Mostrando 101 - 120 Resultados de 703 Para Buscar '"Socing"', tiempo de consulta: 0.16s Limitar resultados
  1. 101
    “…SOCE inhibitors attenuated the assembly and disassembly of focal adhesions significantly. …”
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    Chemoresistant ovarian cancer enhances its migration abilities by increasing store-operated Ca(2+) entry-mediated turnover of focal adhesions
  2. 102
    “…However, some Ca(2+)-dependent effectors that localize away from SOCE microdomains, are activated downstream of SOCE by mechanisms that remain obscure. …”
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    Spatially restricted subcellular Ca(2+) signaling downstream of store-operated calcium entry encoded by a cortical tunneling mechanism
  3. 103
    “…Treatment by BTP2, a known SOCE blocker, decreased the initial EPI-enhanced SOCE, rescued HL-1 cells from EPI-induced apoptosis, and reduced NFAT4 nuclear translocation and hypertrophy. …”
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    Blocking Store-Operated Ca(2+) Entry to Protect HL-1 Cardiomyocytes from Epirubicin-Induced Cardiotoxicity
  4. 104
    “…In IPAH-PASMC, the small interfering RNA (siRNA)-mediated knockdown of STIM2 decreased SOCE and proliferation, while knockdown of STIM2 in control PASMC had no effect on either SOCE or proliferation. …”
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    STIM2 contributes to enhanced store-operated Ca(2+) entry in pulmonary artery smooth muscle cells from patients with idiopathic pulmonary arterial hypertension
  5. 105
    por Chakraborty, Sumita, Hasan, Gaiti
    Publicado 2017
    “…IP(3)-mediated Ca(2+) release, and the resulting depletion of the ER store, triggers entry of extracellular Ca(2+) by store-operated Ca(2+) entry (SOCE). Mutations in IP(3)R attenuate SOCE. Compromised IP(3)R function and SOCE during pupal development of Drosophila leads to flight deficits and mimics suppression of neuronal activity during pupal or adult development. …”
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    Spontaneous Ca(2+) Influx in Drosophila Pupal Neurons Is Modulated by IP(3)-Receptor Function and Influences Maturation of the Flight Circuit
  6. 106
    “…Store-operated Ca(2 +) entry (SOCE) was then measured in proliferating and differentiated N- and S-type cell populations and the expression of STIM1, Orai1 and TRPC1, three proteins reported to play a key role in SOCE, was determined. …”
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    Store-operated Ca(2 +) entry in proliferating and retinoic acid-differentiated N- and S-type neuroblastoma cells
  7. 107
    “…Store-operated Ca(2+) entry (SOCE) channels are the main pathway of Ca(2+) entry in non-excitable cells such as neural progenitor cells (NPCs). …”
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    A Role of Canonical Transient Receptor Potential 5 Channel in Neuronal Differentiation from A2B5 Neural Progenitor Cells
  8. 108
    “…Store-operated calcium entry (SOCE) regulates a wide variety of essential cellular functions. …”
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    Alternative splicing converts STIM2 from an activator to an inhibitor of store-operated calcium channels
  9. 109
    “…Store‐operated Ca(2+) entry (SOCE) machinery, including Orai channels, TRPCs, and STIM1, is key to cellular calcium homeostasis. …”
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    The interplay between mitochondria and store‐operated Ca(2+) entry: Emerging insights into cardiac diseases
  10. 110
    “…Moreover, inhibition of SOCE by antagonists and siRNA increased the expression levels of Homer1a mRNA and protein, and knockdown of Homer1a expression by specific siRNA partly reversed the protective effects induced by SOCE inhibition in PC12 cells. …”
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    Inhibition of Store-Operated Calcium Entry Attenuates MPP(+)-Induced Oxidative Stress via Preservation of Mitochondrial Function in PC12 Cells: Involvement of Homer1a
  11. 111
    “…While much is known about the regulation of SOCE by STIM1, the role of stromal interaction molecule 2 (STIM2) in SOCE remains incompletely understood. …”
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    Interplay between ER Ca(2+) Binding Proteins, STIM1 and STIM2, Is Required for Store-Operated Ca(2+) Entry
  12. 112
    “…Stromal interaction molecule 1 (STIM1) is the main protein that, along with Orai1, mediates store-operated Ca(2+) entry (SOCE) in skeletal muscle. Abnormal SOCE due to mutations in STIM1 is one of the causes of human skeletal muscle diseases. …”
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    Pathological Mechanism of a Constitutively Active Form of Stromal Interaction Molecule 1 in Skeletal Muscle
  13. 113
    por Zui, PAN, JianJie, MA
    Publicado 2014
    “…Store-operated Ca(2+) entry (SOCE) controls intracellular Ca(2+) homeostasis and regulates a wide range of cellular events including proliferation, migration and invasion. …”
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    Open Sesame: treasure in store-operated calcium entry pathway for cancer therapy
  14. 114
    “…Store-operated Ca(2+) entry (SOCE) is the major pathway of Ca(2+) entry in mammalian cells, and regulates a variety of cellular functions including proliferation, motility, apoptosis, and death. …”
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    Development of Store-Operated Calcium Entry-Targeted Compounds in Cancer
  15. 115
    “…Furthermore, suppression of SOCE could reduce the phenylephrine-induced cardiomyocyte hypertrophy, suggesting that SOCE-STIM1-Orai1 is located upstream of hypertrophy.…”
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    Gastrodin Inhibits Store-Operated Ca(2+) Entry and Alleviates Cardiac Hypertrophy
  16. 116
    “…The present study aimed to explore the specific mechanisms of SOCE in the processes of glioma migration and invasion. …”
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    Store-operated Ca(2+) entry regulates glioma cell migration and invasion via modulation of Pyk2 phosphorylation
  17. 117
    “…Store-operated Ca(2+) entry (SOCE) is one pathway that mediates Ca(2+) influx and smooth muscle contraction. …”
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    Contrasting Patterns of Agonist-induced Store-operated Ca(2+) Entry and Vasoconstriction in Mesenteric Arteries and Aorta With Aging
  18. 118
    “…Calcium/calmodulin-dependent protein kinase II (CaMKII) and neuronal store-operated calcium entry (nSOCE) have been implicated in the development of Alzheimer's disease (AD). nSOCE is involved in regulation of dendritic spine shape, particularly in stability of mushroom spines that play role in formation of strong synapses. …”
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    CaMKIIβ knockdown decreases store-operated calcium entry in hippocampal dendritic spines
  19. 119
    “…Store-operated calcium entry (SOCE) through Ca(2+) release-activated Ca(2+) (CRAC) channels regulates the function of many immune cells. …”
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    STIM1 and STIM2-mediated Ca(2+) influx regulates antitumour immunity by CD8(+) T cells
  20. 120
    “…MetS-induced alterations in cardiac calcium signaling, especially in SOCE are still unclear. Therefore, we aim to examine the possible role of SOCE and its components (STIM1 and Orai1) in the MetS-induced cardiac remodeling. …”
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    STIM1-Orai1 interaction mediated calcium influx activation contributes to cardiac contractility of insulin-resistant rats
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