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281por Mitchell, Holly D., Mikhail, Amy F. W., Painset, Anaïs, Dallman, Timothy J., Jenkins, Claire, Thomson, Nicholas R., Field, Nigel, Hughes, Gwenda“…We investigated whether WGS can distinguish between clusters representing sexual transmission in MSM and clusters representing community (non-sexual) transmission to inform infection control. WGS data for Shigella flexneri from August 2015 to July 2017 were aggregated into single linkage clusters based on SNP typing using a range of SNP distances (the standard for Shigella surveillance at PHE is 10 SNPs). …”
Publicado 2019
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282“…Outer membrane protein A (OmpA) of Shigella flexneri 2a has been demonstrated to induce the production of IgG and IgA in vivo following immunization of mice through intranasal route, but the direct involvement of B cells in OmpA-mediated immune regulation was not determined. …”
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283“…Shigella flexneri (S. flexneri), a leading cause of bacillary dysentery, is a major public health concern particularly affecting children in developing nations. …”
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284por Toapanta, Franklin R., Hu, Jingping, Meron-Sudai, Shiri, Mulard, Laurence A., Phalipon, Armelle, Cohen, Dani, Sztein, Marcelo B.Enlace del recurso
Publicado 2023
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287por Keller, Charlotte, Mellouk, Nora, Danckaert, Anne, Simeone, Roxane, Brosch, Roland, Enninga, Jost, Bobard, Alexandre“…Shigella flexneri are pathogenic bacteria that invade host cells entering into an endocytic vacuole. …”
Publicado 2013
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288“…The annual risks of infection due to E. coli and Shigella flexneri for most schools was high, with maximum values of 89.11 and 83.75%, respectively. …”
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289por Yuni Nur Hidayati, Dwi, Rully, Septha, Amalia, Aisyah, Larissa Widyani, Elsa, Indraswari, Genitri, Prasetya, Adrian, Soraya, Merika, Winarsih, Sri, Reto Prawiro, Sumarno“…The second group was given AMV and infected with Shigella flexneri. The third group was immunized with AMV before being exposed to Shigella flexneri. …”
Publicado 2022
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290por Webale, Mark Kilongosi, Wanjala, Christine, Guyah, Bernard, Shaviya, Nathan, Munyekenye, Godwil O., Nyanga, Peter Lokamar, Marwa, Immaculate Nyaseba, Kagoiyo, Sammy, Wangai, Laura Nyawira, Webale, Sella K., Kamau, Kenny, Kitungulu, Nicholas“…Shigella sero-grouping revealed that 0.5%, 0.3%, 1.9%, and 0.5% were infected with Shigella boydii, Shigella dysentriae, Shigella flexneri and Shigella sonnei pure isolates. Shigella species and E. coli co-infection was detected in 2.4% of the children, specifically, 1.1% for EAEC/Shigella boydii, 0.5% for EAEC/Shigella dysentriae and 0.3% in each case of EAEC/Shigella sonnei, EPEC/Shigella flexneri and ETEC/Shigella flexneri co-infections. …”
Publicado 2020
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291por Fukazawa, Atsuko, Alonso, Carmen, Kurachi, Kiyotaka, Gupta, Sonal, Lesser, Cammie F., McCormick, Beth Ann, Reinecker, Hans-Christian“…Shigella flexneri has evolved the ability to modify host cell function with intracellular active effectors to overcome the intestinal barrier. …”
Publicado 2008
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292por Tinevez, Jean-Yves, Arena, Ellen T, Anderson, Mark C, Nigro, Giulia, Injarabian, Louise, André, Antonin C, Ferrari, Mariana, Campbell-Valois, François-Xavier, Devin, Anne, Shorte, Spencer L, Sansonetti, Philippe J, Marteyn, Benoit S“…Pathogenic enterobacteria face various oxygen (O(2)) levels during intestinal colonization from the O(2)-deprived lumen to oxygenated tissues. Using Shigella flexneri as a model, we had previously demonstrated that epithelium invasion is promoted by O(2) in a Type III secretion system (T3SS)-dependent manner(1). …”
Publicado 2019
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293“…The K-B method was applied for the determination of drug resistance of Shigella flexneri, and polymerase chain reaction amplification was used for class 1, 2 and 3 integrase genes. …”
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294“…Escherichia coli was the most frequently isolated followed by Salmonella species (serogroups B, D, E, C(1), and NG), Bacillus cereus, and Shigella flexneri. Wide varieties of bacteria of medical relevance were also identified. …”
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295por Liu, Yanyan, Shen, Weihua, Sun, Yating, Lv, Na, Sun, Kaili, Hu, Lifen, Ye, Ying, Gao, Yufeng, Li, Jiabin“…Shigella flexneri strains harboring specific VRGs were associated with antimicrobial resistance. …”
Publicado 2020
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296por Galmbacher, Katharina, Heisig, Martin, Hotz, Christian, Wischhusen, Joerg, Galmiche, Antoine, Bergmann, Birgit, Gentschev, Ivaylo, Goebel, Werner, Rapp, Ulf R., Fensterle, Joachim“…Quantitative analysis of bacterial tumor targeting demonstrated that attenuated, invasive Shigella flexneri primarily infected TAMs after systemic administration. …”
Publicado 2010
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297por He, Fan, Han, Ke, Liu, Lunguang, Sun, Wei, Zhang, Lijie, Zhu, Baoping, Ma, Huilai“…Rectal swabs from 5 of 6 case-students and water from Well A yielded Shigella flexneri 2b. CONCLUSIONS: This shigellosis outbreak was caused by drinking untreated water from a well polluted by Shigella flexneri 2b.…”
Publicado 2012
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298por Shahsavan, Shadi, Nobakht, Maliheh, Rastegar-Lari, Abdolaziz, Owlia, Parviz, Bakhshi, Bita“…RESULTS: We found 14 Shigella sonnei and 6 Shigella flexneri isolates. Results of MLST showed five sequence types (ST) (145, 152, 241, 245, 1502) and BURST analysis revealed the largest number of single locus variant (SLV) and highest frequency (FREQ) for ST152. …”
Publicado 2016
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299por Torrez Lamberti, Mónica Florencia, López, Fabián Enrique, Valdez, Patricia, Bianchi, Ana, Barrionuevo Medina, Evangelina, Pescaretti, María de las Mercedes, Delgado, Mónica Alejandra“…The appearance of epidemic outbreaks, as happened during 2014, suggest that they may be related to the socio-economic poverty of NWA. Recently, Shigella flexneri 2 has become the highest NWA´s incidence infectious agent. …”
Publicado 2020
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300por Baker, Kate S, Mather, Alison E, McGregor, Hannah, Coupland, Paul, Langridge, Gemma C, Day, Martin, Deheer-Graham, Ana, Parkhill, Julian, Russell, Julie E, Thomson, Nicholas R“…We aimed to generate a high-quality reference genome of the historical Shigella flexneri isolate NCTC1 and to examine the isolate for resistance to antimicrobials. …”
Publicado 2014
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