu, Chun, Duan, Lianhui, Li, Hongmu, Liu, Xuefei, Cai, Taonong, Yang, Yang, Yin, Yuting, Chang, Wuguang, Zhong, Leqi, Zhang, Lin, Cheng, Yixin, Qin, Haide, Wen, Zhesheng, Wang, Huiyun, Mai, Shijuan
Publicado 2023

Smad3‐mediated lncRNA HSALR1 enhances the non‐classic signalling pathway of TGF‐β1 in human bronchial fibroblasts by binding to HSP90AB1

por Yi, Erkang, Lin, Biting, Zhang, Yi, Wang, Xiaoyu, Zhang, Jiahuan, Liu, Yu, Jin, Jing, Hong, Wei, Lin, Zhiwei, Cao, Weitao, Mei, Xinyue, Bai, Ge, Bing Li, Bing, Zhou, Yumin, Ran, Pixin
Publicado 2023

Integrated metabolic and genetic analysis reveals distinct features of human differentiated thyroid cancer

por Cararo Lopes, Eduardo, Sawant, Akshada, Moore, Dirk, Ke, Hua, Shi, Fuqian, Laddha, Saurabh, Chen, Ying, Sharma, Anchal, Naumann, Jake, Guo, Jessie Yanxiang, Gomez, Maria, Ibrahim, Maria, Smith, Tracey L., Riedlinger, Gregory M., Lattime, Edmund C., Trooskin, Stanley, Ganesan, Shridar, Su, Xiaoyang, Pasqualini, Renata, Arap, Wadih, De, Subhajyoti, Chan, Chang S., White, Eileen
Publicado 2023

Correlation of ACR and TcPO2 in diabetic kidney disease patients: A pilot study

por Sun, Jin, Huang, Yang, Li, Lanhua, Hu, Hao, Liu, Yuanyuan, Zhang, Xuelian, Zhang, Hao, Pan, Binbin
Publicado 2023