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90821por Fu, Guochen, Shi, Yulin, Yan, Yongfu, Li, Yajie, Han, Jing, Li, Guosheng, Lin, Ruyi, Wang, Yuning, Fu, Zihan, Gong, Qingxin, Gan, Yuhang, Wei, Jiaxing, Wang, Junfang“…METHODS: A cross-sectional study was conducted from October 6, 2016 to December 31, 2016 in Hubei University of Science and Technology in China. After signing informed consent, college students completed a self-designed online questionnaire distributed via https://www.wjx.cn/ voluntarily, anonymously and confidentially. …”
Publicado 2018
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90822por Lynch, Elizabeth A, Ramanathan, Shanthi A, Middleton, Sandy, Bernhardt, Julie, Nilsson, Michael, Cadilhac, Dominique A“…Most researchers (n=54, 98%) reported that research translation was important, particularly in terms of generating research impact, but the most common sign of project completion reported by researchers (n=7, 100% preclinical; n=37, 77% clinical) was publication. …”
Publicado 2018
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90823por Chan, Stanley Kam Chung, Zhang, Dexing, Bögels, Susan M, Chan, Christian Shaunlyn, Lai, Kelly Yee Ching, Lo, Herman Hay Ming, Yip, Benjamin Hon Kei, Lau, Elsa Ngar Sze, Gao, Tiffany Ting, Wong, Samuel Yeung Shan“…Participants will be required to sign informed consent form from both parents and children. …”
Publicado 2018
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90824por Liu, Yin, Wang, Hai-Bo, Li, Xiang, Xiao, Jian-Yong, Wang, Ji-Xiang, Reilly, Kathleen H., Sun, Bo, Gao, Jing“…We will recruit subjects with SVGD scheduled to receive PCI, aged 18–80 years, with a history of previous coronary artery bypass graft (CABG) surgery more than 1 year ago, and willing to participate in the study and sign informed consent. The composite primary study endpoint is the incidence of MACEs after PCI for SVGD, including death from cardiac causes, non-fatal myocardial infarction, unplanned target lesion revascularization (TLR) and target vessel revascularization (TVR). …”
Publicado 2018
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90825por Piantoni, Lucas, Tello, Carlos A., Remondino, Rodrigo G., Bersusky, Ernesto S., Menéndez, Celica, Ponce, Corina, Quintana, Susana, Hekier, Felisa, Francheri Wilson, Ida A., Galaretto, Eduardo, Noël, Mariano A.“…MATERIAL AND METHOD: We assessed a total of 43 non-consecutive female patients (mean age at questionnaire, 13 years and 1 month and 10 years and 8 months to 14 years and 5 months; mean period of usage of brace, 1 year and 7 months), with adolescent idiopathic scoliosis (AIS), older than 10 years of age until skeletal maturity, with a Risser sign less than 3 and scoliosis between 20 and 45°, treated with thoracolumbosacral orthosis (TLSO) for a period longer than 6 months, and without other comorbidities or previous surgeries, were evaluated. …”
Publicado 2018
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90826por Ji, Taoyun, Yang, Zhao, Liu, Qingzhu, Liao, Jianxiang, Yin, Fei, Chen, Yanhui, Zou, Liping, Li, Baomin, Gao, Yuxing, Shu, Xiaomei, Huang, Shaoping, Gao, Feng, Liang, Jianmin, Lin, Su Fang, Peng, Jing, Song, Shiwei, Wang, Jing, Che, Chao, Sun, Wenxiu, Tian, Maoqiang, Yang, Lin, Hua, Yi, Hao, Yunpeng, Cai, Lixin, Li, Luming, Jiang, Yuwu“…Before enrollment, informed consent will be signed by the parents of the participants and the study researchers. …”
Publicado 2019
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90827por Wei, Hui, Wang, Wei, Alper, Hal S., Xu, Qi, Knoshaug, Eric P., Van Wychen, Stefanie, Lin, Chien-Yuan, Luo, Yonghua, Decker, Stephen R., Himmel, Michael E., Zhang, Min“…Cellulase co-expression in YL165-1 in culture media with a moderate C/N ratio of ∼4.5 unexpectedly resulted in a nearly two-fold reduction in cellular lipid accumulation compared to the parental control strain, a sign of cellular metabolic drain. Such metabolic drain was ameliorated when grown in media with a high C/N ratio of 59 having a higher glucose utilization rate that led to approximately twofold more cell mass and threefold more lipid production per liter culture compared to parental control strain, suggesting cross-talk between cellulase and lipid production, both of which involve the endoplasmic reticulum (ER). …”
Publicado 2019
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90828“…RESULTS: Although 39% (7/18) of participants interviewed signed up for MyChart, only 22% (4/18) of them became active users. …”
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90829por Regan, Jemma, Frison, Eric, Collin, Fidéline, Dawes, Piers, Hann, Mark, Himmelsbach, Ines, Hooper, Emma, Reeves, David, Simkin, Zoe, Thodi, Chryssoula, Yang, Fan, Leroi, Iracema“…Three hundred fifty four people with dementia and hearing or vision impairment (or both) and their companions will be randomly assigned to receive either “care as usual” or a multi-component sensory intervention including assessment and correction of hearing or vision impairments (or both), home-based (maximum 10 visits over 18 weeks), therapist-delivered sensory support (that is, adherence to devices; improving the sensory environment (that is, lighting), communication training, and sign-posting to other support agencies). Change from baseline to intervention end (18 weeks) and post-intervention (36 weeks) will be compared between the two arms in the following outcomes: quality of life (primary endpoint), sensory and cognitive functional ability, relationships, mental well-being, health resource utilisation and cost-effectiveness. …”
Publicado 2019
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90830por Sánchez-Trujillo, Luis, Jerjes-Sanchez, Carlos, Rodriguez, David, Panneflek, Jathniel, Ortiz-Ledesma, Claudia, Garcia-Rivas, Gerardo, Torre-Amione, Guillermo“…ETHICS AND DISSEMINATION: The following protocol was approved by IRB committees, and as a requirement, all patients need to sign an informed consent form before being subjected to any procedure prior to the initiation of the study. …”
Publicado 2019
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90831por Fukushima, Kazunori, Kawai-Kowase, Keiko, Yonemoto, Yukio, Fujiwara, Makoto, Sato, Hiroko, Sato, Mahito, Kubota, Takuo, Ozono, Keiichi, Tamura, Junich“…Clinically, hypophosphatasia can be categorized as perinatal, infantile, childhood, and adult forms, as well as odonto-hypophosphatasia, according to the age at first sign or dental manifestations. Adult hypophosphatasia typically presents in middle-aged patients who appear to be in good health in early adulthood and manifests as painful feet caused by recurrent, slow-healing stress fractures of the lower limb. …”
Publicado 2019
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90832“…Postoperative pain score ≥4 points was considered as a sign of failure this series at 3 months after surgery. …”
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90833por Wang, Si-qi, Ren, Fang-yuan, Wang, Jian-hua, Ren, Zhi-hao, Jin, Zhong-gao, Xu, Yu, Li, Zhen-hui, Ding, Qian-jiang, Zhong, Chao“…CTA shows a three-dimensional testicular vascular pedicle sign of a seminoma. A combination of CT and CTA can improve the diagnostic accuracy of an intra-abdominal undescended testis secondary seminoma.…”
Publicado 2019
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90834por Ahmad Nasrollahi, Saman, Sabet Nematzadeh, Maede, Samadi, Aniseh, Ayatollahi, Azin, Yadangi, Somayeh, Abels, Christoph, Firooz, Alireza“…Patients and methods: Twenty-two female volunteers (mean±standard deviation of age: 39.20±4.16 years) who fulfilled the eligibility criteria participated in this study after signing the informed consent. They were requested to apply the Januluma(®)cream every night for 8 weeks. …”
Publicado 2019
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90835por Hall, Leangelo, Frizzera, Luma Paiva, Coelho, Laura Fernandes, Carricondo, Pedro Carlos, Oyamada, Maria Kiyoko, Pimentel, Sergio Luis Gianotti, Abalem, Maria Fernanda“…Pairwise t-tests and the Wilcoxon signed-rank test were conducted to compare the outcome measures. …”
Publicado 2019
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90836por Egan, Michael F., Mukai, Yuki, Voss, Tiffini, Kost, James, Stone, Julie, Furtek, Christine, Mahoney, Erin, Cummings, Jeffrey L., Tariot, Pierre N., Aisen, Paul S., Vellas, Bruno, Lines, Christopher, Michelson, David“…Adverse events and relevant laboratory, vital sign, and ECG findings were assessed. RESULTS: Verubecestat 12 mg and 40 mg were associated with an increase in the percentage of participants reporting adverse events versus placebo (89 and 92% vs. 82%), although relatively few participants discontinued treatment due to adverse events (8 and 9% vs. 6%). …”
Publicado 2019
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90837por Matvienko-Sikar, Karen, Toomey, Elaine, Queally, Michelle, Flannery, Caragh, O Neill, Kate, Dinan, Ted G, Doherty, Edel, Harrington, Janas M, Hayes, Catherine, Heary, Caroline, Hennessy, Marita, Kelly, Colette, Mc Hugh, Sheena M, McSharry, Jenny, Stanton, Catherine, Heffernan, Tony, Byrne, Molly, Kearney, Patricia M“…The intervention will be delivered at the infant’s 2, 4, 6, 12 and 13 month vaccination visits and involves brief verbal infant feeding messages and additional resources, including a leaflet, magnet, infant bib and sign-posting to an information website. The implementation strategy encompasses a local opinion leader, HCP training delivered prior to intervention delivery, electronic delivery prompts and additional resources, including a training manual, poster and support from the research team. …”
Publicado 2019
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90838“…Statistical analyses were performed using paired t-tests and Wilcoxon matched-pairs signed-rank sum tests with Bonferroni correction after the Friedman test. …”
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90839por Yang, Fan, Wei, Qiushi, Chen, Xiaojun, Hong, Guoju, Chen, Zhenqiu, Chen, Yaolong, He, Wei“…CONCLUSIONS: A better clinic response was obtained after this treatment, especially in femoral heads before the appearance of a crescent sign. The fixation of the implanted iliac bone flap increases the clinical effect. …”
Publicado 2019
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90840por Kralik, Michal, Cvecka, Jan, Buzgo, Gabriel, Putala, Matus, Ukropcova, Barbara, Ukropec, Jozef, Killinger, Zdenko, Payer, Juraj, Kollarik, Boris, Bujdak, Peter, Raastad, Truls, Sedliak, Milan“…ETHICS AND DISSEMINATION: This trial is approved by Ethics Committee of the University Hospital in Bratislava, Slovakia, (ref. trial number: 127/2017) and all subjects will be fully informed on the rationale, risks and benefits of the study and sign the written informed consent prior to entering the study. …”
Publicado 2019
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