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221por Nie, Jing-Jing, Pian, Ya-Ya, Hu, Ji-Hong, Fan, Guo-Qing, Zeng, Lv-Tao, Ouyang, Qiu-Geng, Gao, Zhen-Xiang, Liu, Zhen, Wang, Chen-Chen, Liu, Qian, Cai, Jian-Ping“…BACKGROUND: Shigella flexneri (S. flexneri) is a major pathogen causing acute intestinal infection, but the systematic oxidative damage incurred during the course of infection has not been investigated. …”
Publicado 2021
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222por Chen, Poyin, Russo, Brian C., Duncan-Lowey, Jeffrey K., Bitar, Natasha, Egger, Keith T., Goldberg, Marcia B.Enlace del recurso
Publicado 2021
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223“…A novel nanomaterial Bacitracin-Ag Nanoclusters (Bacitracin-AgNCs) was formed to achieve a better antibacterial effect on Shigella flexneri which poses a serious threat to human health. …”
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224por Skovajsová, Eva, Colonna, Bianca, Prosseda, Gianni, Sellin, Mikael E, Di Martino, Maria LetiziaEnlace del recurso
Publicado 2022
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225“…Shigella flexneri is a facultative intracellular pathogen that causes bacillary dysentery in humans. …”
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226por Meron-Sudai, Shiri, Asato, Valeria, Adler, Amos, Bialik, Anya, Goren, Sophy, Ariel-Cohen, Ortal, Reizis, Arava, Mulard, Laurence A., Phalipon, Armelle, Cohen, Dani“…SF2a-TT15, a synthetic carbohydrate-based conjugate vaccine candidate against Shigella flexneri 2a (SF2a) was found safe and strongly immunogenic in adult volunteers. …”
Publicado 2023
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227“…This work aimed to develop vaccine candidates against the Shigella flexneri (S. flexneri) 2b serotype using the BGCs approach. …”
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228por Deane, Janet E., Cordes, Frank S., Roversi, Pietro, Johnson, Steven, Kenjale, Roma, Picking, William D., Picking, Wendy L., Lea, Susan M., Blocker, Ariel“…A monodisperse truncation mutant of MxiH, the subunit of the needle from the Shigella flexneri type III secretion system (TTSS), has been overexpressed and purified. …”
Publicado 2006
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229Publicado 1995“…To determine the role of humoral mucosal immune response in protection against shigellosis, we have obtained a monoclonal dimeric immunoglobulin A (IgA) antibody specific for Shigella flexneri serotype 5a lipopolysaccharide (mIgA) and used a murine pulmonary infection model that mimics the lesions occurring in natural intestinal infection. …”
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230“…BACKGROUND: In our earlier studies 34 kDa outer membrane protein (OMP) of Shigella flexneri 2a has been identified as an efficient immunostimulant. …”
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231por Dienemann, Christian, Bøggild, Andreas, Winther, Kristoffer S., Gerdes, Kenn, Brodersen, Ditlev E.“…Here, we describe the crystal structure of the intact Shigella flexneri VapBC TA complex, determined to 2.7 Å resolution. …”
Publicado 2011
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232por Mirnejad, Reza, Vahdati, Ali Reza, Rashidiani, Jamal, Erfani, Mohammad, Piranfar, Vahhab“…OBJECTIVES: This study evaluates the protective effect of Lactobacillus casei cell-free culture supernatants (CFCS) against multiple drug resistance (MDR) clinical samples of Shigella sonnei and Shigella flexneri in vitro. MATERIALS AND METHODS: S. sonnei and S .flexneri was identified by common microbiological and serological methods. …”
Publicado 2013
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233por Jarząb, Anna, Witkowska, Danuta, Ziomek, Edmund, Dąbrowska, Anna, Szewczuk, Zbigniew, Gamian, Andrzej“…Shigella flexneri 3a is one of the five major strains of the Shigella genus responsible for dysentery, especially among children, in regions of high poverty and poor sanitation. …”
Publicado 2013
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235“…Shigella flexneri is a human pathogen that triggers its own entry into intestinal cells and escapes primary vacuoles to gain access to the cytosolic compartment. …”
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236por Ulissi, Ulisse, Fabbretti, Attilio, Sette, Marco, Giuliodori, Anna Maria, Spurio, RobertoEnlace del recurso
Publicado 2014
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237por Scribano, Daniela, Damico, Rosanna, Ambrosi, Cecilia, Superti, Fabiana, Marazzato, Massimiliano, Conte, Maria Pia, Longhi, Catia, Palamara, Anna Teresa, Zagaglia, Carlo, Nicoletti, Mauro“…Shigella flexneri is an intracellular pathogen that deploys an arsenal of virulence factors promoting host cell invasion, intracellular multiplication and intra- and inter-cellular dissemination. …”
Publicado 2016
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238por Piro, Anthony S., Hernandez, Dulcemaria, Luoma, Sarah, Feeley, Eric M., Finethy, Ryan, Yirga, Azeb, Frickel, Eva M., Lesser, Cammie F., Coers, Jörn“…Here, we demonstrate that human GBP1 is unique among the seven human GBP paralogs in its ability to associate with at least two cytosolic Gram-negative bacteria, Burkholderia thailandensis and Shigella flexneri. Rough lipopolysaccharide (LPS) mutants of S. flexneri colocalize with GBP1 less frequently than wild-type S. flexneri does, suggesting that host recognition of O antigen promotes GBP1 targeting to Gram-negative bacteria. …”
Publicado 2017
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239por Fan, Wenting, Qian, Huimin, Shang, Wenkang, Ying, Chen, Zhang, Xuedi, Cheng, Song, Gu, Bing, Ma, Ping“…However, there is no analysis of related genes in Jiangsu Province of China so far. Shigella flexneri was collected from 13 cities of Jiangsu Province through the provincial Centers for Disease Control (CDC) for analysis of distribution of major virulence genes (ipaH, ipaBCD, ial, virF, virB, sigA, set1A, sepA, sat, pic, set1B and sen) detected by PCR technology. …”
Publicado 2017
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240por Guglielmino, Christine J. D., Kakkanat, Asha, Forde, Brian M., Rubenach, Sally, Merone, Lea, Stafford, Russell, Graham, Rikki M. A., Beatson, Scott A., Jennison, Amy V.“…All data were collected as part of routine public health surveillance, and strains were whole-genome sequenced for further molecular characterisation. 108 patients with an endemic regional Shigella flexneri strain were identified between 2016 and 2019. …”
Publicado 2020
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