Mostrando 581 - 600 Resultados de 703 Para Buscar '"Socing"', tiempo de consulta: 0.23s Limitar resultados
  1. 581
    “…Microscopic analysis indicated that ET formation by LL-37 depends on storage-operated calcium entry (SOCE), mitogen-activated protein kinase (MAPK), and ERK1/2, whereas the LTF-mediated ET release is not affected by any of the here used inhibitors. …”
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    Host Defense Peptides LL-37 and Lactoferrin Trigger ET Release from Blood-Derived Circulating Monocytes
  2. 582
    “…However, barbamide enhanced the effect of the TRPV1 agonist capsaicin and enhanced store-operated calcium entry (SOCE) responses after depletion of intracellular calcium. …”
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    Barbamide Displays Affinity for Membrane-Bound Receptors and Impacts Store-Operated Calcium Entry in Mouse Sensory Neurons
  3. 583
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    Public Health Program for Decreasing Risk for Ebola Virus Disease Resurgence from Survivors of the 2013–2016 Outbreak, Guinea
  4. 584
    “…Furthermore, both the TM and SOAR domains exhibited similarities and differences between STIM1–mediated thermal sensation and store–operated calcium entry (SOCE), and the key sites of Orai1 showed similar roles in these two responses. …”
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    Molecular Mechanism Analysis of STIM1 Thermal Sensation
  5. 585
    “…Store-operated Ca(2+) entry (SOCE) is a critical Ca(2+) signaling pathway in many cell types. …”
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    The Inhibitory Helix Controls the Intramolecular Conformational Switching of the C-Terminus of STIM1
  6. 586
    “…Ca(2+) remodeling includes critical changes in store-operated Ca(2+) entry (SOCE) and Ca(2+) store content. Some changes have been investigated at the molecular level. …”
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    Transcriptomic Analysis of Calcium Remodeling in Colorectal Cancer
  7. 587
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    Genomic Epidemiology of 2015–2016 Zika Virus Outbreak in Cape Verde
  8. 588
    “…We demonstrated that exercise leads to the formation of calcium entry units (CEUs), which are intracellular junctions that reduce muscle fatigue by promoting the recovery of extracellular Ca(2+) via store-operated Ca(2+) entry (SOCE). Here, we tested the hypothesis that exercise-induced assembly of CEUs may increase the risk of HS when physical activity is performed in adverse environmental conditions (high temperature and humidity). …”
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    Store-Operated Ca(2+) Entry in Skeletal Muscle Contributes to the Increase in Body Temperature during Exertional Stress
  9. 589
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    Predicting COVID-19 Infections in Eswatini Using the Maximum Likelihood Estimation Method
  10. 590
    por Rubaiy, Hussein N.
    Publicado 2023
    “…In many cells, Ca(2+) inflow is mediated by store-operated calcium channels, and it is recognized that the store-operated calcium entry (SOCE) is mediated by the two partners: the pore-forming proteins Orai (Orai1-3) and the calcium store sensor, stromal interaction molecule (STIM1-2). …”
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    ORAI Calcium Channels: Regulation, Function, Pharmacology, and Therapeutic Targets
  11. 591
    “…Intracellular calcium signaling is essential for many cellular processes, including store-operated Ca(2+) entry (SOCE), which is initiated by stromal interaction molecule 1 (STIM1) detecting endoplasmic reticulum (ER) Ca(2+) depletion. …”
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    Molecular dynamics simulations reveal the hidden EF-hand of EF-SAM as a possible key thermal sensor for STIM1 activation by temperature
  12. 592
    “…ORAI1 is a Ca(2+) release activated Ca(2+) (CRAC) channel mediating store-operated Ca(2+) entry (SOCE) on the plasma membrane. The gene for ORAI1 is located in chromosome 12q24 where a positive linkage signal was observed in our previous affected sib-pair study of KD. …”
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    Variations in ORAI1 Gene Associated with Kawasaki Disease
  13. 593
    “…Using the calcium switch assay in the Caco-2 cell monolayer model, we found here that NaB activated AMPK mainly by increasing the calcium level, but not the ATP concentration, via promoting store-operated calcium entry (SOCE). Upon the activation of AMPK, NaB promoted the reassembly of tight junctions (TJs) based on reducing the phosphorylation of myosin II regulatory light chain (MLC2) at Ser19 and increasing phosphorylation of protein kinase C β2 (PKCβ2) at Ser660. …”
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    Sodium Butyrate Promotes Reassembly of Tight Junctions in Caco-2 Monolayers Involving Inhibition of MLCK/MLC2 Pathway and Phosphorylation of PKCβ2
  14. 594
    “…In functional inhibition assays, the blockings of NADPH oxidase, NE, MPO, SOCE, ERK 1/2, and p38 MAPK signaling pathways significantly inhibited N. caninum tachyzoite-induced NETs formation. …”
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    Canine Neutrophil Extracellular Traps Release Induced by the Apicomplexan Parasite Neospora caninum In Vitro
  15. 595
    “…Additionally, fluoxetine significantly suppresses endoplasmic reticulum (ER) calcium release and store-operated calcium entry (SOCE) activation, probably through reduction of ER calcium storage and inhibition of stromal interaction molecule 1 (STIM1) trafficking. …”
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    Selective serotonin reuptake inhibitor, fluoxetine, impairs E-cadherin-mediated cell adhesion and alters calcium homeostasis in pancreatic beta cells
  16. 596
    “…In this study we tested the hypothesis that opening mKATP channels regulates expression of the major components of store-operated Ca(2+) entry (SOCE) STIM1 and Orai1. RESULTS: Quantitative reverse transcriptase polymerase chain reaction (qRT-PCR) and western blot experiments showed that diazoxide increased expression of STIM1 and Orai1 at the mRNA and protein levels, respectively, in adult rat cardiomyocytes. …”
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    The mitochondrial K-ATP channel opener diazoxide upregulates STIM1 and Orai1 via ROS and the MAPK pathway in adult rat cardiomyocytes
  17. 597
    “…Expression levels of ORAI1, a component of store-operated Ca(2+) entry (SOCE), and PKC-βII, part of the HIPPO pathway that negatively regulates YAP/TAZ activity, were reduced by TPC2 KO and RNA interference knockdown. …”
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    Loss of Two-Pore Channel 2 (TPC2) Expression Increases the Metastatic Traits of Melanoma Cells by a Mechanism Involving the Hippo Signalling Pathway and Store-Operated Calcium Entry
  18. 598
    “…Cytosolic and intraorganellar calcium imaging of P4h-tm(−/−) cells revealed that receptor-operated calcium entry (ROCE) and store-operated calcium entry (SOCE) and calcium re-uptake by mitochondria were compromised. …”
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    Transmembrane Prolyl 4-Hydroxylase is a Novel Regulator of Calcium Signaling in Astrocytes
  19. 599
    “…For MMV compounds, we found no differences between the strains except for the compound MMV665831, which we used to investigate the store-operated calcium entry (SOCE) mechanism. The results suggest that PfSR25 may be involved in the mechanism of action of the antimalarials lumefantrine and piperaquine. …”
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    The Knockout for G Protein-Coupled Receptor-Like PfSR25 Increases the Susceptibility of Malaria Parasites to the Antimalarials Lumefantrine and Piperaquine but Not to Medicine for Malaria Venture Compounds
  20. 600
    “…Ca(2+) uptake into ameloblasts is mainly regulated by the store operated Ca(2+) entry (SOCE) before it is transported across the polarized ameloblasts to reach the insulated enamel space. …”
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    Calcium Transport in Specialized Dental Epithelia and Its Modulation by Fluoride
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