Mostrando 221 - 240 Resultados de 703 Para Buscar '"Socing"', tiempo de consulta: 0.12s Limitar resultados
  1. 221
    “…STIMs and Orais are the main elements of SOCE. The potential role of SOCE in PCOS pathogenesis remains unclear. …”
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    Comprehensive Assessment of the STIMs and Orais Expression in Polycystic Ovary Syndrome
  2. 222
    “…We lastly show that constitutive SOCE in astrocytes results in thermal allodynia even in the absence of nerve injury. …”
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    Astrocyte store-operated calcium entry is required for centrally mediated neuropathic pain
  3. 223
    “…After the sarcoplasmic reticulum (SR) Ca(2+) store was depleted, SOCE was triggered upon reperfusion with 1.8 mM of Ca(2+). …”
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    Very Low-Density Lipoproteins of Metabolic Syndrome Modulates STIM1, Suppresses Store-Operated Calcium Entry, and Deranges Myofilament Proteins in Atrial Myocytes
  4. 224
    “…ORAI1 and STIM1 accomplish store-operated Ca(2+) entry (SOCE) and play a key role in platelet activation. …”
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    Effect of MgCl(2) and GdCl(3) on ORAI1 Expression and Store-Operated Ca(2+) Entry in Megakaryocytes
  5. 225
    “…Store-operated Ca(2+) entry (SOCE) is an essential pathway for Ca(2+) signaling, and regulates various vital cellular functions. …”
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    Super-Resolution Microscopy Reveals That Stromal Interaction Molecule 1 Trafficking Depends on Microtubule Dynamics
  6. 226
    “…Both constitutive and SOCE were significantly increased in flexor digitorum brevis fibers from mdx mice, while SOCE was absent in fibers from both Orai1 KO and mdx-Orai1 KO mice. …”
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    Postdevelopmental knockout of Orai1 improves muscle pathology in a mouse model of Duchenne muscular dystrophy
  7. 227
    “…It also shows that SOCE can sustain agonist-induced [Image: see text] oscillations in the absence of other [Image: see text] influx. …”
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    Activation of Store-Operated Calcium Entry in Airway Smooth Muscle Cells: Insight from a Mathematical Model
  8. 228
    “…We conclude that σ1R attenuates STIM1 coupling to Orai1 and thereby inhibits SOCE.…”
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    Sigma1 receptors inhibit store-operated Ca(2+) entry by attenuating coupling of STIM1 to Orai1
  9. 229
    “…In addition to these complex molecular rearrangements, other constituents like lipids at the plasma membrane, play critical roles orchestrating SOCE. PI(4,5)P(2) and enriched cholesterol microdomains have been shown as important signaling platforms that recruit the SOCE machinery in steps previous to Orai1 activation. …”
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    A cholesterol-binding domain in STIM1 modulates STIM1-Orai1 physical and functional interactions
  10. 230
    “…The endoplasmic reticulum (ER) Ca(2+) sensor STIM1 forms oligomers and translocates to ER–plasma membrane (PM) junctions to activate store-operated Ca(2+) entry (SOCE) after ER Ca(2+) depletion. STIM1 also interacts with EB1 and dynamically tracks microtubule (MT) plus ends. …”
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    EB1 binding restricts STIM1 translocation to ER–PM junctions and regulates store-operated Ca(2+) entry
  11. 231
    “…On the contrary, acidification mitigated SOCE and Ca(2+)(mit) overload caused by melittin. …”
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    The Mitochondrial Ca(2+) Overload via Voltage-Gated Ca(2+) Entry Contributes to an Anti-Melanoma Effect of Diallyl Trisulfide
  12. 232
    “…Although several studies have reported the effects of FM on store-operated calcium entry (SOCE) via the ORAI1 channel, which is essential during intracellular calcium signaling cascade generation for T cell activation and mast cell degranulation, the effects of its isolated constituents on SOCE remain unidentified. …”
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    Flos magnoliae constituent fargesin has an anti-allergic effect via ORAI1 channel inhibition
  13. 233
    “…Store-operated Ca(2+) entry (SOCE) is the most important Ca(2+) entry pathway in non-excitable cells. …”
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    Inhibition of Polyamine Biosynthesis Reverses Ca(2+) Channel Remodeling in Colon Cancer Cells
  14. 234
    “…Store-operated Ca(2+) entry (SOCE) is a ubiquitous mechanism regulating extracellular Ca(2+) entry to control a multitude of Ca(2+)-dependent signaling pathways and cellular processes. …”
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    Pathophysiological Effects of Overactive STIM1 on Murine Muscle Function and Structure
  15. 235
    “…RESULTS: Our data showed that the carbachol-stimulated, SOCE-mediated contraction of rat ASM was significantly increased in asthmatic rats, which could be abolished by exercise. …”
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    Exercise Reduces Airway Smooth Muscle Contraction in Asthmatic Rats via Inhibition of IL-4 Secretion and Store-Operated Ca(2+) Entry Pathway
  16. 236
    “…Store-operated Ca(2+) entry (SOCE) provides a major Ca(2+) entry route in cancer cells. …”
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    Stim and Orai mediate constitutive Ca(2+) entry and control endoplasmic reticulum Ca(2+) refilling in primary cultures of colorectal carcinoma cells
  17. 237
    “…Mediated through the combined action of STIM proteins and Orai channels, store-operated Ca(2+) entry (SOCE) functions ubiquitously among different cell types. …”
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    Calcium store refilling and STIM activation in STIM- and Orai-deficient cell lines
  18. 238
    “…In mice a naturally occurring 12-bp deletion in the myostatin gene is considered responsible for the compact phenotype (Mstn(Cmpt–dl1Abc), Cmpt) labeled by a tremendous increase in body weight along with signs of muscle weakness, easier fatigability, decreased Orai1 expression and store operated calcium entry (SOCE). Here, on the one hand, Cmpt fibers were reconstructed with venus-Orai1 but this failed to restore SOCE. …”
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    The Role of Orai1 in Regulating Sarcoplasmic Calcium Release, Mitochondrial Morphology and Function in Myostatin Deficient Skeletal Muscle
  19. 239
    “…Intracellular calcium mobilization, via Stim1 mediated SOCE channel, were studied using in the presence of PKC activator or inhibitor under a confocal microscope. …”
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    PKC-β modulates Ca(2+) mobilization through Stim1 phosphorylation
  20. 240
    “…Orai3-mediated SOCE was significantly increased in rBMECs after X-ray irradiation. …”
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    Role of Orai3-Mediated Store-Operated Calcium Entry in Radiation-Induced Brain Microvascular Endothelial Cell Injury
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