Mostrando 461 - 480 Resultados de 703 Para Buscar '"Socing"', tiempo de consulta: 0.21s Limitar resultados
  1. 461
    “…This may be due to the abnormal expression and distribution of ERM and F-actin as a result of abnormal SOCE function.…”
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    Store-operated calcium entry enhances the polarization and chemotaxis of neutrophils in the peripheral venous blood of patients with bronchial asthma by upregulating ERM protein
  2. 462
    “…Re-expression of either Nir2 or Nir3 restored phagocytosis, but not SOCE, proportionally to the PM PI(4,5)P2 levels. …”
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    The lipid transfer proteins Nir2 and Nir3 sustain phosphoinositide signaling and actin dynamics during phagocytosis
  3. 463
    “…Store-operated Ca(2+) entry (SOCE) through ORAI1 channels in pancreatic acinar cells triggers acute pancreatitis, and ORAI1 inhibitors ameliorate experimental acute pancreatitis, but the role of ORAI1 in pancreatitis-associated acute lung injury has not been determined. …”
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    Neutrophil-specific ORAI1 Calcium Channel Inhibition Reduces Pancreatitis-associated Acute Lung Injury
  4. 464
    “…Here, we used antisense oligonucleotides to investigate the role in the oocyte of stromal interaction molecule (STIM) proteins that are fundamental elements of the store-operated calcium-entry (SOCE) phenomenon, as they are both sensors for Ca(2+) concentration in the intracellular reservoirs as well as activators of the membrane channels that allow Ca(2+) influx. …”
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    Differential role of STIM1 and STIM2 during transient inward (T(in)) current generation and the maturation process in the Xenopus oocyte
  5. 465
    “…Orai1, a specific nonvoltage‐gated Ca(2+) channel, has been found to be one of key molecules involved in store‐operated Ca(2+) entry (SOCE). Orai1 may associate with other proteins to form a signaling complex, which is essential for regulating a variety of physiological functions. …”
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    Orai1 forms a signal complex with BK(C) (a) channel in mesenteric artery smooth muscle cells
  6. 466
    “…Stromal interaction molecule 1 (STIM1) along with Orai1 mediates extracellular Ca(2+) entry into the cytosol through a store-operated Ca(2+) entry (SOCE) mechanism in various tissues including skeletal muscle. …”
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    STIM2 regulates both intracellular Ca(2+) distribution and Ca(2+) movement in skeletal myotubes
  7. 467
    por Soni, Hitesh, Adebiyi, Adebowale
    Publicado 2017
    “…These findings indicate that UII-induced SOCE via TRPC4 channels stimulates CaMKII/CREB-dependent GMC proliferation and ECM protein production. …”
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    Urotensin II-induced store-operated Ca(2+) entry contributes to glomerular mesangial cell proliferation and extracellular matrix protein production under high glucose conditions
  8. 468
    “…In the event of ER store depletion however, the store-operated calcium entry (SOCE) pathway is activated to restore ER calcium stores. …”
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    Ca(2+) mediates extracellular vesicle biogenesis through alternate pathways in malignancy
  9. 469
    por Dhanya, Sreeja Kumari, Hasan, Gaiti
    Publicado 2021
    “…SEPT7, a member of the septin family, functions as a negative regulator of the plasma membrane–localized store-operated Ca(2+) entry (SOCE) channel, Orai in Drosophila neurons, and in human neural progenitor cells. …”
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    Deficits Associated With Loss of STIM1 in Purkinje Neurons Including Motor Coordination Can Be Rescued by Loss of Septin 7
  10. 470
    “…Col6a1(−/−) megakaryocytes and platelets showed increased expression of stromal interaction molecule 1 (STIM1) and ORAI1, the components of store-operated calcium entry (SOCE), and activation of the mammalian target of rapamycin (mTOR) signaling pathway. …”
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    Ablation of collagen VI leads to the release of platelets with altered function
  11. 471
    “…Over the past two decades, mounting evidence has demonstrated that a mechanism known as store-operated Ca(2+) entry (SOCE) plays a crucial role in sustaining skeletal muscle contractility by facilitating Ca(2+) influx from the extracellular space during sarcoplasmic reticulum (SR) Ca(2+) depletion. …”
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    Ca(2+) entry units in a superfast fish muscle
  12. 472
    “…In summary, we identified new enhancer and protective activities for Aβ toxicity and showed that SURF4 contributes to oAβ(1–42) neurotoxicity by decreasing SOCE activity.…”
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    A Genome-Wide Functional Screen Identifies Enhancer and Protective Genes for Amyloid Beta-Peptide Toxicity
  13. 473
    “…While unspecific, 2-APB is one of the most-used agents to modulate store-operated calcium entry (SOCE) mediated by the STIM-gated Orai channels. Due to its boron core structure, 2-APB tends to readily hydrolyze in aqueous environment, a property that results in a complex physicochemical behavior. …”
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    The calcium channel modulator 2-APB hydrolyzes in physiological buffers and acts as an effective radical scavenger and inhibitor of the NADPH oxidase 2
  14. 474
    “…[Ca(2+)](cyt) measurement was performed to detect store-operated calcium entry (SOCE) in two groups, followed by determination of Orai and canonical transient receptor potential (TRPC) channels expression. …”
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    Bone Marrow-Derived Endothelial Progenitor Cells Contribute to Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats via Inhibition of Store-Operated Ca(2+) Channels
  15. 475
    “…Finally, components of the SOCE pathway were found to be poor prognostic indicators among MM patients, suggesting that this pathway is attractive for the treatment of MM.…”
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    Transient Receptor Potential C 1/4/5 Is a Determinant of MTI-101 Induced Calcium Influx and Cell Death in Multiple Myeloma
  16. 476
    “…Both the pattern of change and the peak concentrations of the Ca(2+)-bound species in the sarcoplasm (Tn, PV, ATP, and dye), the sarcolemma (NCX, SOCE), and the SR (SERCA) showed the order IIB ≥ IIX > IIA > I. …”
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    Comprehensive Simulation of Ca(2+) Transients in the Continuum of Mouse Skeletal Muscle Fiber Types
  17. 477
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    Moving to malaria elimination in Cape Verde
  18. 478
    “…The resulting cytosolic Ca(2+) transients reached peak amplitudes of 0.6–1.0 µM in the absence of external Ca(2+) and were amplified by SOCE that amounted to 28–30 nM⋅s(−1) in 1 mM external Ca(2+). …”
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    Kinetics of the thapsigargin-induced Ca(2+) mobilisation: A quantitative analysis in the HEK-293 cell line
  19. 479
    “…These differences were associated with a higher magnitude of Ca(2+) influx via store-operated Ca(2+) entry (SOCE), as a result of increased expression of SOCE components (STIM1, Orai1) in the ASM cells of small airway of BALB/c mice. …”
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    Inherent differences of small airway contraction and Ca(2+) oscillations in airway smooth muscle cells between BALB/c and C57BL/6 mouse strains
  20. 480
    “…The enhanced mitochondrial Ca(2+) signals in cells overexpressing UCP2/3 rescued SOCE upon Letm1 knock-down. In digitonin-permeabilized cells, Letm1 exclusively contributed to mitochondrial Ca(2+) uptake at low Ca(2+) conditions. …”
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    Leucine Zipper EF Hand-containing Transmembrane Protein 1 (Letm1) and Uncoupling Proteins 2 and 3 (UCP2/3) Contribute to Two Distinct Mitochondrial Ca(2+) Uptake Pathways
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