Mostrando 521 - 540 Resultados de 703 Para Buscar '"Socing"', tiempo de consulta: 0.21s Limitar resultados
  1. 521
    “…Interestingly, the ectopic overexpression of Orai3, in the two NSCLC cell lines, lead to an increase of SOCE and expression of CSCs markers. Furthermore, CD133(+) cells were unable to overexpress neither Nanog nor SOX-2 when incubated with PI3K inhibitor. …”
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    Orai3-Mediates Cisplatin-Resistance in Non-Small Cell Lung Cancer Cells by Enriching Cancer Stem Cell Population through PI3K/AKT Pathway
  2. 522
    “…Interestingly, TGF(β1) induced a higher SOCE response by increasing Orai1 mRNAs and proteins and promoted both AKT phosphorylation and cell proliferation, abolished by Orai1 silencing. …”
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    Orai1 Channel Regulates Human-Activated Pancreatic Stellate Cell Proliferation and TGF(β1) Secretion through the AKT Signaling Pathway
  3. 523
    “…This increased store-operated calcium entry (SOCE), but decreased cell proliferation and invasion. …”
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    Suppression of Calcium Entry Modulates the Expression of TRβ1 and Runx2 in Thyroid Cancer Cells, Two Transcription Factors That Regulate Invasion, Proliferation and Thyroid-Specific Protein Levels
  4. 524
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    Community engagement for successful COVID-19 pandemic response: 10 lessons from Ebola outbreak responses in Africa
  5. 525
    “…We developed a time correlated single photon counting setup having a Gaussian impulse response function (IRF) of 63ps sigma, allowing to precisely measure the scintillation rise time of various materials with 511keV excitation. In L(Y)SO:Ce we found two rise time components, the first below the resolution of our setup $\lt 10$ ps and a second component being $\sim 380$ ps. …”
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    Precise rise and decay time measurements of inorganic scintillators by means of X-ray and 511 keV excitation
  6. 526
    “…The KCa3.1 channel was shown to regulate store-operated Ca(2+) entry (SOCE) through an interaction with the Ca(2+) channel Orai1 in primary astrocytes. …”
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    Ca(2+)-dependent endoplasmic reticulum stress correlation with astrogliosis involves upregulation of KCa3.1 and inhibition of AKT/mTOR signaling
  7. 527
    “…ABSTRACT: Skeletal muscle differentiation relies on store‐operated Ca(2+) entry (SOCE) mediated by STIM proteins linking the depletion of endoplasmic/sarcoplasmic reticulum Ca(2+) stores to the activation of membrane Ca(2+)‐permeable ORAI channels. …”
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    ORAI1 channel gating and selectivity is differentially altered by natural mutations in the first or third transmembrane domain
  8. 528
    “…Orai1 plays a major role in store-operated Ca(2+) entry (SOCE) in triple-negative breast cancer (TNBC) cells. …”
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    Adenylyl Cyclase Type 8 Overexpression Impairs Phosphorylation-Dependent Orai1 Inactivation and Promotes Migration in MDA-MB-231 Breast Cancer Cells
  9. 529
    “…Both, Orai1α, and Orai1β support SOCE in MDA-MB-231-derived BCSC with similar efficiency, as well as COX activation and mammosphere formation. …”
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    Orai1α and Orai1β support calcium entry and mammosphere formation in breast cancer stem cells
  10. 530
    “…In addition, Orai1 associated with Crbn, resulting in ubiquitination and proteasomal degradation of Orai1 and alteration of SOCE-mediated calcium influx. The association of Orai1 with Crbn was attenuated during efferocytosis, leading to reduced ubiquitination of Orai1 and consequently upregulation of Orai1 and calcium influx. …”
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    Crbn modulates calcium influx by regulating Orai1 during efferocytosis
  11. 531
    “…In addition, store-operated calcium entry (SOCE) contributes to the late phase of the response. …”
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    Norepinephrine-Induced Calcium Signaling and Store-Operated Calcium Entry in Olfactory Bulb Astrocytes
  12. 532
    “…They are generated by store-operated Ca(2+) entry (SOCE) following x-ray–induced clustering of Orai1 and STIM1 and formation of a Ca(2+) release–activated Ca(2+) (CRAC) channel. …”
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    X-ray irradiation triggers immune response in human T-lymphocytes via store-operated Ca(2+) entry and NFAT activation
  13. 533
    por Lucchini, Marco
    Publicado 2020
    “…The MTD will consist of a central barrel region based on L(Y)SO:Ce crystals read out with SiPMs and two end-caps instrumented with radiation-tolerant low gain avalanche detectors. …”
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    Development of the CMS MIP timing detector
  14. 534
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    Disease surveillance for the COVID-19 era: time for bold changes
  15. 535
    “…METHODS: An extensive analysis of the Ca(2+) entry (CE) pathway in CLL B cells was performed including constitutive Ca(2+) entry, basal Ca(2+) levels, and store operated Ca(2+) entry (SOCE) activated following B cell receptor engagement or using Thapsigargin. …”
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    STIM1 at the plasma membrane as a new target in progressive chronic lymphocytic leukemia
  16. 536
    “…Disruption of the mitochondrial network in a neuroblastoma model of GDAP1-related CMT has been shown to decrease Ca(2+) entry through the store-operated calcium entry (SOCE), which caused a failure in stimulation of mitochondrial respiration. …”
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    Calcium Deregulation and Mitochondrial Bioenergetics in GDAP1-Related CMT Disease
  17. 537
    “…Store-operated calcium entry (SOCE) is an essential calcium influx mechanism in animal cells. …”
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    Heterologous calcium-dependent inactivation of Orai1 by neighboring TRPV1 channels modulates cell migration and wound healing
  18. 538
    “…The protein stromal interaction molecule 1 (STIM1) plays a pivotal role in mediating store-operated calcium entry (SOCE) into cells, which is essential for adaptive immunity. …”
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    Resonance assignment of coiled-coil 3 (CC3) domain of human STIM1
  19. 539
    “…The major drivers of cardiac muscle wasting in cancer patients are autophagy activation by the cytokine-NFkB, TGF β-SMAD(3), and angiotensin II-SOCE-STIM-Ca(2+) pathways. A lack of diagnostic markers and standard treatment protocols hinder the early diagnosis of cardiac dysfunction and the initiation of preventive measures. …”
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    Cardiac Cachexia: Unaddressed Aspect in Cancer Patients
  20. 540
    “…The important role of Ca(2+) in pathogenic store-operated calcium entry (SOCE) is well-established. Among the proteins involved in the calcium signaling pathway, Stromal interacting molecule 1 (STIM1) is a critical endoplasmic reticulum transmembrane protein. …”
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    cGAS-STING Pathway Performance in the Vulnerable Atherosclerotic Plaque
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