“…Our data uncovered a novel epigenetic mechanism by which SINEs regulate gene expression during puberty.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Inpp5f_v3 initiates from a CpG-rich repeat region adjoining two B1 elements, despite previous reports that SINEs are generally excluded from imprinted promoters. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Results in ongoing trials will help further define the role of SINEs in MM.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…\end{displaymath} The values of its angles, in their customary definition in terms of sines for $\alpha$ a nd $\beta$, are found to be: \begin{displaymath} \sin{2\alpha} =0.06 ^{+0.35} _{-0.42} \,\,\,\,\, \sin{2\beta} =0.75 \pm 0.09 \,\,\,\,\, \gamma =67 ^{+11} _{-12}\,^\circ. …”
Enlace del recurso
Enlace del recurso

“…Here we are addressing this question in the green anole (Anolis carolinensis) whose genome contains an extraordinary diversity of TEs (including non-LTR retrotransposons, SINEs, LTR-retrotransposons and DNA transposons). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The analyses of transposable elements suggested the contraction of short interspersed nuclear elements (SINEs) and the accumulation of young mariner DNA transposons in the analysed hipposiderids. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: CGGBP1 is a repetitive DNA-binding transcription regulator with target sites at CpG-rich sequences such as CGG repeats and Alu-SINEs and L1-LINEs. The role of CGGBP1 as a possible mediator of CpG methylation however remains unknown. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: In eukaryotes, RNA polymerase III (RNAP III) transcribes the genes for small RNAs like tRNAs, 5S rRNA, and several viral RNAs, and short interspersed repetitive elements (SINEs). The genes for these RNAs and SINEs have internal promoters that consist of two regions. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…RESULTS: Sequencing results of LALBA gene promoter region confirmed the presence of SINEs as monomorphic “within” and variable in size “among” the selected species. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In contrast, short interspersed elements (SINEs) are preferentially overrepresented in nucleosome-containing boundaries. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The two other classes of retroelements, SINEs (four families) and LINEs (at least 30 families), were observed to contribute 1,991 and ∼35,000 copies, respectively, or a combined ∼1% of the B73 nuclear genome. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here we use Alu elements, a family of primate-specific Short INterspersed Elements (SINEs), to construct a phylogeny of infraorder Lemuriformes. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Interesting highlights of our results include: 1) the baboon genome has the highest number of SS-MEs with a strong bias for SINEs, while the crab-eating macaque genome has a sustained extremely low transposition for all ME classes, suggesting the existence of a genome-wide mechanism suppressing ME transposition; 2) while SS-SINEs represent the dominant class in general, the orangutan genome stands out by having SS-LINEs as the dominant class; 3) the human genome stands out among the eight genomes by having the largest number of recent highly active ME subfamilies, suggesting a greater impact of ME transposition on its recent evolution; and 4) at least 33% of the SS-MEs locate to genic regions, including protein coding regions, presenting significant potentials for impacting gene function. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Four families and 19 subfamilies of LINE1s, two families and nine subfamilies of SINEs, and 12 ERV families were defined in rabbit based on sequence identity, structural organization, and phylogenetic tree. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Mammalian genomes are typically dominated by LINE retrotransposons and their associated SINEs, and germline mobilization is a challenge to genome integrity. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Two advanced methods of analysis/synthesis are given: "Sines Plus Transients Plus Noise" and "Spectrotemporal Reassignment" are covered. …”
Enlace del recurso
Enlace del recurso

“…Relative to that in plasma, eccDNA in placenta was larger and substantially more abundant in exons, untranslated regions, promoters, repetitive elements [short interspersed nuclear elements (SINEs)/Alu, SINEs/mammalian-wide interspersed repeats, long terminal repeats/endogenous retrovirus-like elements, and single recognition particle RNA], and transcription factor binding motifs. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We found that fenofibrate, and bezafibrate to a lesser extent, up-regulated probes mapped to retrotransposons: Short-Interspersed Elements (SINEs) and Long-Interspersed Elements (LINEs), in the PFC. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Moreover, we observe significant enrichment of SINEs in γH2AX sites in all treatments, indicating that SINEs may be a common barrier for replication polymerases. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Selective inhibitors of nuclear export (SINE) are emerging as a potentially efficacious therapeutic strategy for overcoming resistance to conventional chemotherapy for acute myeloid leukemia. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso