Mostrando 381 - 400 Resultados de 703 Para Buscar '"Socing"', tiempo de consulta: 0.23s Limitar resultados
  1. 381
    “…The truncated double mutant CRACR2A(R144G/E300*) showed a pronounced defect in JNK phosphorylation as well as SOCE and strong impairment in cytokine production. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Biallelic mutations in calcium release activated channel regulator 2A (CRACR2A) cause a primary immunodeficiency disorder
  2. 382
    “…(1) Background: The basic mechanism of store-operated Ca(2+) entry (SOCE) in bovine hepatocytes (BHEC) is related to the activation of STIM1 and Orai1. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    STIM1–Orai1 Interaction Exacerbates LPS-Induced Inflammation and Endoplasmic Reticulum Stress in Bovine Hepatocytes through Store-Operated Calcium Entry
  3. 383
    “…SOCE, which has been widely characterized in non-excitable cells, plays a central role in Ca(2+)-dependent transcriptional regulation. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    STIM and Orai Mediated Regulation of Calcium Signaling in Age-Related Diseases
  4. 384
    “…Stromal Interaction Molecule1 (STIM1) is an endoplasmic reticulum membrane-localized calcium (Ca(2+)) sensor that plays a critical role in the store-operated Ca(2+) entry (SOCE) pathway. STIM1 regulates a variety of physiological processes and contributes to a plethora of pathophysiological conditions. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    MITF is a novel transcriptional regulator of the calcium sensor STIM1: Significance in physiological melanogenesis
  5. 385
    “…DPB162-AE is a valuable tool to study store-operated Ca(2+) entry (SOCE), as this compound was developed as a 2-APB analog that inhibits SOCE more potently and more selectively than 2-APB itself. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Data on cytotoxicity in HeLa and SU-DHL-4 cells exposed to DPB162-AE compound
  6. 386
    “…The store-operated calcium entry, better known as SOCE, forms the main Ca(2+) influx pathway in non-excitable cells, especially in leukocytes, where it is required for cell activation and the immune response. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Synthesis and Characterization of Store-Operated Calcium Entry Inhibitors Active in the Submicromolar Range
  7. 387
    “…Lysosomal Ca(2+) release led to reduced lysosomal Ca(2+) content which was replenished by ER Ca(2+), the largest intracellular Ca(2+) reservoir (ER → lysosome Ca(2+) refilling), which in turn activated store-operated Ca(2+) entry (SOCE). Inhibition of ER → lysosome Ca(2+) refilling by blockade of ER Ca(2+) exit channel using dantrolene or inhibition of SOCE using BTP2 inhibited lipotoxicity in vitro. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Lysosomal Ca(2+) as a mediator of palmitate-induced lipotoxicity
  8. 388
    “…A mechanism termed store-operated Ca(2+) entry (SOCE), causes depletion of endoplasmic reticulum (ER) Ca(2+) stores following T cell receptor (TCR) engagement and triggers a sustained influx of extracellular Ca(2+) through Ca(2+) release-activated Ca(2+) (CRAC) channels in the plasma membrane. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Weft, Warp, and Weave: The Intricate Tapestry of Calcium Channels Regulating T Lymphocyte Function
  9. 389
    “…The importance of store-operated Ca(2+) entry (SOCE) and the role of its key molecular regulators, STIM1 and ORAI1, in the development of cancer are emerging. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    STIM1 accelerates cell senescence in a remodeled microenvironment but enhances the epithelial-to-mesenchymal transition in prostate cancer
  10. 390
    “…We report herein that an EBV-specific microRNA (ebv-miR-BART13-3p) is significantly elevated in salivary glands (SGs) of pSS patients and we show that it targets stromal interacting molecule 1 (STIM1), a primary regulator of the store-operated Ca(2 +) entry (SOCE) pathway that is essential for SG function, leading to loss of SOCE and Ca(2 +)-dependent activation of NFAT. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Targeting the Ca(2 +) Sensor STIM1 by Exosomal Transfer of Ebv-miR-BART13-3p is Associated with Sjögren's Syndrome
  11. 391
    “…T cell receptor (TCR)–mediated induction and regulation of store-operated Ca(2+) entry (SOCE) is essential for eTreg cell differentiation and function. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Differentiation and homeostasis of effector Treg cells are regulated by inositol polyphosphates modulating Ca(2+) influx
  12. 392
    “…Depletion of phosphoinositides also inhibited SOCE based on measurement of the rise in intracellular Ca(2+) concentration after store depletion. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Texto
    Role of phosphoinositides in STIM1 dynamics and store-operated calcium entry
  13. 393
    “…These data indicated that NEM could induce believable store-operated calcium entry (SOCE) in PMA-activated neutrophils. Besides, we found that sodium nitroprusside (SNP), a donor of exogenous NO, resulted in believable SOCE in PMA-activated human neutrophils via S-nitrosylation modification. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Sulfhydryl Modification Induces Calcium Entry through IP(3)-Sensitive Store-Operated Pathway in Activation-Dependent Human Neutrophils
  14. 394
    “…The store-operated calcium (Ca(2+)) entry (SOCE) and its major mediator Stim1 have been shown to be implicated in a number of pathological processes typical for cancer. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Enhanced Stim1 expression is associated with acquired chemo-resistance of cisplatin in osteosarcoma cells
  15. 395
    “…The results confirm the notion that in pig oocytes, SOCE is involved in the maintenance of the repetitive Ca(2+) transients at fertilization.…”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Calcium oscillations in fertilized pig oocytes are associated with repetitive interactions between STIM1 and ORAI1()
  16. 396
    “…ORAI1 is a protein that forms a calcium-permeable ion channel responsible for store-operated calcium entry (SOCE) in a variety of cell types. ORAI3, a related isoform, is not a regulator of SOCE in most cell types. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    ORAI1 and ORAI3 in Breast Cancer Molecular Subtypes and the Identification of ORAI3 as a Hypoxia Sensitive Gene and a Regulator of Hypoxia Responses
  17. 397
    “…Compared with that in LT or IBA, the decreased extracellular Ca(2+) influx mediated by SOCE and elevated mitochondrial Ca(2+) uptake induced by MCU may be important mechanisms for the partial cytoplasmic Ca(2+) recovery in ET. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Priority Strategy of Intracellular Ca(2+) Homeostasis in Skeletal Muscle Fibers during the Multiple Stresses of Hibernation
  18. 398
    “…We demonstrated a higher resting Ca(2+) concentration and an increased SOCE in STIM1 mutant compared with control, together with a compensatory down-regulation of genes involved in Ca(2+) handling (RyR1, Atp2a1, Trpc1). …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Gain-of-Function STIM1 L96V Mutation Causes Myogenesis Alteration in Muscle Cells From a Patient Affected by Tubular Aggregate Myopathy
  19. 399
    “…Overexpression of Golli reduces SOCE in HeLa cells, but this inhibition is overcome by overexpressing STIM1. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Texto
    Evidence for an interaction between Golli and STIM1 in store-operated calcium entry
  20. 400
    “…RESULTS: Honokiol had a potent (EC50 ≈ 5 μmol/l) inhibitory effect on store operated calcium entry (SOCE) that was induced by activation of the M3 receptors. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Honokiol blocks store operated calcium entry in CHO cells expressing the M3 muscarinic receptor: honokiol and muscarinic signaling
Herramientas de búsqueda: RSS