Mostrando 241 - 260 Resultados de 703 Para Buscar '"Socing"', tiempo de consulta: 0.11s Limitar resultados
  1. 241
    “…CONCLUSIONS: Elevating [Ca(2+)](o) induced SOCE by triggering the activation of CaSR and PLC. …”
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    Elevation of Extracellular Ca(2+) Induces Store-Operated Calcium Entry via Calcium-Sensing Receptors: A Pathway Contributes to the Proliferation of Osteoblasts
  2. 242
    “…CONTEXT: Ginsenoside Rb1, the main active ingredient of ginseng, exhibits ex vivo depression of store-operated calcium entry (SOCE) and related vasoconstriction in pulmonary arteries derived from pulmonary hypertension (PH) rats. …”
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    Preventive treatment with ginsenoside Rb1 ameliorates monocrotaline-induced pulmonary arterial hypertension in rats and involves store-operated calcium entry inhibition
  3. 243
    “…Purposes: Since the role of store-operated calcium entry (SOCE) in endothelium-dependent hyperpolarization (EDH)-mediated vasorelaxation of mesenteric arteries in health and colitis is not fully understood, cyclopiazonic acid (CPA), a specific inhibitor of the sarco(endo) plasmic reticulum calcium-ATPases (SERCA), was used as a SOCE activator to investigate its role in normal mice and its alteration in colitis mice. …”
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    Cyclopiazonic Acid-Induced Ca(2+) Store Depletion Initiates Endothelium-Dependent Hyperpolarization-Mediated Vasorelaxation of Mesenteric Arteries in Healthy and Colitis Mice
  4. 244
    “…YM-58483 was used as an ORAI1/SOCE inhibitor. ORAI1-knockdown cells were established by RNA interference. …”
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    Store-operated calcium entry via ORAI1 regulates doxorubicin-induced apoptosis and prevents cardiotoxicity in cardiac fibroblasts
  5. 245
    por Fall, Ibrahima Socé
    Publicado 2019
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    Ebola virus disease outbreak in Liberia: application of lessons learnt to disease surveillance and control
  6. 246
    “…SOCE-associated regulatory factor (SARAF)/TMEM66 is an endoplasmic reticulum (ER)-resident transmembrane protein that promotes SOCE inactivation and prevents Ca(2+) overfilling of the cell. …”
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    Store-operated Ca(2+) entry regulatory factor alters murine metabolic state in an age-dependent manner via hypothalamic pathways
  7. 247
    “…In vitro studies determined that MBL inhibited the EMT process through attenuating store-operated calcium entry (SOCE) signaling. It was further demonstrated that MBL promoted the ubiquitination of Orai1, an essential component of SOCE, via pyruvate dehydrogenase kinase 1 (PDK1)-serum glucocorticoid-regulated kinase 1 signaling. …”
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    Mannan-Binding Lectin Reduces Epithelial-Mesenchymal Transition in Pulmonary Fibrosis via Inactivating the Store-Operated Calcium Entry Machinery
  8. 248
    “…The downregulation of Orai1, and consequently SOCE, protects the cells from diverse apoptosis-inducing pathways, such as those induced by thapsigargin (Tg), tumor necrosis factor α, and cisplatin/oxaliplatin. …”
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    Orai1 contributes to the establishment of an apoptosis-resistant phenotype in prostate cancer cells
  9. 249
    “…We demonstrate that mouse oocytes/eggs express the two molecular components of SOCE—stromal interaction molecule 1 (Stim1) and Orai1—and expression of human (h) Stim1 increases Ca(2+) influx in a manner that recapitulates endogenous SOCE. …”
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    Ca(2+) influx and the store-operated Ca(2+) entry pathway undergo regulation during mouse oocyte maturation
  10. 250
    “…Depending on the PAMPs used, SOCE profiles and amplitudes appeared different, suggesting the involvement of different CRAC channels. …”
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    The Orai-1 and STIM-1 Complex Controls Human Dendritic Cell Maturation
  11. 251
    “…STIM proteins populate and expand cortical endoplasmic reticulum (ER) sheets to mediate store-operated Ca(2+) entry (SOCE) by trapping and gating Orai channels in ER-plasma membrane clusters. …”
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    STIM1L traps and gates Orai1 channels without remodeling the cortical ER
  12. 252
    “…However, the subcellular location for SOCE in muscle fibers has not been unequivocally identified. …”
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    Exercise-dependent formation of new junctions that promote STIM1-Orai1 assembly in skeletal muscle
  13. 253
    “…Store-operated calcium entry (SOCE) pathway is the primary source of Ca(2+) in these cells. …”
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    Inactivation of TRPM7 kinase in mice results in enlarged spleens, reduced T-cell proliferation and diminished store-operated calcium entry
  14. 254
    “…During SOCE, Ca(2+) leaves the endoplasmic reticulum, which then stimulates a second, amplifying wave of Ca(2+) influx through Orai1 into the cytoplasm. …”
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    SPLUNC1 is a negative regulator of the Orai1 Ca(2+) channel
  15. 255
    por Pan, Zui, Brotto, Marco, Ma, Jianjie
    Publicado 2014
    “…This review focuses on current advances of SOCE components, regulation and physiologic and pathophysiologic roles in muscles. …”
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    Store-operated Ca(2+) entry in muscle physiology and diseases
  16. 256
    “…In contrast to calcium influx through voltage- or neurotransmitter-gated channels, regulatory pathways that control store-operated calcium entry (SOCE) in neurons are poorly understood. Here, we report a transcriptional control of Stim1 (stromal interaction molecule 1) gene, which is a major sensor of endoplasmic reticulum (ER) calcium levels and a regulator of SOCE. …”
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    NEUROD2 Regulates Stim1 Expression and Store-Operated Calcium Entry in Cortical Neurons
  17. 257
    “…T cell activation starts with formation of second messengers that release Ca(2+) from the endoplasmic reticulum (ER) and thereby activate store-operated Ca(2+) entry (SOCE), one of the essential signals for T cell activation. …”
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    2-Methoxyestradiol and its derivatives inhibit store-operated Ca(2+) entry in T cells: Identification of a new and potent inhibitor
  18. 258
    “…Fibroblast activity is enhanced by increases in store-operated Ca(2+) entry (SOCE) and calcium release-activated calcium channel protein 1 (Orai1) levels. …”
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    Lithium Reduces Migration and Collagen Synthesis Activity in Human Cardiac Fibroblasts by Inhibiting Store-Operated Ca(2+) Entry
  19. 259
    “…While TRPC1 significantly contributes to SOCE and SOC channel activity, abrogation of Orai1 function eliminates SOCE and activation of TRPC1. …”
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    Local Ca(2+) Entry Via Orai1 Regulates Plasma Membrane Recruitment of TRPC1 and Controls Cytosolic Ca(2+) Signals Required for Specific Cell Functions
  20. 260
    “…In megakaryocytes and blood platelets SOCE and thus ORAI1 are powerful regulators of activity. …”
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    Beta-Glycerophosphate-Induced ORAI1 Expression and Store Operated Ca(2+) Entry in Megakaryocytes
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