Mostrando 661 - 680 Resultados de 703 Para Buscar '"Socing"', tiempo de consulta: 0.14s Limitar resultados
  1. 661
    “…Interest has emerged in the therapeutic potential of inhibiting store operated calcium (Ca(2+)) entry (SOCE) for melanoma and other cancers because malignant cells exhibit a strong dependence on Ca(2+) flux for disease progression. …”
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    Selenoprotein K deficiency inhibits melanoma by reducing calcium flux required for tumor growth and metastasis
  2. 662
    “…TRPV4‐mediated Ca(2+) entry, in turn, promoted the concerted interplay between inositol‐1,4,5‐trisphosphate‐ and nicotinic acid adenine dinucleotide phosphate‐induced endogenous Ca(2+) release and store‐operated Ca(2+) entry (SOCE). hAFS‐CM(Hypo)‐induced intracellular Ca(2+) oscillations resulted in the nuclear translocation of the Ca(2+)‐sensitive transcription factor p65 NF‐κB. …”
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    The human amniotic fluid stem cell secretome triggers intracellular Ca(2+) oscillations, NF‐κB nuclear translocation and tube formation in human endothelial colony‐forming cells
  3. 663
    “…Moreover, the transient application of 100 μM mibefradil triggered Ca(2+) influx by store-operated Ca(2+) entry (SOCE) mediated by the ORAI channels. Our findings reveal that IP(3)R and PLC are potential new targets of mibefradil offering novel insights into the effects of this drug. …”
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    Mibefradil alters intracellular calcium concentration by activation of phospholipase C and IP(3) receptor function
  4. 664
    “…TAM is caused by gain-of-function mutations in proteins that coordinate store-operated Ca(2+) entry (SOCE): STIM1 Ca(2+) sensor proteins in the sarcoplasmic reticulum (SR) and Ca(2+)-permeable ORAI1 channels in the surface membrane. …”
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    Voluntary wheel running mitigates disease in an Orai1 gain-of-function mouse model of tubular aggregate myopathy
  5. 665
    “…Furthermore, NAADP-induced EL Ca(2+) release resulted in the Ca(2+)-dependent recruitment of ER-embedded InsP(3)Rs and SOCE activation. Transmission electron microscopy revealed clearly visible membrane contact sites between lysosome and ER membranes, which are predicted to provide the sub-cellular framework for lysosomal Ca(2+) to recruit ER-embedded InsP(3)Rs through CICR. …”
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    Nicotinic Acid Adenine Dinucleotide Phosphate Induces Intracellular Ca(2+) Signalling and Stimulates Proliferation in Human Cardiac Mesenchymal Stromal Cells
  6. 666
    “…The AITC-evoked Ca(2+) signal was triggered by the production of cytosolic, but not mitochondrial, reactive oxygen species (ROS), and was supported by store-operated Ca(2+) entry (SOCE). Conversely, the Ca(2+) response to AITC did not require Ca(2+) mobilization from the endoplasmic reticulum, lysosomes or mitochondria. …”
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    Allyl Isothiocianate Induces Ca(2+) Signals and Nitric Oxide Release by Inducing Reactive Oxygen Species Production in the Human Cerebrovascular Endothelial Cell Line hCMEC/D3
  7. 667
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    Implementing Joint External Evaluations of the International Health Regulations (2005) capacities in all countries in the WHO African region: process challenges, lessons learnt and perspectives for the future
  8. 668
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    Diabetes in an emergency context: the Malian case study
  9. 669
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    Conflict, displacement and sexual and reproductive health services in Mali: analysis of 2013 health resources availability mapping system (HeRAMS) survey
  10. 670
    “…Objective: Previous studies have demonstrated Stromal interaction molecule 1 (STIM1)-mediated store-operated Ca(2+) entry (SOCE) contributes to intracellular Ca(2+) accumulation. …”
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    Suppression of Stim1 reduced intracellular calcium concentration and attenuated hypoxia/reoxygenation induced apoptosis in H9C2 cells
  11. 671
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    Developing a multisectoral National Action Plan for Health Security (NAPHS) to implement the International Health Regulations (IHR 2005) in Tanzania
  12. 672
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    Healthcare workers’ experiences regarding scaling up of training on integrated disease surveillance and response (IDSR) in Uganda, 2016: cross sectional qualitative study
  13. 673
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    Enhancing laboratory capacity during Ebola virus disease (EVD) heightened surveillance in Liberia: lessons learned and recommendations
  14. 674
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    Lessons learned from detecting and responding to recurrent measles outbreak in Liberia post Ebola-Epidemic 2016-2017
  15. 675
    “…We also consider how the SOCE-related events could contribute to the development of PD.…”
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    Endoplasmic Reticulum-Based Calcium Dysfunctions in Synucleinopathies
  16. 676
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    Bayesian Geostatistical Modeling to Assess Malaria Seasonality and Monthly Incidence Risk in Eswatini
  17. 677
    “…Results revealed that levels of intracellular Ca(2+) and reactive oxygen species (ROS) along with the abundance of store-operated Ca(2+) entry (SOCE) moiety increased during ketosis. Further, plasma concentrations of inflammatory cytokines were elevated, the balance of Th17/Treg cells was disrupted, mitochondrial function impaired, and the abundance of mitophagy-related proteins in CD4(+) T cells altered during ketosis. …”
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    Intracellular Ca(2+) Signaling and Calcium Release-Activated Calcium Modulator ORAI1 Are Associated With CD4(+) T Lymphocytes in Dairy Cows
  18. 678
    “…In vitro assays using four synthesized AMPs showed high MIC values (e.g. So_ce_56_913 250 µg/ml and Coral_AMP411 125 µg/ml against E. coli). …”
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    In Silico and In Vitro Analyses Reveal Promising Antimicrobial Peptides from Myxobacteria
  19. 679
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    The changing risk of Plasmodium falciparum malaria infection in Africa: 2000–10: a spatial and temporal analysis of transmission intensity
  20. 680
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    The design and implementation of the re-vitalised integrated disease surveillance and response (IDSR) in Uganda, 2013–2016
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