Mostrando 201 - 220 Resultados de 703 Para Buscar '"Socing"', tiempo de consulta: 0.11s Limitar resultados
  1. 201
    “…STIM2.1 knockdown increases SOCE in naive CD4(+) T cells, whereas knockdown of STIM2.2 decreases SOCE. …”
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    A STIM2 splice variant negatively regulates store-operated calcium entry
  2. 202
    por Kraft, Robert
    Publicado 2015
    “…The isoforms ORAI2 and ORAI3 are candidates for SOCE channels in neurons and astrocytes, respectively. …”
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    STIM and ORAI proteins in the nervous system
  3. 203
    “…The essential role of store-operated Ca(2+) entry (SOCE) through Ca(2+) release-activated Ca(2+) (CRAC) channels in T cells is well established. …”
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    Orai3 and Orai1 mediate CRAC channel function and metabolic reprogramming in B cells
  4. 204
    “…Here we generate transgenic mice with muscle-specific expression of dominant-negative Orai1 (dnOrai1) and demonstrate that Orai1-dependent SOCE promotes growth and limits fatigue in adult skeletal muscle. dnOrai1 mice lack SOCE specifically in muscle but are fertile and thrive well into adulthood. …”
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    Orai1-dependent Calcium Entry Promotes Skeletal Muscle Growth and Limits Fatigue
  5. 205
    “…In neutrophils, intracellular Ca(2+) levels are regulated by several transporters and pathways, namely SERCA [sarco(endo)plasmic reticulum Ca(2+)-ATPase], SOCE (store-operated calcium entry), and ROCE (receptor-operated calcium entry). …”
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    Calcium Pathways in Human Neutrophils—The Extended Effects of Thapsigargin and ML-9
  6. 206
    “…SOCE modulators are therefore needed both as chemical probes and as therapeutic agents. …”
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    1,2,4-Oxadiazole-Bearing Pyrazoles as Metabolically Stable Modulators of Store-Operated Calcium Entry
  7. 207
    “…In this news and views, we discuss our recent publication where we described how ER-PM membrane contact sites (MCS) are modulated during store operated calcium entry (SOCE). We also examine why enforcing ER-PM MCS by tethering proteins does not not enhance, but rather inhibits SOCE.…”
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    Extending the Contacts Breaks the Flow
  8. 208
    “…SOCE is thought to function to refill Ca(2+) stores and modulate Ca(2+) signals. …”
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    Function of a STIM1 Homologue in C. elegans: Evidence that Store-operated Ca(2+) Entry Is Not Essential for Oscillatory Ca(2+) Signaling and ER Ca(2+) Homeostasis
  9. 209
    “…Acute exposure to tBHP did not block calcium influx through open SOCE channels. Activation of SOCE following thapsigargin-induced depletion of ER calcium was depressed by tBHP exposure. …”
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    Oxidative stress disruption of receptor-mediated calcium signaling mechanisms
  10. 210
    “…CONCLUSION: SOCE can serve as a candidate pharmacological target for treating NPC, as blockage of the Ca(2+) signaling via SOCE is a feasible strategy to suppress the EBV-driven malignant profiles in NPC cells.…”
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    Blockage of store-operated Ca(2+) entry antagonizes Epstein–Barr virus-promoted angiogenesis by inhibiting Ca(2+) signaling-regulated VEGF production in nasopharyngeal carcinoma
  11. 211
    “…Furthermore, using a SOCE potentiating agent, we demonstrated that in the MCL Rec-1 cell line, the SOCE is already activated in resting conditions. …”
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    Improvement of the rituximab–induced cell death by potentiation of the store-operated calcium entry in mantle cell lymphoma cell lines
  12. 212
    “…Store-operated calcium entry (SOCE) relies on the repositioning of ER tubules to form specific ER-plasma membrane junctions. …”
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    Microtubules Stabilization by Mutant Spastin Affects ER Morphology and Ca(2+) Handling
  13. 213
    “…RESULTS: HG exposure promoted increased proliferation of HCAECs in culture and that SOCE and IGFBP3 contributed to this proliferation. …”
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    Orai-IGFBP3 signaling complex regulates high-glucose exposure-induced increased proliferation, permeability, and migration of human coronary artery endothelial cells
  14. 214
    “…Store-Operated Calcium Entry (SOCE) is a universal calcium (Ca(2+)) influx mechanism expressed by several different cell types. …”
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    Pathophysiological Significance of Store-Operated Calcium Entry in Megakaryocyte Function: Opening New Paths for Understanding the Role of Calcium in Thrombopoiesis
  15. 215
    “…Store-operated Ca(2+) entry (SOCE), a Ca(2+) entryway from the extracellular space to the cytosol, has gained a significant amount of attention from muscle physiologists. …”
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    With the greatest care, stromal interaction molecule (STIM) proteins verify what skeletal muscle is doing
  16. 216
    por Webster, K, Ellender, C
    Publicado 2022
    “…The AHEAD trial included 195 patients recruited from a large trial protocol and randomised to either SOCE or SOCE+VE. Demographics including age, gender, education level and socioeconomic indices were collected. …”
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    P134 Sleep Laboratory contact in adults commencing CPAP: a post-hoc analysis of the AHEAD trial
  17. 217
    “…RESULTS: 195 patients met the eligibility criteria and were randomised to video education (n = 96) or to SOCE (n = 99). There was no significant difference in compliance at 2mths (median usage 1.7hrs IQR 0–6.2 SOCE, 4.4hrs IQR 0–6.7 video education p = 0.1), however at 12mths there was increased usage in the video education arm (median 0hrs IQR 0–5.4 standard of care, 3.8hrs IQR 0–6.87 p = 0.05). …”
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    P033 Randomised controlled trial on the efficacy of Audio-visual Health Educational materials on CPAP ADherence: The AHEAD trial
  18. 218
    “…Our findings show that PrP(C) attenuates SOCE, and Ca(2+) accumulation in the cytosol and mitochondria, by constitutively restraining Fyn activation and tyrosine phosphorylation of STIM1, a key molecular component of SOCE. …”
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    The prion protein constitutively controls neuronal store-operated Ca(2+) entry through Fyn kinase
  19. 219
    “…Signaling of tumor-cells may further involve up-regulation of pore forming Ca(2+) channel protein Orai1, which accomplishes store operated Ca(2+) entry (SOCE). This study explored the regulation of Orai1 abundance and SOCE by mAR. …”
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    Up-regulation of Orai1 expression and store operated Ca(2+) entry following activation of membrane androgen receptors in MCF-7 breast tumor cells
  20. 220
    “…Similar effects were observed with two other SOCE activators, acetylcholine and ATP, whose receptors were also found in enamel cells. …”
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    Evidence That Calcium Entry Into Calcium-Transporting Dental Enamel Cells Is Regulated by Cholecystokinin, Acetylcholine and ATP
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