Materias dentro de su búsqueda.
Mostrando 121 - 140 Resultados de 145 Para Buscar '"Snatch"', tiempo de consulta: 0.84s Limitar resultados
  1. 121
    “…Translation of viral mRNAs by the host ribosome requires mRNA capping for recognition and binding, and the necessary mRNA caps are cleaved or “snatched” from host pre-mRNAs by the PA endonuclease. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Structural and Biochemical Basis for Development of Influenza Virus Inhibitors Targeting the PA Endonuclease
  2. 122
    “…Influenza polymerase uses short capped primers snatched from nascent Pol II transcripts to initiate transcription of viral mRNAs. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Capped RNA primer binding to influenza polymerase and implications for the mechanism of cap-binding inhibitors
  3. 123
    “…Here, we investigated the foraging success of wild common ravens, Corvus corax, experiencing high levels of kleptoparasitism from conspecifics when snatching food from the daily feedings of captive wild boars in a game park in the Austrian Alps. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Decision time modulates social foraging success in wild common ravens, Corvus corax
  4. 124
    “…Drug-crime correlation has been noted among consumption of cannabis with murder, inhalants with rape and opioids with snatching-related crimes. CONCLUSION: Substance use and criminal behavior are clearly interrelated. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Substance use and criminality among juveniles-under-enquiry in New Delhi
  5. 125
    “…The study shows that (i) the N-terminal region of RdRp (SRD-1) of both the viruses contain “cap-snatching” endonuclease domain and a 13 AA cap binding site at the C-terminal, essential for viral cap-dependent transcription similar to the members of Bunyaviridae family and (ii) P4 is the movement protein and may belong to ‘30 K superfamily’ of MPs.…”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Molecular characterization of emaraviruses associated with Pigeonpea sterility mosaic disease
  6. 126
    “…To transcribe these viral genome segments, the RdRp “snatches” capped RNA oligonucleotides from nascent host cell mRNAs and aligns these primers to the ultimate or penultimate nucleotide of the segments for the initiation of viral mRNA synthesis. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Initiation, Elongation, and Realignment during Influenza Virus mRNA Synthesis
  7. 127
    “…These neuroanatomical features are consistent with fast, downward snatching movements in the act of predation, such as are needed for piscivory.…”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Neuroanatomy of the spinosaurid Irritator challengeri (Dinosauria: Theropoda) indicates potential adaptations for piscivory
  8. 128
    “…Due to its crucial role in the cap-snatching mechanism required for initiation of viral RNA transcription, the endoN domain is an ideal antiviral drug target. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Virtual screening of phytochemicals from Indian medicinal plants against the endonuclease domain of SFTS virus L polymerase
  9. 129
    “…Transcription initiation takes place by a cap-snatching mechanism whereby the polymerase steals a cellular capped oligonucleotide and uses it as primer to copy the vRNP template. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Texto
    Genetic trans-Complementation Establishes a New Model for Influenza Virus RNA Transcription and Replication
  10. 130
    “…Their cooperation and stepwise activation include a process called cap-snatching, which is a crucial step in the IAV life cycle. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Structural and Thermodynamic Analysis of the Resistance Development to Pimodivir (VX-787), the Clinical Inhibitor of Cap Binding to PB2 Subunit of Influenza A Polymerase †
  11. 131
    “…The pivotal role played by the cap-snatching process in the life cycle of the virus and the highly conserved nature of the endonuclease domain make it a target of choice for the development of novel antiviral therapies. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Crystal structures of Lymphocytic choriomeningitis virus endonuclease domain complexed with diketo-acid ligands
  12. 132
    “…Bunyaviruses, like influenza viruses (IFVs), possess a cap-dependent endonuclease (CEN) that mediates the critical cap-snatching step of viral RNA transcription. We screened compounds from our CEN inhibitor (CENi) library and identified specific structural compounds that are 100 to 1,000 times more active in vitro than ribavirin against bunyaviruses, including Lassa virus, lymphocytic choriomeningitis virus (LCMV), and Junin virus. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Identification of cap-dependent endonuclease inhibitors with broad-spectrum activity against bunyaviruses
  13. 133
    “…The recent COVID-19 pandemic has been havoc that spread like wildfire, snatching the lives of many, attacking the mental health of many more, and leaving a major chunk with the constant fear of contracting this illness. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Behind the Frontline: A Review on the Impact of COVID-19 Pandemic on Healthcare Workers
  14. 134
    “…Background: The cap-snatching mechanism of influenza virus mRNA transcription is strongly suppressed by TG-1000, a prodrug rapidly metabolized into TG-0527, is a potent cap-dependent nucleic acid endonuclease inhibitor. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Safety, tolerability, and pharmacokinetics of TG-1000, a new molecular entity against influenza virus: first-in-human study
  15. 135
    “…Interference with the endonucleolytic “cap-snatching” reaction by the HTN virus RdRp endonuclease domain is a particularly appealing approach for drug discovery against this virus. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Insight into the Hantaan virus RNA-dependent RNA polymerase inhibition using in-silico approaches
  16. 136
    “…Metal cations created ferromagnetic exchange interactions by snatching free electrons in oxygen.…”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Structural, Optical, Electric and Magnetic Characteristics of (In(1−x)Gd(x))(2)O(3) Films for Optoelectronics
  17. 137
    “…In vitro transcription of recombinant RNPs generated in SFPQ/PSF-silenced cells indicated a 4–5-fold reduction in polyadenylation but no alteration in cap snatching. These results indicate that SFPQ/PSF is a host factor essential for influenza virus transcription that increases the efficiency of viral mRNA polyadenylation and open the possibility to develop new antivirals targeting the accumulation of primary transcripts, a very early step during infection.…”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    The Splicing Factor Proline-Glutamine Rich (SFPQ/PSF) Is Involved in Influenza Virus Transcription
  18. 138
    “…Their Gag-Pol amino-acid sequences also contain the features required for cap-snatching and RNA polymerase activity. However, some of these motifs and features are similar to those of LA viruses, which may explain that at least TdV-LBCbarr2 has a helper ability to maintain M killer viruses. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Genome Features of a New Double-Stranded RNA Helper Virus (LBCbarr) from Wine Torulaspora delbrueckii Killer Strains
  19. 139
    “…Similarly, the Gag-Pol amino-acid sequence of this virus contains all the features required for cap-snatching and RNA polymerase activity, as well as the expected regional variables previously found in other LA viruses. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Genome Organization of a New Double-Stranded RNA LA Helper Virus From Wine Torulaspora delbrueckii Killer Yeast as Compared With Its Saccharomyces Counterparts
  20. 140
    “…Initiation of viral mRNA synthesis requires a direct association of FluPol with the host RNA polymerase II (RNAP II), in particular the repetitive C-terminal domain (CTD) of the major RNAP II subunit, to enable “cap-snatching” whereby 5’-capped oligomers derived from nascent RNAP II transcripts are pirated to prime viral transcription. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Type B and type A influenza polymerases have evolved distinct binding interfaces to recruit the RNA polymerase II CTD
Herramientas de búsqueda: RSS