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  1. 88361
    “…As retinitis pigmentosa is the only clinical sign in previously reported cases, this report broadens the spectrum of phenotypes associated with this condition.…”
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    A case of fatal Type I congenital disorders of glycosylation (CDG I) associated with low dehydrodolichol diphosphate synthase (DHDDS) activity
  2. 88362
    “…Loss of polarized distribution of the axonal protein tau is an early sign of Alzheimer’s disease (AD) and other neurodegenerative disorders. …”
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    Acetylated tau destabilizes the cytoskeleton in the axon initial segment and is mislocalized to the somatodendritic compartment
  3. 88363
    “…CD14+/CD68+ TAMs and CD3+ T lymphocytes were the major components of the inflammatory cell response but (DC-SIGN/CD11c+) DCs were also commonly noted when there was a significant TAM and T lymphocyte infiltrate. …”
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    Dendritic and mast cell involvement in the inflammatory response to primary malignant bone tumours
  4. 88364
    “…This article presents the statistical analysis plan for the main publication as approved and signed off by the Trial Steering Committee prior to the first data extraction for the Data Monitoring Committee meeting report. …”
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    A phase III, multi-centre, double-masked randomised controlled trial of adjunctive intraocular and peri-ocular steroid (triamcinolone acetonide) versus standard treatment in eyes undergoing vitreoretinal surgery for open globe trauma (ASCOT): statistical analysis plan
  5. 88365
    “…Wilcoxon matched-pairs signed-rank test was used to compare FGF23 before and after sodium bicarbonate. …”
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    Effect of oral sodium bicarbonate on fibroblast growth factor-23 in patients with chronic kidney disease: a pilot study
  6. 88366
    “…Most clinical features of our patient were consistent with those previous reported for UPD(14)mat cases, which include prenatal and postnatal growth retardation, neonatal hypotonia, feeding difficulty, intellectual disability, truncal obesity, small hands and feet, short stature, and mild facial dysmorphism, but our patient showed more severe intellectual disability and no sign of precocious puberty. SNP array analysis revealed a mixture of chromosome 14 maternal isodisomy with heterodisomy and a low level trisomy mosaicism of whole chromsome 14 in blood and hyperpigmented skin samples, whereas only UPD(14)mat was detected in normal skin sample. …”
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    Maternal uniparental disomy 14 and mosaic trisomy 14 in a Chinese boy with moderate to severe intellectual disability
  7. 88367
    “…Patients who have paid employment at the time of diagnosis, are on sick leave and are between 18–62 years old will be eligible to participate. After patients have signed the informed consent form and filled in the baseline questionnaire, they are randomly allocated to either the nurse-led, stepped-care, e-health intervention called Cancer@Work, or care as usual. …”
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    Cancer@Work — a nurse-led, stepped-care, e-health intervention to enhance the return to work of patients with cancer: study protocol for a randomized controlled trial
  8. 88368
    “…Consequently, options were not available for patients to indicate their preference for receiving their individual results when they signed pharmacogenetic informed consent. Differences in local requirements, clinical practice, and opinion regarding the ethical aspects of how to convey genetic results to patients are all potential barriers to returning individual BRCA results to patients. …”
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    Communicating BRCA research results to patients enrolled in international clinical trials: lessons learnt from the AGO-OVAR 16 study
  9. 88369
    “…This resulted in an estimated 16.5 % cost saving (Wilcoxon signed-rank test, p < 0.0001). The greatest savings were observed in administration costs (37.5 % less) and transportation costs (68.1 % less). …”
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    Cost savings of home bortezomib injection in patients with multiple myeloma treated by a combination care in Outpatient Hospital and Hospital care at Home
  10. 88370
    “…Abdominal tenderness developed in all the patients with severe AP, while lack of abdominal tenderness was a favourable sign for mortality. Importantly, lung injury at admission was associated with mortality. …”
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    Prospective, Multicentre, Nationwide Clinical Data from 600 Cases of Acute Pancreatitis
  11. 88371
    “…None of the patients at any of the three dose levels showed any sign of DLTs. The main adverse events were increased serum γ‐glutamyl transpeptidase, hyperglycemia, and increased serum total bilirubin; however, all the toxicities were mild. …”
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    Phase I trial of GBS‐01 for advanced pancreatic cancer refractory to gemcitabine
  12. 88372
    “…The translocation of NF-κB and phosphorylation of IκBα, NF-κB, p38, JNK, and ERK were significantly inhibited by H-RN. No sign of toxicity was observed. CONCLUSIONS: H-RN effectively attenuated keratitis in vivo and in vitro induced by LPS or poly(I:C) through blocking NF-κB and MAPK signaling pathways. …”
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    Inhibitory effect of a novel peptide, H-RN, on keratitis induced by LPS or poly(I:C) in vitro and in vivo via suppressing NF-κB and MAPK activation
  13. 88373
    “…All participants will sign a free and informed consent form before randomisation. …”
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    Randomised, prospective, medico-economic nationwide French study of islet transplantation in patients with severely unstable type 1 diabetes: the STABILOT study protocol
  14. 88374
    por Bigdeli, T B, Ripke, S, Peterson, R E, Trzaskowski, M, Bacanu, S-A, Abdellaoui, A, Andlauer, T F M, Beekman, A T F, Berger, K, Blackwood, D H R, Boomsma, D I, Breen, G, Buttenschøn, H N, Byrne, E M, Cichon, S, Clarke, T-K, Couvy-Duchesne, B, Craddock, N, de Geus, E J C, Degenhardt, F, Dunn, E C, Edwards, A C, Fanous, A H, Forstner, A J, Frank, J, Gill, M, Gordon, S D, Grabe, H J, Hamilton, S P, Hardiman, O, Hayward, C, Heath, A C, Henders, A K, Herms, S, Hickie, I B, Hoffmann, P, Homuth, G, Hottenga, J-J, Ising, M, Jansen, R, Kloiber, S, Knowles, J A, Lang, M, Li, Q S, Lucae, S, MacIntyre, D J, Madden, P A F, Martin, N G, McGrath, P J, McGuffin, P, McIntosh, A M, Medland, S E, Mehta, D, Middeldorp, C M, Milaneschi, Y, Montgomery, G W, Mors, O, Müller-Myhsok, B, Nauck, M, Nyholt, D R, Nöthen, M M, Owen, M J, Penninx, B W J H, Pergadia, M L, Perlis, R H, Peyrot, W J, Porteous, D J, Potash, J B, Rice, J P, Rietschel, M, Riley, B P, Rivera, M, Schoevers, R, Schulze, T G, Shi, J, Shyn, S I, Smit, J H, Smoller, J W, Streit, F, Strohmaier, J, Teumer, A, Treutlein, J, Van der Auwera, S, van Grootheest, G, van Hemert, A M, Völzke, H, Webb, B T, Weissman, M M, Wellmann, J, Willemsen, G, Witt, S H, Levinson, D F, Lewis, C M, Wray, N R, Flint, J, Sullivan, P F, Kendler, K S
    Publicado 2017
    “…Subsequent trans-ancestry meta-analyses combined SNP-level evidence of association. Sign tests and polygenic score profiling weakly support an overlap of SNP effects between East Asian and European populations. …”
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    Genetic effects influencing risk for major depressive disorder in China and Europe
  15. 88375
    “…Health literacy was measured by the Newest Vital Sign (NVS), and the physical and mental components of quality of life were evaluated by the Short Form Health Survey Version 2 (SF-12v2). …”
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    The relationship between health literacy and quality of life among frequent users of health care services: a cross-sectional study
  16. 88376
    “…Quantitative real-time polymerase chain reaction was performed for miRNA amplification, and 19 miRs were included in statistical analysis. Wilcoxon signed-rank tests were used to compare within-patient median relative quantification values pre- and post-LVAD placement. …”
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    Plasma Levels of MicroRNA-155 Are Upregulated with Long-Term Left Ventricular Assist Device Support
  17. 88377
    “…Of the 200 patients that participated, 39 (19.5%) patients signed consent to participate in a therapeutic clinical trial; 27 (13.5%) patients enrolled, resulting in a 7.5% increase from our baseline comparison of 6% clinical trial enrollment rate in black cancer patients (p < .001). …”
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    Video intervention increases participation of black breast cancer patients in therapeutic trials
  18. 88378
    “…The participants receive oral and written information about the project and sign a consent form before participation. They can, whenever they want, withdraw from the study, and all de-identified data will be safely stored on the research server at Diakonhjemmet Hospital. …”
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    A hospital-based observational cohort study exploring pain and biomarkers in patients with hand osteoarthritis in Norway: The Nor-Hand protocol
  19. 88379
    “…BACKGROUND: A classic sign of canine syringomyelia (SM) is scratching towards one shoulder. …”
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    MRI characteristics for “phantom” scratching in canine syringomyelia
  20. 88380
    “…Patients agreeing to participate will sign an informed consent form before entering the study. …”
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    Subclinical Propionibacterium acnes infection estimation in the intervertebral disc (SPInE-ID): protocol for a prospective cohort
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